Data Views Exclude Ubiquitous Chemicals

Activities: 543
All Chemicals: 405
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Chemical Low PPM High PPM StdDev *Reference
SUGARS Fruit39600.0 119800.0 -0.39 *
HESPERIDIN Pericarp-- 63500.0 0.39 Jim Duke's personal files.
Activities (31)
Analgesic
Anti-LDL
AntiDNA
AntiRNA
Antiallergenic Yakugaku Zasshi, 111: 193, 1991.
Antibradykinic Economic & Medicinal Plant Research, 5: 366.
Anticapillary-Fragility
Antiflu Economic & Medicinal Plant Research, 5: 197.
Antihistaminic
Antiinflammatory IC47=50 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antiinflammatory IC63=100 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antileukotriene
Antioxidant IC50=8 ppmPhytochemistry, 37: 1463.
Antiprostaglandin
Antistomatitic
Antitriglyceride
Antiulcer 100-150 mg/kg ipr
Antivaccinia Economic & Medicinal Plant Research, 5: 197.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Anxiolytic
CNS-Depressant 100-150 mg/kg ipr
Calcium-Antagonist IC50=1.2 uM rbt
Capillariprotective Martindale's 29th
Catabolic
Choleretic
Cyclooxygenase-Inhibitor
Hypolipidemic
Lipoxygenase-Inhibitor
Pesticide
ProHLDL
Vasopressor
NARINGENIN Pericarp35000.0 45800.0 Jim Duke's personal files.
Activities (56)
11B-HSD-Inhibitor
Aldose-Reductase-Inhibitor IC25=1 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor IC78=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor 100 uMOliveira, T. T., Nagem, T. J., Miranda, L. C. G., Paula, V. F., Teixeira, M. A. 1997. Inhibitory Action on Aldose Reductase by Soybean Flavonoids. J Braz Chem Soc, 8(3): 211-213.
Aldose-Reductase-Inhibitor 1 ug/mLAida, K., Tawata, M., Shindo, H., Onaya, T., Sasaki, H., Yamaguchi, T., Chin, M.(Chen, Z.), and Mitsuhashi, H. 1989. Isoliquiritigenin: A New Aldose Reductase Inhibitor from Glycyrrhizae Radix. Planta Medica 56(3): 254-258.
AntiHIV IC35=200 ug/ml
Antiacetylcholinesterase
Antiaflatoxin IC50=12 uM
Antiaflatoxin IC50=3.37 ppm
Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antialzheimeran
Antiamnesic
Antiamyloid-Beta
Antibacterial MIC=250-500 ug/mlPlanta Medica, 57: A43, 1991.
Anticancer
Antiescherichic
Antiestrogenic
Antifibrotic
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiherpetic Economic & Medicinal Plant Research, 5: 197.
Antiinflammatory 20 ppm
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimutagenic ID50=50-100 nMMaga, J.A. Contribution of Phenolic Compounds to Smoke Flavor. Phenolic Compounds in Food and Their Effects on Health, Ch.13.
Antioxidant 7 x quercetin
Antiperistaltic
Antiperoxidative Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiradicular 7 x quercetin
Antisindhis IC50=15 ug/ml
Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antistaphylococcic
Antitumor
Antitumor-Promoter
Antiulcer Fitoterapia No.5-1990.
Antiviral IC50=15 ug/ml
Aphidifuge
Aromatase-Inhibitor IC45=1 uM/lJournal of Medicinal Food 2: 235.1999.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Choleretic
Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima.
Decarboxylase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Embryotoxic
Estrogenic EC50=0.1-25 uM/l
Fungicide 2.5 mM
Fungistat Weidenborner, M., Hindorf, H., Jha, H.C., and Tsotsonos, P. 1989. Antifungal Activity of Flavonoids Against Storage Fungi of the Genus Aspergillus. Phytochemistry. 29(4): 1103-1105.
Hepatoprotective IC50=12 uM
Hepatoprotective IC50=3.37 ppm
Neuroprotective
P450-Inhibitor
Pesticide
Serotonin-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
TNF-alpha-Inhibitor IC50=14.41 uM
Teratogenic
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Uterotrophic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
XANTHYLETIN Root Bark-- 45000.0 Jim Duke's personal files.
Activities (1)
DME-Inhibitor IC50=57.5 uMAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
ELEMOL Root Bark-- 28200.0 Jim Duke's personal files.
Activities (2)
Antiacetylcholinesterase IC50=34 ug/ml
Antiulcer
NEOHESPERIDIN Pericarp-- 28000.0 Jim Duke's personal files.
Activities (6)
Anticancer
Antioxidant
Antioxidant 7 x quercetin
Antiradicular 7 x quercetin
Antitumor-Promoter
Cancer-Preventive
XANTHOXYLETIN Root Bark-- 24000.0 Jim Duke's personal files.
Activities (1)
Anticonvulsant
LIMONENE Fruit8300.0 9700.0 0.64 *
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
RUTIN Leaf-- 9000.0 -0.45 Jim Duke's personal files.
Activities (87)
5-HT-Inhibitor
Aldehyde-Oxidase-Inhibitor IC27-52=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelochemic
AntiCVI 270 mg/man/day
Antiaggregant ED50=33 nmol/kg iv
Antiallergic
Antiapoplectic
Antiatherogenic
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer
Anticapillary-Fragility 20-100 mg orl manMerck 7th Ed.
Anticataract
Anticlastogen
Anticonvulsant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antidementia Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antidiabetic Jin, G-Z., Yamagata, Y., and Tomita, K.-i. 1989. Structure of Rutin Pentamethanol. Chem. Pharm. Bull. 38(2): 297-300, 1990.
Antiedemic 270 mg/day orl man
Antierythemic
Antifeedant
Antiglaucomic 60 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antihematuric
Antihemorrhoidal
Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiherpetic Economic & Medicinal Plant Research, 5: 198.
Antihistaminic
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20 mg/kg
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nM
Antinephritic
Antinociceptive
Antioxidant IC28=30 ppm
Antioxidant IC50=120 uM
Antioxidant IC54=10 uM
Antiperoxidant IC50=10-20 uM
Antiplatelet
Antiproliferant 50-75 uM/l
Antiprotozoal
Antipurpuric
Antiradicular 9 x quercetin
Antispasmodic
Antisunburn
Antithrombogenic EC50=500 nM
Antithyroid IC50=68 uM
Antitrypanosomic 100 mg/kgPlanta Medica, 57: A44, 1991.
Antitumor
Antitumor-Promoter
Antiulcer
Antivaricose
Antiviral
Apoptotic 75 uM/l
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Capillariprotective Merck 11th Edition
Catabolic
Chemopreventive
Cytoprotective IC50=3 uM
Estrogenic? Economic & Medicinal Plant Research, 6: 189.
Hemostat
Hepatomagenic 20,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective 20 mg/kg rat
Hypocholesterolemic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypotensive Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Immunomodulator
Insecticide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat IC95=4,000-8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC75=2.5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Mutagenic Economic & Medicinal Plant Research, 6: 189.
Myoprotective
Myorelaxant Economic & Medicinal Plant Research, 6: 189.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PAF-Inhibitor
Pesticide
Protisticide
Radioprotective
Sunscreen
Topoisomerase-II-Inhibitor IC50=1 ug/mlBernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
Vasodilator
Vasopressor
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
RUTIN Pericarp-- 6100.0 Jim Duke's personal files.
Activities (87)
5-HT-Inhibitor
Aldehyde-Oxidase-Inhibitor IC27-52=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelochemic
AntiCVI 270 mg/man/day
Antiaggregant ED50=33 nmol/kg iv
Antiallergic
Antiapoplectic
Antiatherogenic
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer
Anticapillary-Fragility 20-100 mg orl manMerck 7th Ed.
Anticataract
Anticlastogen
Anticonvulsant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antidementia Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antidiabetic Jin, G-Z., Yamagata, Y., and Tomita, K.-i. 1989. Structure of Rutin Pentamethanol. Chem. Pharm. Bull. 38(2): 297-300, 1990.
Antiedemic 270 mg/day orl man
Antierythemic
Antifeedant
Antiglaucomic 60 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antihematuric
Antihemorrhoidal
Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiherpetic Economic & Medicinal Plant Research, 5: 198.
Antihistaminic
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20 mg/kg
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nM
Antinephritic
Antinociceptive
Antioxidant IC28=30 ppm
Antioxidant IC50=120 uM
Antioxidant IC54=10 uM
Antiperoxidant IC50=10-20 uM
Antiplatelet
Antiproliferant 50-75 uM/l
Antiprotozoal
Antipurpuric
Antiradicular 9 x quercetin
Antispasmodic
Antisunburn
Antithrombogenic EC50=500 nM
Antithyroid IC50=68 uM
Antitrypanosomic 100 mg/kgPlanta Medica, 57: A44, 1991.
Antitumor
Antitumor-Promoter
Antiulcer
Antivaricose
Antiviral
Apoptotic 75 uM/l
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Capillariprotective Merck 11th Edition
Catabolic
Chemopreventive
Cytoprotective IC50=3 uM
Estrogenic? Economic & Medicinal Plant Research, 6: 189.
Hemostat
Hepatomagenic 20,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective 20 mg/kg rat
Hypocholesterolemic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypotensive Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Immunomodulator
Insecticide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat IC95=4,000-8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC75=2.5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Mutagenic Economic & Medicinal Plant Research, 6: 189.
Myoprotective
Myorelaxant Economic & Medicinal Plant Research, 6: 189.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PAF-Inhibitor
Pesticide
Protisticide
Radioprotective
Sunscreen
Topoisomerase-II-Inhibitor IC50=1 ug/mlBernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
Vasodilator
Vasopressor
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
P-CYMENE Fruit3590.0 4070.0 -0.04 *
Activities (16)
Analgesic Martindale's 28th
Antiacetylcholinesterase IC40=1.2 mM
Antibacillary
Antibacterial
Antiflu
Antirheumatalgic Martindale's 28th
Antiviral
FLavor FEMA 12-250Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Herbicide IC50=50 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Laxative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide LD100=50 ug/ml
MALIC-ACID Fruit600.0 2000.0 -0.82 *
Activities (15)
Antiatherosclerotic
Antibacterial
Antifibromyalgic 300 mg 3x/day
Antioxidant Synergist Merck 11th Edition
Antiseborrheic
Antiseptic Martindale's 29th
Antitubercular
Antitumor Economic & Medicinal Plant Research, 6: 235.
Bacteristat
Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Hemopoietic
Laxative? Lawrence Review of Natural Products, Sep-91.
Mycobactericide
Pesticide
Sialogogue Martindale's 29th
ASPARAGINE Fruit200.0 1800.0 0.34 *
Activities (2)
Antisickling Ekeke, G.I. and Shode, F.O. 1988. Phenylalanine is the Predominant Antisickling Agent in Cajanus cajan Seed Extract. Planta Medica 56(1): 41, 1990.
Diuretic HerbalGram No. 17.
GAMMA-AMINOBUTYRIC-ACID Fruit40.0 730.0 -0.28 *
Activities (22)
Analeptic
Anticephalagic
Anticerebrotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antichoreic 1-32 g/man/dayMartindale's 29th
Anticonvulsant 4,120 mg/kg ipr musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antihypertensive 1,000-4,000 mg/man/day
Antiinsomnic
Antilethargic
Antistress
Antitinnitic
Anxiolytic
CNS-Inhibitor 0.1 mg/kg ivn catBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
CNS-Inhibitor 100 mg/kg ivn dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
CNS-Inhibitor 2,500 mg/kg scu musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiovascular 208 ivn dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Diuretic 1,500-4,000 mg/man/day
Hypotensive 1,000-4,000 mg/day
Neuroinhibitor
Neurotoxic to birdsJeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Neurotransmitter
Sedative
Tranquilizer Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
ETHYL-SUBERENOL Root Bark-- 700.0 Jim Duke's personal files.
SUBERENOL Root Bark-- 700.0 Jim Duke's personal files.
BETAINE Fruit390.0 630.0 -1.04 *
Activities (14)
Abortifacient
Antigastritic Martindale's 29th
Antihomocystinuric
Antimyoatrophic
Bruchiphobe Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Cardioprotective
Diuretic Wealth of India.
Emmenagogue Wealth of India.
Ethanolytic
Expectorant
Hepatoprotective
Lipotropic
Mucogenic
Pesticide
LINALOOL Fruit30.0 530.0 -0.44 *
Activities (53)
Acaricide C90=<15 ul/l (=<15 ppm
Allergenic
Analgesic
Anesthetic 0.01-1 ug/ml
Antiacetylcholinesterase
Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antianaphylactic
Antibacterial MIC=1,600 ug/ml
Anticariogenic MIC=1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticolic
Anticonvulsant 200 mg/kg ipr mus
Antiedemic
Antiglutamaergic
Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory
Antileukemic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antilymphomic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimange
Antimite
Antimutagenic
Antiseptic 5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antiviral
Barbituate-Synergist
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative
Culicide LC50=156-194 mg/l
Cytotoxic
Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
FLavor FEMA 2-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Acta Botanica Sinica, 32: 49.
GABA-nergic
Hypnotic
Hypothermic
Insecticide LC50=156-194 mg/l
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide LC50=156-194 mg/l
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Sedative 200 mg/kg ipr mus (1% as active as diazepam)
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Trichomonicide LD100=600 ug/ml
Tumor-Promoter
LINALOL Fruit30.0 530.0 -0.55 *
ALPHA-LINOLENIC-ACID Fruit70.0 528.0 -0.91 USDA's Ag Handbook 8 and sequelae)
Activities (15)
5-Alpha-Reductase-Inhibitor
Antiaggregant Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp.
Antihypertensive
Antiinflammatory IC50=42 uM
Antileukotriene-D4 IC50=42 uM
Antimenorrhagic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antimetastatic Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp.
Antiprostatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Hypotensive Cunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp.
Immunostimulant 0.12 ml/man/dayCunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp.
Lymphocytogenic 0.5 ug/mlCunane, S. and Thompson, L. U., eds. 1995. Flaxseed in Human Nutrition. AOCS Press, Champaign IL. 384 pp.
Propecic
Prostaglandin-Synthesis-Inhibitor 39.5 g/day/hmnFerretti, A., Flanagan, V. P. 1996. Antithromboxane Activity of Dietary Alpha-linolenic Acid: A Pilot Study. Prostaglandins Leukotrienes Essential Fatty Acids, 54(6): 451-455. ARS, USDA.
Vasodilator
CITRACRIDONE-I Root Bark-- 400.0 *
NORDENTATIN Root Bark-- 300.0 Jim Duke's personal files.
Activities (1)
Antibacterial 10-200 ppm
LIMONENE Fruit Juice1.0 278.0 *
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
PHYTOSTEROLS Fruit-- 240.0 -0.91 Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Activities (2)
Antiprostatotic
Hypocholesterolemic
SALICYLATES Fruit-- 200.0 0.24 *
Activities (7)
Antiaggregant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antipyretic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiuricosuric Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Hyperglycemic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Hypoglycemic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Uricosuric Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
FERULIC-ACID Pericarp20.0 180.0 1.0 *
Activities (61)
Allelopathic Holappa, L.D., and Blum*, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865.
Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69.
Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiarrhythmic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidysmenorrheic
Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiherpetic
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antineoplastic (Stomach)
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antioxidant 3,000 uM
Antioxidant IC51=200 ppm
Antioxidant 1/3 quercetin
Antioxidant 1/2 BHA
Antioxidant EC50=9-15 ug/ml
Antiradicular EC50=9-15 ug/ml
Antiradicular IC50=116-124 uM
Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC46=10 uMCancer Research, 48: 5941.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cholagogue Pharmazie, 46: 156, 1991.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Hepatotropic
Herbicide Angewandte Botanik 68(5/6)=1994. Page 195.
Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypolipidemic
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Phagocytotic
Preservative Merck 11th Edition
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mMXu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416.
Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92.
Uterosedative 30-100 mg/kg ivn ratOzaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
SCOPARONE Bark-- 162.5 Jim Duke's personal files.
Activities (22)
Aldose-Reductase-Inhibitor 10 ug/ml cowOkada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Analgesic
Antiatherogenic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antihepatotoxic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiimplantation
Antiinflammatory
Antiischemic
Antiproliferant Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiradicular Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiretinopathic
Antispasmodic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
CNS-Depressant 40-80 mg/kg iprNeuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Cardiac Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic
Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypocholesterolemic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Hypotensive 5-20 mg/kg ivnNeuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Immunosuppressant 10-30 uM
Myorelaxant Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Tranquilizer Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Vasodilator
6,7-DIMETHOXYCOUMARIN Bark-- 162.0 Jim Duke's personal files.
Activities (1)
Analgesic
MYRCENE Fruit130.0 140.0 -0.36 *
Activities (22)
ACE-Inhibitor 100 ug/ml
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allergenic
Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antibacterial
Anticonvulsant
Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antinitrosaminic
Antinociceptive 10-20 mg/kg ipr musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antinociceptive 20-40 mg/kg scu musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antioxidant Jim Duke's personal files.
Antispasmodic Jim Duke's personal files.
Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMA 0.5-9Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypothermic
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Myorelaxant 100-200 mg/kg
P450-2B1-Inhibitor IC50=0.14 uM
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
HESPERIDIN Fruit Juice-- 110.0 Jim Duke's personal files.
Activities (31)
Analgesic
Anti-LDL
AntiDNA
AntiRNA
Antiallergenic Yakugaku Zasshi, 111: 193, 1991.
Antibradykinic Economic & Medicinal Plant Research, 5: 366.
Anticapillary-Fragility
Antiflu Economic & Medicinal Plant Research, 5: 197.
Antihistaminic
Antiinflammatory IC47=50 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antiinflammatory IC63=100 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antileukotriene
Antioxidant IC50=8 ppmPhytochemistry, 37: 1463.
Antiprostaglandin
Antistomatitic
Antitriglyceride
Antiulcer 100-150 mg/kg ipr
Antivaccinia Economic & Medicinal Plant Research, 5: 197.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Anxiolytic
CNS-Depressant 100-150 mg/kg ipr
Calcium-Antagonist IC50=1.2 uM rbt
Capillariprotective Martindale's 29th
Catabolic
Choleretic
Cyclooxygenase-Inhibitor
Hypolipidemic
Lipoxygenase-Inhibitor
Pesticide
ProHLDL
Vasopressor
SINAPIC-ACID Pericarp45.0 100.0 1.0 *
Activities (9)
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant IC27=30 ppm
Antiperoxynitrite IC39=5 uM
Antiperoxynitrite IC60=20 uM
Antiperoxynitrite IC75=100 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
OXALIC-ACID Fruit-- 87.0 -0.3 Watt, J.M. and Breyer-Brandwijk, M.G. 1962. The Medicinal and Poisonous Plants of Southern and Eastern Africa. E. & S. Livingstone, Ltd. Edinburg & London. 1457 pp.
Activities (9)
Acaricide
Antiseptic
CNS-Paralytic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Fatal Martindale's 29th
Hemostatic Merck 11th Edition
Irritant
Pesticide
Renotoxic Merck 11th Edition
Varroacide
P-HYDROQUINONE Root Bark-- 80.0 Jim Duke's personal files.
CITRUSININE-I Root Bark-- 80.0 *
METHANOL Fruit Juice0.8 80.0 1.0 *
Activities (2)
AntiHIV EC50=<20 ug/ml
Antidote #NAME?Martindale's 29th
P-COUMARIC-ACID Pericarp5.0 75.0 1.0 *
Activities (25)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelopathic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial Pharmazie, 46: 156, 1991.
Anticlastogen
Antifertility
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antinitrosaminic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant IC24=30 ppm
Antioxidant 1/3 BHA
Antiperoxidant IC50=>100 uMPlanta Medica, 57: A54, 1991.
Antiseptic
Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitumor
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Lipoxygenase-Inhibitor IC11=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pesticide
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor
Tyrosinase-Inhibitor ID50=3,650 uM
CAFFEINE Flower-- 62.0 1.1 Jim Duke's personal files.
Activities (62)
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Adenosine-Antagonist McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Analeptic 200 scu musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Analgesic-Synergist
Antiapneic Martindale's 29th
Antiapoptotic
Antiasthmatic 5-10 mg/kg orl/manMartindale's 29th
Anticarcinogenic
Anticariogenic
Antidermatitic Martindale's 29th
Antiemetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antiflu Economic & Medicinal Plant Research, 5: 198.
Antiherpetic
Antihypotensive 250 mg/day/orl/manMartindale's 29th
Antinarcotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiobesity
Antioxidant
Antirhinitic 140 mg/day/orl/manMartindale's 29th
Antiserotonergic 40 ipr ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antiserotonergic 40 scu ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antitumor
Antitumor (Lung)
Antivaccinia
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Apoptotic
Arrhythmigenic 1,500 mg/man
CNS-Stimulant 100 orl mus
CNS-Stimulant 30 orl rat
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic 10-25 orl dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiotonic 65-500 orl catBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Catabolic Abstract (See species file)
Choleretic
Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Diuretic
Energizer 20-200 mg/man
Ergotamine-Enhancer Martindale's 29th
FLavor FEMA 125Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide
Hypertensive
Hypoglycemic
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Lypolytic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Myorelaxant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Pesticide
Phosphodiesterase-Inhibitor
Pyrogenic 60 mg/day oral hmnDaroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191.
Pyrogenic 13.3 mg/kg ipr rbtDascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
Pyrogenic 15 mg/kg ipr catDascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
Respirastimulant
Spasmogenic 1,500 mg/man
Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Tachycardic 1,500 mg/man
Teratogenic 14 orl ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Topoisomerase-I-Inhibitor 0.1 nMTohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in 'Caffeine Effect' After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132.
Topoisomerase-I-Inhibitor 75 uMShin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Topoisomerase-II-Inhibitor 99 mMShin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Vasodilator Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
CRENULATIN Root Bark-- 60.0 Jim Duke's personal files.
CAFFEIC-ACID Fruit2.0 50.0 -0.33 *
Activities (102)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allergenic
Analgesic
AntiHIV EC50=200 ug/ml
AntiLegionella
Antiadenoviral Economic & Medicinal Plant Research, 5: 207.
Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaging
Antiatherogenic
Antibacterial
Anticancer
Anticarcinogenic Economic & Medicinal Plant Research, 6: 189.
Antidepressant
Antiedemic Economic & Medicinal Plant Research, 6: 189.
Antielastase IC50=93 um/l
Antielastase IC50=86 ug/ml (475 uM)
Antiescherichic
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antigonadotropic Jim Duke's personal files.
Antihemolytic 25 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatoadenomic 200 ppm diet orl mus
Antihepatotoxic
Antiherpetic 50 ug/ml
Antiherpetic EC50=>50 ug/ml
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene
Antimelanogenic
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antiophidic
Antioxidant 50 uM
Antioxidant IC57=30 ppm
Antioxidant 1/3 quercetin
Antioxidant 30 mM
Antioxidant 1.3 x Vit. E
Antioxidant 1/2 BHA
Antiperoxidant IC50=44 uMPlanta Medica, 57: A54, 1991.
Antiperoxidant IC35=200 ug/ml
Antiperoxidant IC85=100 ug/ml
Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiprostaglandin
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 1/3 quercetin
Antiradicular 30 mM
Antiradicular IC50=32-35 uM
Antiseptic
Antispasmodic EC50=3.4-15 uMPhytotherapy Research, 4: 73.
Antistaphylococcic
Antistomatitic Economic & Medicinal Plant Research, 5: 207.
Antisunburn
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithyroid Jim Duke's personal files.
Antitumor 200 ppm diet orl mus
Antitumor (Skin)
Antitumor-Promoter IC42=10 uMCancer Research, 48: 5941.
Antiulcerogenic
Antivaccinia Economic & Medicinal Plant Research, 5: 207.
Antiviral IC50=62.5 ug/ml
Anxiolytic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
COX-2-Inhibitor IC32=100 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 2% (diet)
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Co-carcinogenic
Collagen-Sparing
Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Cytotoxic TC50=200 ug/ml
DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Fungicide MIC=0.4 mg/ml
Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol)
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.
Hepatotropic
Histamine-Inhibitor
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC27=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=62-148 uM
Lyase-Inhibitor IC50=94-164 uM
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Prooxidant
Prostaglandigenic
Sedative 500 mg
Sunscreen IC50=2.5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC91=5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC98=25 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Tumorigenic Jim Duke's personal files.
Vulnerary
Xanthine-Oxidase-Inhibitor IC50=39.21 uMMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
4-(3-METHYL-2-BUTENOXY)-ISO-NITROSO-ACETOPHENONE Pericarp-- 48.0 Jim Duke's personal files.
SYNEPHRINE Fruit15.0 43.0 *
Activities (5)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiovascular 0.25 mg/kg ivn dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Hypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Oxytocic 2.5 mg/kg ivn musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Vasoconstrictor Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
ALPHA-PINENE Fruit35.0 40.0 -0.71 *
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
CAMPESTEROL Fruit-- 40.0 -0.32 Spiller, G. A. 1996 (Spiller, G. A. Ed. 1996. CRC Handbook of Lipids in Human Nutrition. CRC Press. Boca Raton, FL. 233 pp.)
Activities (2)
Antioxidant IC37=10 uM
Hypocholesterolemic Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
CITRUSININE-II Root Bark-- 40.0 *
CITRUSIN-II Fruit-- 40.0 Jim Duke's personal files.
CAROTENOIDS Fruit12.0 35.0 -0.5 *
CAROTENOIDS Pericarp12.0 35.0 *
FERULIC-ACID Fruit10.0 30.0 -0.76 *
Activities (61)
Allelopathic Holappa, L.D., and Blum*, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865.
Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69.
Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiarrhythmic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidysmenorrheic
Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiherpetic
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antineoplastic (Stomach)
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antioxidant 3,000 uM
Antioxidant IC51=200 ppm
Antioxidant 1/3 quercetin
Antioxidant 1/2 BHA
Antioxidant EC50=9-15 ug/ml
Antiradicular EC50=9-15 ug/ml
Antiradicular IC50=116-124 uM
Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC46=10 uMCancer Research, 48: 5941.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cholagogue Pharmazie, 46: 156, 1991.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Hepatotropic
Herbicide Angewandte Botanik 68(5/6)=1994. Page 195.
Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypolipidemic
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Phagocytotic
Preservative Merck 11th Edition
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mMXu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416.
Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92.
Uterosedative 30-100 mg/kg ivn ratOzaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
DECANAL Fruit18.0 21.0 -0.6 *
DODECANAL Fruit5.0 20.0 0.99 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (2)
FLavor FEMA 1-100Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
SINAPIC-ACID Fruit7.0 19.0 0.78 *
Activities (9)
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant IC27=30 ppm
Antiperoxynitrite IC39=5 uM
Antiperoxynitrite IC60=20 uM
Antiperoxynitrite IC75=100 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
P-COUMARIC-ACID Fruit5.0 17.0 -0.69 *
Activities (25)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelopathic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial Pharmazie, 46: 156, 1991.
Anticlastogen
Antifertility
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antinitrosaminic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant IC24=30 ppm
Antioxidant 1/3 BHA
Antiperoxidant IC50=>100 uMPlanta Medica, 57: A54, 1991.
Antiseptic
Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitumor
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Lipoxygenase-Inhibitor IC11=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pesticide
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor
Tyrosinase-Inhibitor ID50=3,650 uM
VALENCENE Fruit Juice0.04 15.3 1.0 *
ALPHA-PHELLANDRENE Fruit12.0 14.0 -0.57 *
Activities (11)
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Dermal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Emetic
FLavor FEMA 10-130Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Insectiphile Pakistan Encyclopedia Planta Medica. 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Laxative
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
OCTANAL Fruit12.0 14.0 -0.61 *
CITRABASINE Root Bark-- 14.0 *
SABINENE Fruit11.0 13.0 -0.53 *
Activities (5)
Antibacterial
Antihelicobacter
Antiseptic
Antiulcer
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
CITRUSIN-III Fruit-- 13.0 Jim Duke's personal files.
BETA-PINENE Fruit11.0 13.0 -0.3 *
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
NERYL-FORMATE Fruit-- 10.0 -1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (2)
FLavor FEMA 5-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
CARVONE Fruit2.0 10.0 -0.5 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (19)
Allergenic
Antiacetylcholinesterase IC50=1.4-1.8 mM
Antiproliferative
Antiseptic 1.5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
FLavor FEMA 80-3,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Trichomonicide LD100=300 ug/ml
Vermicide
BETA-CUBEBENE Fruit-- 10.0 -0.71 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
NONANOL Fruit-- 10.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
OCTYL-ACETATE Fruit-- 10.0 -0.71 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
TETRADECANAL Fruit5.0 9.0 1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
DELTA-3-CARENE Fruit7.0 9.0 -0.6 *
Activities (8)
Allergenic?
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Antiinflammatory iprInternat. J. Oriental Med. 15(4): 194, 1990+
Dermatitigenic
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Pesticide
GERANIAL Fruit6.0 7.0 -1.0 *
Activities (13)
AntiEBV IC50=16 uM
Antiaflatoxin
Antibacterial Onawunmi, G.O., Yisak, W-A., Ogunlana,* E.O. 1984. Antibacterial Constituents In The Essential Oil Of Cymbopogon citratus (DC.) Stapf. Journal of Ethnopharmacology, 12: 279-286, 1984.
Antitumor (Colon)
Antitumor (Skin)
Antiviral IC50=16 uM
Antiyeast
Chemopreventive
Estrogenic
Fungicide
Glutathionigenic
Pesticide
Spasmolytic
BETA-SINESAL Fruit-- 6.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
LUTEOXANTHINS Fruit-- 6.0 *
CAFFEINE Leaf-- 6.0 -0.94 Jim Duke's personal files.
Activities (62)
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Adenosine-Antagonist McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Analeptic 200 scu musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Analgesic-Synergist
Antiapneic Martindale's 29th
Antiapoptotic
Antiasthmatic 5-10 mg/kg orl/manMartindale's 29th
Anticarcinogenic
Anticariogenic
Antidermatitic Martindale's 29th
Antiemetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antiflu Economic & Medicinal Plant Research, 5: 198.
Antiherpetic
Antihypotensive 250 mg/day/orl/manMartindale's 29th
Antinarcotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiobesity
Antioxidant
Antirhinitic 140 mg/day/orl/manMartindale's 29th
Antiserotonergic 40 ipr ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antiserotonergic 40 scu ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antitumor
Antitumor (Lung)
Antivaccinia
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Apoptotic
Arrhythmigenic 1,500 mg/man
CNS-Stimulant 100 orl mus
CNS-Stimulant 30 orl rat
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic 10-25 orl dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiotonic 65-500 orl catBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Catabolic Abstract (See species file)
Choleretic
Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Diuretic
Energizer 20-200 mg/man
Ergotamine-Enhancer Martindale's 29th
FLavor FEMA 125Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide
Hypertensive
Hypoglycemic
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Lypolytic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Myorelaxant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Pesticide
Phosphodiesterase-Inhibitor
Pyrogenic 60 mg/day oral hmnDaroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191.
Pyrogenic 13.3 mg/kg ipr rbtDascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
Pyrogenic 15 mg/kg ipr catDascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
Respirastimulant
Spasmogenic 1,500 mg/man
Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Tachycardic 1,500 mg/man
Teratogenic 14 orl ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Topoisomerase-I-Inhibitor 0.1 nMTohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in 'Caffeine Effect' After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132.
Topoisomerase-I-Inhibitor 75 uMShin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Topoisomerase-II-Inhibitor 99 mMShin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Vasodilator Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
ALPHA-BERGAMOTENE Fruit-- 6.0 -1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
MEVALONIC-ACID Pericarp-- 6.0 Jim Duke's personal files.
CITRUSIN-IV Fruit-- 6.0 Jim Duke's personal files.
VIT-B-6 Fruit1.0 5.0 -0.54 USDA's Ag Handbook 8 and sequelae)
NERAL Fruit4.0 5.0 -0.88 *
Activities (4)
Antibacterial Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antispasmodic
Pesticide
Termiticide LD100=5 mg/g
HEPTANAL Fruit3.0 5.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
CITRONELLAL Fruit4.0 5.0 -1.0 *
Activities (20)
Acaricide
Allergenic
Antibacterial
Antiseptic 3.8 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antistaphylococcic
Antistreptococcic
Candidicide
Embryotoxic
FLavor FEMA <1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insectifuge Merck 11th Edition
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Mutagenic?
Nematicide MIC 1 mg/mlShoyakugaku Zasshi, 44: 183.
P450-2B1-Inhibitor IC50=1.56 uM
Perfumery
Pesticide
Sedative ED=1 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Teratogenic
FERULOYL-PUTRESCINE Fruit-- 5.0 1.0 *
LINALOOL Fruit Juice0.15 4.69 1.0 *
Activities (53)
Acaricide C90=<15 ul/l (=<15 ppm
Allergenic
Analgesic
Anesthetic 0.01-1 ug/ml
Antiacetylcholinesterase
Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antianaphylactic
Antibacterial MIC=1,600 ug/ml
Anticariogenic MIC=1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticolic
Anticonvulsant 200 mg/kg ipr mus
Antiedemic
Antiglutamaergic
Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory
Antileukemic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antilymphomic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimange
Antimite
Antimutagenic
Antiseptic 5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antiviral
Barbituate-Synergist
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative
Culicide LC50=156-194 mg/l
Cytotoxic
Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
FLavor FEMA 2-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Acta Botanica Sinica, 32: 49.
GABA-nergic
Hypnotic
Hypothermic
Insecticide LC50=156-194 mg/l
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide LC50=156-194 mg/l
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Sedative 200 mg/kg ipr mus (1% as active as diazepam)
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Trichomonicide LD100=600 ug/ml
Tumor-Promoter
LINALOL Fruit Juice0.15 4.69 1.0 *
VALENCENE Fruit3.0 4.0 -1.0 *
NONANAL Fruit3.0 4.0 -0.82 *
AURAXANTHIN Fruit-- 4.0 *
PHYTOFLUENE Fruit-- 4.0 -1.0 *
QUERCETIN Fruit-- 3.4 -0.79 Jim Duke's personal files.
Activities (176)
11B-HSD-Inhibitor
5-Lipoxygenase-Inhibitor IC50 (uM)=4
ATPase-Inhibitor Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cowOkada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor IC50=0.344 uMMao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Allelochemic IC82=1 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic
AntiCrohn's 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
AntiGTF ID50=120 ug/ml
AntiHIV
AntiPMS 500 mg/2x/day/wmnPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiaflatoxin IC50=25 uM
Antiaflatoxin IC50=7.5 ppm
Antiaggregant IC50=55 uMEconomic & Medicinal Plant Research, 5: 333.
Antiaggregant 30 uM
Antiaging
Antiallergic IC50=14 uMJim Duke's personal files.
Antialzheimeran
Antianaphylactic Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic
Antiarthritic
Antiasthmatic IC50=14 uM
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uMMedline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml
Anticataract
Anticolitic 400 mg/man/3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary
Anticystitic 1,000 mg/day/4 weeks
Antidepressant
Antidermatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic
Antielastase IC50=0.8 ug/ml
Antiencephalitic Economic & Medicinal Plant Research, 5: 199.
Antiescherichic
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic
Antiflu Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric Rastitel'nye Resursy, 21: 85.
Antigonadotropic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml
Antihistaminic IC50=<10 uM
Antihydrophobic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kgFitoterapia No.5-1990.
Antileishmanic IC50=64
Antileukemic IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antileukemic 5.5-60 uM
Antileukotriene Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50
Antimalarial IC50=1-6.4 ug/mlMedicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.62 ug/ml
Antimyocarditic Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic
Antinociceptive
Antioxidant IC96=300 ppmPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant ED50=2.3 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antioxidant 4.7 x Vit. E
Antioxidant IC47=10 uM
Antipancreatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic
Antipermeability
Antiperoxidant Planta Medica, 57: A110, 1991.
Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64
Antipodriac
Antipolio Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM
Antiprostanoid
Antiprostatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uMPlanta Medica, 56(6): 695, 1990.
Antispasmodic
Antistreptococcic ID50=120 ug/ml
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic
Antitrypanosomic IC50=13
Antitumor 10 uM
Antitumor (Bladder)
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary)
Antitumor (Skin) 20 uM
Antitumor-Promoter Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer
Antiviral IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/mlAmoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM
Bacteristat 10 mg/ml
Bradycardiac Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
COMT-Inhibitor
COX-2-Inhibitor <40 uM
Calmodulin-Antagonist Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Capillariprotective Merck 11th Edition
Carcinogenic 40,000 ppm (diet) musNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic
Copper-Chelator
Cyclooxygenase-Inhibitor
Cytochrome-P450-1A2-Inhibitor
Cytotoxic ED50=70 ug/mlMatsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Cytotoxic IC82=100 ug/mlPlanta Medica, 57: A113, 1991.
Deiodinase-Inhibitor Jim Duke's personal files.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM
Estrogenic 10% genistein
Fungicide
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml
HIV-RT-Inhibitor IC50=<1 ug/mlNakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hemostat Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective
Hypoglycemic 100 mg/kg orl ratIvorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Inotropic
Insulinogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC11=1.25 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=0.1-5 uM
MAO-A-Inhibitor
MMP-9-Inhibitor 20 uM
Mast-Cell-Stabilizer
Metal-Chelator (Copper) Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM
Mutagenic
NADH-Oxidase-Inhibitor
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor IC>50=125 uM
NO-Inhibitor IC50=20 uM
NO-Synthase-Inhibitor 5-50 uM
Neuroprotective 5-25 uM
Ornithine-Decarboxylase-Inhibitor <10 uM
P450-Inducer 5 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uMFather Nature's Farmacy: The aggregate of all these three-letter citations.
PGE2-Inhibitor
PTK-Inhibitor 0.4-24 uM
Pesticide
Phospholipase-Inhibitor
Plasmodicide Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant
Prostaglandin-Synthesis-Inhibitor 40 ug/mlIbewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
Quinone-Reductase-Inducer 6 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Quinone-Reductase-Inducer 13 uM
TNF-alpha-Inhibitor IC50=3.11 uM
Teratologic
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml
Topoisomerase-I-Inhibitor IC50=42 uM
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml
Topoisomerase-II-Inhibitor IC50=23-40 uM
Tumorigenic 0.1% diet orl rat/yrJim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM
Tyrosine-Kinase-Inhibitor Economic & Medicinal Plant Research, 6: 170.
VEGF-Inhibitor
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/mlChem. & Pharm. Bull. 38: 1772.
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml
Xanthine-Oxidase-Inhibitor 3.1 uM
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
iNOS-Inhibitor IC50=20 uM
(Z)-BETA-OCIMENE Fruit2.0 3.0 -0.66 *
VALENCIAXANTHIN Fruit-- 3.0 *
ALPHA-TERPINEOL Fruit2.0 3.0 -0.41 *
Activities (23)
ACE-Inhibitor 100 ug/ml (weak activity)
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacne
Antibacterial MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antiinflammatory
Antiproliferant
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cicatrizant ED50=240 ug/g mus
FLavor FEMA 5-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 1.29 uM/fly
Interleukin-6-Inhibitor
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide IC100=5 mg/g
Transdermal
Vulnerary ED50=240 ug/g mus
LUTEIN Fruit-- 3.0 -0.58 *
Activities (15)
Antiatherosclerotic
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antimaculitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antinyctalopic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant
Antiproliferant Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiradicular
Antiretinitic Optometry
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Colon)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Prooxidant 5-40 ug/g
Quinone-Reductase-Inducer 2.5 ugMadhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Retinoprotectant Optometry
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ALPHA-SINESAL Fruit-- 3.0 -1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
PHYTOENE Fruit-- 2.0 *
GAMMA-TERPINENE Fruit1.0 2.0 -0.65 *
Activities (11)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC23=1.2 mM
Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Antioxidant Jim Duke's personal files.
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
HEXANAL Fruit1.0 2.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (5)
Antibacterial MBC=800 ug/ml
Antisalmonella MIC=400 ug/ml
Antiseptic 400-800 ug/ml
FLavor FEMA <1-5Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
BETA-CARYOPHYLLENE Fruit1.0 2.0 -0.51 *
N-METHYL-TYRAMINE Fruit-- 2.0 -1.0 *
Activities (1)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
PERILLALDEHYDE Fruit-- 2.0 -0.73 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (11)
Acaricide
Antibacterial MIC=500->1,000 ug/ml
Antimelanomic IC50=120 uM/l
Antiproliferative
Antiseptic
Candidicide MIC=500 ug/ml
Fungicide MIC=250-500 ug/ml
Mutagenic
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Sedative
Vibriocide 250 ug/mlBlaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
TERPINOLENE Fruit1.0 2.0 -0.75 *
Activities (9)
Allelochemic
Antifeedant
Antinitrosaminic
Antioxidant
Deodorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 15-60Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
GAMMA-CADINENE Fruit1.0 2.0 -0.91 *
ZETA-CAROTENE Fruit-- 2.0 -1.0 *
MUTATOXANTHIN Fruit-- 2.0 -1.0 *
ZEAXANTHIN Fruit-- 2.0 -1.0 *
Activities (5)
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatoprotective
Quinone-Reductase-Inducer Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
ALPHA-TERPINENE Fruit1.0 2.0 -0.45 *
Activities (13)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC50=1.0 mM
Antinitrosaminic
Antispasmodic
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 0.86 uM/fly
Insectifuge
P450-2B1-Inhibitor IC50=0.76 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic
ALPHA-SINENSAL Fruit1.0 2.0 -1.0 *
ALPHA-CAROTENE Fruit0.19 1.9 -0.27 *
Activities (7)
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Liver) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Lung) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Skin) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiproliferant 10 x beta-caroteneJoseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Previtamin-A
ALPHA-TERPINEOL Fruit Juice0.09 1.1 -0.65 *
Activities (23)
ACE-Inhibitor 100 ug/ml (weak activity)
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacne
Antibacterial MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antiinflammatory
Antiproliferant
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cicatrizant ED50=240 ug/g mus
FLavor FEMA 5-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 1.29 uM/fly
Interleukin-6-Inhibitor
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide IC100=5 mg/g
Transdermal
Vulnerary ED50=240 ug/g mus
ETHYL-BUTYRATE Fruit Juice0.08 1.02 *
Activities (1)
FLavor FEMA 30-1,400Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
CITRONELLOL Fruit0.7 1.0 -0.51 *
Activities (15)
Allergenic
Antibacterial
Antiseptic
Antistaphylococcic
Antistreptococcic
Candidicide
FLavor FEMA 1-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide HerbalGram No. 17.
Herbicide IC50=160 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Nematicide MLC=100 ug/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Sedative Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Trichomonicide LD100=300 ug/ml
UNDECANAL Fruit0.7 1.0 -0.58 *
Activities (2)
FLavor FEMA 1-60
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
NERYL-ACETATE Fruit0.7 1.0 -0.72 *
Activities (5)
Antiflu
Antiviral
FLavor FEMA 1-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
BETA-ELEMENE Fruit0.7 1.0 -0.57 *
Activities (5)
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antigliomic
Antiproliferant
Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Apoptotic
(E)-BETA-OCIMENE Fruit0.7 1.0 -0.8 *
NEROL Fruit0.7 1.0 -0.55 *
Activities (10)
Antibacterial HerbalGram No. 17.
Antihelicobacter
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiulcer
Estrogenic
FLavor FEMA 1-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Merck 11th Edition
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide ED100=300 ug/ml
ALPHA-THUJENE Fruit0.7 1.0 -0.6 *
NOOTKATONE Fruit-- 1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (3)
Antiulcer 20 mg/kg orl ratYamahara, J., Li, Y.H., and Tamai, Y. 1990. Anti-ulcer Effect in Rats of Bitter Cardamon Constituents. Chem. Pharm. Bull. 38(11): 3053-3054, 1990.
FLavor FEMA 3-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
ALPHA-CUBEBENE Fruit0.7 1.0 -0.62 *
ALPHA-COPAENE Fruit0.7 1.0 -0.69 *
GERANIOL Fruit0.7 1.0 -0.61 *
Activities (35)
Allergenic
Anthelmintic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antibacterial MIC=400 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antibacterial MIC=64 ug/ml
Antibacterial MBC=800 ug/ml
Anticancer (Pancreas) IC50=265 uM
Anticariogenic MIC=400 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antimelanomic IC50=150 uM/l
Antisalmonella MIC=400 ug/ml
Antiseptic 7 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiseptic MIC=64 ug/ml
Antiseptic 400-800 ug/ml
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antitubercular MIC=64 ug/ml
Antitumor Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147.
Antitumor (Pancreas) IC50=265 uM
Ascaricide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Embryotoxic
Emetic 3 x ipecacLawrence Review of Natural Products, Sep-97.
Expectorant Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
FLavor FEMA 1-10Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide IC93=2 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC100-2,000 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge 50 ppm
Insectiphile Merck 11th Edition
Mycobactericide MIC=64 ug/ml
Nematicide IC86=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Nematicide MLC=1,000 ug/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Sedative
Trichomonicide LD100=300 ug/ml
TYRAMINE Fruit-- 1.0 0.71 *
Activities (11)
Adrenergic Merck 11th Edition
Antiaggregant
Cardiovascular 0.8 ivn catBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiovascular 30 mg/kg scu musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Hypertensive Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Insectifuge Grainge, M. and Ahmed, S., Handbook of Plants with Pest-Control Properties, John Wiley & Sons, New York, NY, 1988, 470.
Neurotoxic 1 mg/kg ivn dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Pesticide
Sympathomimetic
Vasoconstrictor
Vasopressor
OCTOPAMINE Fruit-- 1.0 -1.0 *
HEXANAL Fruit Juice0.02 0.65 *
Activities (5)
Antibacterial MBC=800 ug/ml
Antisalmonella MIC=400 ug/ml
Antiseptic 400-800 ug/ml
FLavor FEMA <1-5Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
ETHYL-ACETATE Fruit Juice0.01 0.58 *
Activities (6)
Antispasmodic
CNS-Depressant Martindale's 29th
Carminative
FLavor FEMA 20-1,500Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Respirotoxic >400 ppmAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Stimulant
MYRICETIN Fruit-- 0.5 -0.75 Jim Duke's personal files.
Activities (34)
Allelochemic IC82=1 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
AntiHIV
Antiallergenic
Antibacterial MIC=20-500 ug/ml
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antigastric
Antigingivitic MIC=20 ug/ml
Antigonadotrophic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihistaminic
Antiinflammatory Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)
Antimutagenic ID50=2-5 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant IC99=200 ppmPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant 1.4 uM
Antioxidant IC50=3.9 ug/ml
Antiperiodontic MIC=20 ug/ml
Antiplaque MIC=20 ug/ml
Antiseptic MIC=20 ug/ml
Antiviral
Apoptotic 60 uM
COMP-Inhibitor Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide MIC=150 ug/mlPlanta Medica, 57: A43, 1991.
Diuretic Oriental Materia Medica (three volumes by Dr. Hsu and collaborators)
Hypoglycemic Economic & Medicinal Plant Research, 6: 170.
Larvistat IC50=2.6-3.5 mM/kg dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Mutagenic Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Oxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Quinone-Reductase-Inducer 36 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Topoisomerase-I-Inhibitor IC50=11.9 ug/ml
Topoisomerase-II-Inhibitor IC50=11.9 ug/ml
Tyrosine-Kinase-Inhibitor Economic & Medicinal Plant Research, 6: 170.
Vasodilator
MEVALONIC-ACID Fruit-- 0.5 -0.61 Jim Duke's personal files.
GAMMA-TERPINENE Fruit Juice0.04 0.46 -1.0 *
Activities (11)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC23=1.2 mM
Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Antioxidant Jim Duke's personal files.
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
CAFFEINE Bud-- 0.3 Jim Duke's personal files.
Activities (62)
(+)-Inotropic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Adenosine-Antagonist McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Analeptic 200 scu musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Analgesic-Synergist
Antiapneic Martindale's 29th
Antiapoptotic
Antiasthmatic 5-10 mg/kg orl/manMartindale's 29th
Anticarcinogenic
Anticariogenic
Antidermatitic Martindale's 29th
Antiemetic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antiflu Economic & Medicinal Plant Research, 5: 198.
Antiherpetic
Antihypotensive 250 mg/day/orl/manMartindale's 29th
Antinarcotic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiobesity
Antioxidant
Antirhinitic 140 mg/day/orl/manMartindale's 29th
Antiserotonergic 40 ipr ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antiserotonergic 40 scu ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antitumor
Antitumor (Lung)
Antivaccinia
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Apoptotic
Arrhythmigenic 1,500 mg/man
CNS-Stimulant 100 orl mus
CNS-Stimulant 30 orl rat
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic 10-25 orl dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Cardiotonic 65-500 orl catBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Catabolic Abstract (See species file)
Choleretic
Coronary-Dilator McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Diuretic
Energizer 20-200 mg/man
Ergotamine-Enhancer Martindale's 29th
FLavor FEMA 125Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide
Hypertensive
Hypoglycemic
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Lypolytic Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Myorelaxant McKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Pesticide
Phosphodiesterase-Inhibitor
Pyrogenic 60 mg/day oral hmnDaroca, P., Rodriguez, J., Reano, M., Canto, G., Miranda, P. 1996. Fever From Caffeine. Allergy, 51(3): 189-191.
Pyrogenic 13.3 mg/kg ipr rbtDascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
Pyrogenic 15 mg/kg ipr catDascombe, M. J. 1977. Effects of Methylxanthine Drugs on Pyrogen-Induced Hyperthermia. Eur J Pharmacol, 45: 389-392.
Respirastimulant
Spasmogenic 1,500 mg/man
Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Tachycardic 1,500 mg/man
Teratogenic 14 orl ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Topoisomerase-I-Inhibitor 0.1 nMTohda, H., Zhao, J. H., Oikawa, A. 1992. A Possible Involvement of DNA Topoisomerase I in 'Caffeine Effect' After Ultraviolet Irradiation. Tohoku J Exp Med, 168: 129-132.
Topoisomerase-I-Inhibitor 75 uMShin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Topoisomerase-II-Inhibitor 99 mMShin, C. G., Strayer, J. M., Wani, M., Snapka, R. M. 1990. Rapid Evaluation of Topoisomerase Inhibitors: Caffeine Inhibition of Topoisomerases in vivo. Teratogen Carcinogen Mutagen, 10: 41-52.
Vasodilator Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cGMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
OCTANAL Fruit Juice-- 0.28 -1.0 *
HEXANOL Fruit Juice0.02 0.22 *
Activities (3)
Antiseptic
FLavor FEMA 0.2-25Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
ALPHA-PINENE Fruit Juice-- 0.22 -1.0 *
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
SABINENE Fruit Juice-- 0.15 *
Activities (5)
Antibacterial
Antihelicobacter
Antiseptic
Antiulcer
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
DECANAL Fruit Juice-- 0.15 -1.0 *
TRANS-2-HEXENOL Fruit Juice-- 0.1 *
Activities (1)
FLavor FEMA <1-1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
OCTANOL Fruit-- 0.1 -0.71 *
CAMPHENE Fruit-- 0.1 -0.35 *
Activities (9)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Jim Duke's personal files.
Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
FLavor FEMA 15-175Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Spasmogenic Fitoterapia No.59-1984.
THYMOL Fruit-- 0.1 -0.71 *
Activities (71)
Acaricide
Allergenic
Analgesic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Ancylostomicide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Anesthetic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Ankylostomacide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Anthelmintic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiacne Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Antiaggregant IC50=0.75Tramil, 42: 511.
Antialzheimeran? L. Gracza (1985) as cited by Buchbauer re antiacetylcholinesterase.
Antiarthritic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antiatherosclerotic IC50=4 uM
Antibacterial MIC=50-400 ug/ml
Antibronchitic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Anticariogenic MIC=200-400 ug/ml
Anticholinesterase L. Gracza (1985) as cited by Buchbauer re antiacetylcholinesterase.
Antihalitosic American Health, 12(4): 17, 1993.
Antiherpetic Martindale's 28th
Antiinflammatory (=indomethacin)
Antilepric Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antimelanomic IC50=120 uM/l
Antineuritic
Antioxidant 100 ppmMartindale's 28th
Antioxidant (LDL) IC50=4 uM
Antiperiodontic MIC=50-200 ug/ml
Antiplaque MIC=39-625 ug/mlOsawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21
Antiradicular EC=60Jimenez, J., Navarro, M.C., Montilla, M.P., Martin, A. and Martinez, A. 1993. Thymus zygis Oil: Its Effects on CCl4-Induced Hepatotoxicity and Free Radical Scavenger Activity. JEO5: 153-8.
Antirheumatic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antisalmonella
Antiseptic 20 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antispasmodic
Antistaphylococcic
Antistreptococcic MIC=200-400 ug/ml
Antitrichinosic 5%Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antitussive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Ataxigenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Candidicide 100 ug/ml (>Nystatin)
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Counterirritant Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Culicide LC50=36-49 mg/l
Cyclooxygenase-Inhibitor (=indomethacin)
Dentifrice Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Deodorant Martindale's 28th
Dermatitigenic
Enterorelaxant J. Aromatherapy 4: 22.
Enterotoxic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Expectorant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
FLavor FEMA 2-100Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Merck 11th Edition
Gastroirritant Martindale's 29th
Gram(+)icide MIC=200-400 ug/ml
Gram(-)icide MIC=50-200 ug/ml
Insecticide LC50=36-49 mg/l
Insecticide 0.22 uM/fly
Insectifuge
Irritant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Larvicide 10 ppmBerenbaum, M. R., The natives knew, Chemtech, (May), 1990, 275-279.
Larvicide 58 ppm
Larvicide LC50=36-49 mg/l
Molluscicide
Myorelaxant J. Aromatherapy 4: 22.
Nematicide MLC=0.1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Sprout-Inhibitor Duke, J.A.. Personal Communication.
Tracheorelaxant
Trichomonicide LD100=25 ug/ml
Urinary-Antiseptic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Varroacide
Vermicide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
TERPINEN-4-OL Fruit-- 0.1 -0.36 *
Activities (23)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacetylcholinesterase IC21-24=1.2 mM
Antiacne
Antiallergic
Antiasthmatic Chin. J. Tuber. Respir. Dis., 4:203, 1982.
Antibacterial
Antioxidant
Antiseptic Flav. & Frag. J. 9: 129.
Antispasmodic
Antitussive Chin. J. Tuber. Respir. Dis.
Antiulcer
Bacteriostatic Chin. J. Tuber. Respir. Dis.
Diuretic 0.1 ml/rat
Fungicide
Herbicide IC50=200 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=22 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge
Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Renoirritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Spermicide ED100=0.015
Vulnerary Lawrence Review of Natural Products, Jan-91.
METHYL-N-METHYL-ANTHRANILATE Fruit-- 0.1 *
ALPHA-HUMULENE Fruit-- 0.1 -0.6 *
Activities (2)
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
GERANYL-ACETATE Fruit-- 0.1 -0.94 *
Activities (5)
Allergenic
FLavor FEMA 1-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sedative Jim Duke's personal files.
TRANS-SABINENE-HYDRATE Fruit-- 0.1 -0.52 *
METHYL-BUTYRATE Fruit Juice0.01 0.1 *
Activities (2)
FLavor FEMA 20-100Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
CIS-SABINENE-HYDRATE Fruit-- 0.1 -0.71 *
FARNESENE Fruit-- 0.1 -1.0 *
Activities (2)
Pesticide
Pheromone Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CITRONELLYL-ACETATE Fruit-- 0.1 -1.0 *
Activities (2)
FLavor FEMA <1-700Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
2-METHYL-1-PROPANOL Fruit Juice-- 0.07 *
SILVER Fruit0.027 0.055 -0.59 *
Activities (3)
Antibacterial Martindale's 28th
Astringent
Pesticide
PHYLLOQUINONE Fruit-- 0.001 -0.23 *
Activities (5)
Antihemorrhagic 1 mg ims manMartindale's 28th
Fungicide
Hypotensive
Pesticide
Toxic Martindale's 28th
VALENCIACHROME Fruit-- -- *
HORDENINE Fruit-- -- *
Activities (8)
Antiasthmatic
Antidiarrheic 35 mg/kg scu dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Antifeedant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Bronchorelaxant
Cardiotonic 2 mg/cat ivnBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Hepatoprotective
Pesticide
Vasoconstrictor
SCUTELLAREIN Fruit-- -- *
Activities (7)
Aldose-Reductase-Inhibitor IC56=10uM; IC10=1uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Antihemolytic
Antileukemic IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antioxidant ED=uM
Antiviral IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Phospholipase-A2-Inhibitor Somasundaram, S., Sadique, J. 1985. Anti-hemolytic Effect of Flavonoidal Glycosides of Clerodendron inerme: An in vitro Study. Fitoterapia 57(2): 103, 1986.
CITFLAVANONE Root-- -- Jim Duke's personal files.
3-(4-METHYL-HEXYL)-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
LIMONOATE-A-RING-LACTONE Fruit-- -- Jim Duke's personal files.
NOBELITIN Fruit-- -- *
JASMONIC-ACID Fruit-- -- Jim Duke's personal files.
LUTEIN Pericarp-- -- Jim Duke's personal files.
Activities (15)
Antiatherosclerotic
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antimaculitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antinyctalopic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant
Antiproliferant Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiradicular
Antiretinitic Optometry
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Colon)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Prooxidant 5-40 ug/g
Quinone-Reductase-Inducer 2.5 ugMadhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Retinoprotectant Optometry
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NOBILETIN Fruit-- -- *
Activities (8)
Antiallergic
Antihistaminic ED=50 mg/kg
Antiproliferative IC70=8ug/ml
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cholinergic
Fungicide
Fungistat Weidenborner, M., Hindorf, H., Jha, H.C., and Tsotsonos, P. 1989. Antifungal Activity of Flavonoids Against Storage Fungi of the Genus Aspergillus. Phytochemistry. 29(4): 1103-1105.
Pesticide
ETROGOL Root-- -- Jim Duke's personal files.
BETA-ZEACAROTENE Pericarp-- -- Jim Duke's personal files.
5,6-DIHYDRO-BETA-BETA-CAROTEN-3,3',5,6-TETROL Fruit Juice-- -- *
CRYPTOFLAVIN Pericarp-- -- *
AURAPTENE Fruit-- -- *
Activities (8)
Antiperoxidant
Antisuperoxidogenic
Antitumor (Colon crypts) (rat)
Antitumor (Mouth) (rat)
Antitumor (Skin) (mouse)
Chemopreventive-Inhibitor
Quinone-Reductase-Inducer 100 ppm
Quinone-Reductase-Inducer 400 mg/kg igs ratTanaka,T. et al.1998.Citrus Auraptene Exerts Dose-Dependent Chemopreventive Activity in Rat Large Bowel Tumorigenesis:The Inhibition Correlates with Suppression of Cell Proliferation & Lipid Peroxidation & with Induction of Phase II-. Cancer Res.58:2550.
2'-TRANS-O-FERULOYL-GALACTARIC-ACID Pericarp-- -- Jim Duke's personal files.
GIBBERELLIC-ACID Fruit-- -- Jim Duke's personal files.
ISOSINENSETIN Pericarp-- -- Jim Duke's personal files.
NARINGENIN-4-BETA-D-GLUCOSIDE Plant-- -- *
3-METHYL-BUTAN-1-OL Fruit Juice-- -- Jim Duke's personal files.
NOOTKATONE Pericarp Essent. Oil-- -- Jim Duke's personal files.
Activities (3)
Antiulcer 20 mg/kg orl ratYamahara, J., Li, Y.H., and Tamai, Y. 1990. Anti-ulcer Effect in Rats of Bitter Cardamon Constituents. Chem. Pharm. Bull. 38(11): 3053-3054, 1990.
FLavor FEMA 3-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
NEOCHROME-B Pericarp-- -- Jim Duke's personal files.
ICHANGIN-17-O-BETA-D-GLUCOSIDE Seed-- -- Jim Duke's personal files.
VIOLAXANTHIN Pericarp-- -- Jim Duke's personal files.
Activities (2)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DELTA-CADINENE Pericarp-- -- *
Activities (9)
Aldose-Reductase-Inhibitor
Antiacne
Antibacterial MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antistreptococcic
Cytochrome-P450-Inducer
P450-Inducer
Pesticide
Testosterone-Inducer
SUBAPHYLLIN Leaf-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (3)
Antiviral Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
BETA-CRYPTOXANTHIN Pericarp-- -- Jim Duke's personal files.
Activities (2)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Vitamin-A-Activity
4-PHENYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
MANNOSE Fruit-- -- *
Activities (3)
AntiUTI
Antiadhesive
Anticystitic 0.25-1 tsp 3-4 x/day orl man
ABSCISIC-ACID Tissue Culture-- -- Jim Duke's personal files.
NARINGIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Fruit Juice-- -- Jim Duke's personal files.
CASTASTERONE Pollen Or Spore-- -- Jim Duke's personal files.
2-PHENYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
CARYOPHYLLENE Pericarp Essent. Oil-- -- Jim Duke's personal files.
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
LIMONIN Fruit-- -- *
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
NEUROSPORIN Pericarp-- -- Jim Duke's personal files.
LINOMIN Leaf-- -- Jim Duke's personal files.
BETA-SINENSAL Pericarp-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
BETA-SINESAL Pericarp-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
HEPTAMETHOXY-FLAVONE Fruit Juice-- -- Jim Duke's personal files.
SINENSETIN Pericarp-- -- Jim Duke's personal files.
Activities (2)
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
PHLORIN Plant-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
BRASSINOLIDE Pollen Or Spore-- -- Jim Duke's personal files.
Activities (3)
Juvabional Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Phytohormonal 1 ppmRussell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134.
NOMILINIC-ACID-17-O-BETA-D-GLUCOSIDE Seed-- -- Jim Duke's personal files.
SUBAPHYLLIN Fruit-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (3)
Antiviral Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
CRYPTOFLAVIN-B Pericarp-- -- Jim Duke's personal files.
3-PROPYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
MALONIC-ACID Plant-- -- *
Activities (1)
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
3-HYDROXY-ETHYL-HEXANOATE Fruit Juice-- -- Jim Duke's personal files.
NARINGIN-GLUCOSIDE Flower-- -- Jim Duke's personal files.
CAPRYLIC-ACID Fruit-- -- *
Activities (5)
Antiseptic
Candidicide 300 mg/man/12 x/day
Fungicide
Irritant
Pesticide
5,6-DIHYDRO-BETA-BETA-CAROTENE-3,3',5,6-TETROL Fruit Juice-- -- Jim Duke's personal files.
2-PENTYLPYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
LIMONEXIC-ACID Fruit-- -- *
CARYOPHYLLENE Pericarp-- -- *
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
LIMONIN-17-O-BETA-D-GLUCOSIDE Seed-- -- Jim Duke's personal files.
ALPHA-SINENSAL Pericarp-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
3-METHYL-BUTAN-1-OL Fruit-- -- *
CONIFERIN Pericarp-- -- Jim Duke's personal files.
Activities (2)
Herbicide IC90-95=1,000 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Pesticide
ARABAN Fruit-- -- *
TETRA-O-METHYL-SCUTELLAREIN Fruit-- -- *
3,3',4,5,6,7,8-HEPTAMETHOXY-FLAVONE Fruit Juice-- -- Jim Duke's personal files.
SINENSETIN Fruit Juice-- -- Jim Duke's personal files.
Activities (2)
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
4,7-DIMETHYL-BICYCLO(3.2.1)-OCT-TRANS-3-EN-6-ONE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOMILINIC-ACID-GLUCOSIDE Fruit Juice-- -- Jim Duke's personal files.
ALPHA-HYDROXY-CAROTENE Pericarp-- -- Jim Duke's personal files.
STACHYDRINE Fruit-- -- *
Activities (6)
Cardiotonic
Emmenagogue Lawrence Review of Natural Products, Mar-91.
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Lactagogue Lawrence Review of Natural Products, Mar-91.
Oxytocic?
Systolic-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CRYPTOFLAVIN-A Pericarp-- -- Jim Duke's personal files.
3-PHENYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
OCTAN-1-AL Fruit-- -- Jim Duke's personal files.
SINENSETIN Plant-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (2)
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
NARINGIN Flower-- -- Jim Duke's personal files.
Activities (12)
Aldose-Reductase-Inhibitor Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antidermatitic
Antiinflammatory
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antineuropathic Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antioxidant
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Myorelaxant Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
CAPRIC-ACID Fruit-- -- *
Activities (3)
Fungicide
Irritant
Pesticide
5,8-EPOXY-5,5',8'-TETRAHYDRO-BETA-BETA-CAROTENE-3,3',5',6'-TETROL Fruit Juice-- -- Jim Duke's personal files.
2-METHYL-5-PHENYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
ISOSAKURANETIN Fruit-- -- *
LIMONIN-GLUCOSIDE Fruit Juice-- -- Jim Duke's personal files.
TRANS-2-HEXENAL Pericarp-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (4)
FLavor FEMA 0.7-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Paramecicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Pesticide
Prosticide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
3-METHYL-BUT-1-ENE Essential Oil-- -- Jim Duke's personal files.
CITRUSINS Plant-- -- J.S. Glasby Dict.Pls Containing 2ndary Metabolite. 1991.
APOVIOLAXANTH-10'-AL Pericarp-- -- *
FERULIC-ACID Fruit Juice-- -- Jim Duke's personal files.
Activities (61)
Allelopathic Holappa, L.D., and Blum*, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865.
Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69.
Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiarrhythmic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidysmenorrheic
Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiherpetic
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antineoplastic (Stomach)
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antioxidant 3,000 uM
Antioxidant IC51=200 ppm
Antioxidant 1/3 quercetin
Antioxidant 1/2 BHA
Antioxidant EC50=9-15 ug/ml
Antiradicular EC50=9-15 ug/ml
Antiradicular IC50=116-124 uM
Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC46=10 uMCancer Research, 48: 5941.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cholagogue Pharmazie, 46: 156, 1991.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Hepatotropic
Herbicide Angewandte Botanik 68(5/6)=1994. Page 195.
Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypolipidemic
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Phagocytotic
Preservative Merck 11th Edition
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mMXu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416.
Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92.
Uterosedative 30-100 mg/kg ivn ratOzaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
SINAPIC-ACID Fruit Juice-- -- Jim Duke's personal files.
Activities (9)
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant IC27=30 ppm
Antiperoxynitrite IC39=5 uM
Antiperoxynitrite IC60=20 uM
Antiperoxynitrite IC75=100 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
PECTINESTERASE Fruit-- -- Jim Duke's personal files.
4,7-DIMETHYL-BICYCLO(3.2.1)-OCT-CIS-3-EN-6-ONE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOMILIN-17-O-BETA-D-GLUCOSIDE Seed-- -- Jim Duke's personal files.
HESPERIDIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Fruit-- -- *
SINESETIN Plant-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P-COUMARIC-ACID Fruit Juice-- -- Jim Duke's personal files.
Activities (25)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelopathic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial Pharmazie, 46: 156, 1991.
Anticlastogen
Antifertility
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antinitrosaminic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant IC24=30 ppm
Antioxidant 1/3 BHA
Antiperoxidant IC50=>100 uMPlanta Medica, 57: A54, 1991.
Antiseptic
Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitumor
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Lipoxygenase-Inhibitor IC11=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pesticide
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor
Tyrosinase-Inhibitor ID50=3,650 uM
3-PENTYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
OBACUNONE Seed-- -- Jim Duke's personal files.
Activities (3)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
NARINGIN Pericarp-- -- Jim Duke's personal files.
Activities (12)
Aldose-Reductase-Inhibitor Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antidermatitic
Antiinflammatory
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antineuropathic Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antioxidant
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Myorelaxant Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
GALACTURONIC-ACID Fruit-- -- *
ALPHA-COPAENE Pericarp-- -- *
ISORHOIFOLIN Pericarp-- -- *
NEROLIDOL Flower-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (11)
Aldose-Reductase-Inhibitor
Allergenic
Antiacne
Antibacterial MIC=25-200 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC=25-200 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antifeedant 1 mM (diet)Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antistreptococcic
FLavor FEMA 1-10Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
LIMONIN Seed-- -- Jim Duke's personal files.
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
ETA-CAROTENE Pericarp-- -- *
DELPHINIDIN-3-GLUCOSIDE Fruit-- -- *
Activities (1)
Antioxidant
3-HYDROXY-ETHYL-HEXANOATE Fruit-- -- Jim Duke's personal files.
VIOLAXANTHIN Fruit-- -- *
Activities (2)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
HESPERIDIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Fruit Juice-- -- Jim Duke's personal files.
VIOLAXANTHIN Tissue Culture-- -- Jim Duke's personal files.
Activities (2)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NEOCHROME-A Pericarp-- -- Jim Duke's personal files.
ZETA-CAROTENE-B Pericarp-- -- Jim Duke's personal files.
2-METHYL-5-(1-METHYL-ETHENYL)-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
APIGENIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Leaf-- -- *
NEOERIOCITRIN Flower-- -- Jim Duke's personal files.
TETRA-O-METHYL-SCUTELLAREIN Fruit Juice-- -- Jim Duke's personal files.
2-(METHYL-AMINO)-BENZYL-ALCOHOL Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOMILIN Fruit Juice-- -- Jim Duke's personal files.
Activities (2)
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
SINENSIAXANTHIN Fruit-- -- *
COUMARIC-ACID Fruit Juice-- -- Jim Duke's personal files.
3-OCTYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
LUTEOLIN-7-O-BETA-D-RUTINOSIDE Leaf-- -- Jim Duke's personal files.
NARINGIN Fruit Juice-- -- Jim Duke's personal files.
Activities (12)
Aldose-Reductase-Inhibitor Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antidermatitic
Antiinflammatory
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antineuropathic Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antioxidant
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Myorelaxant Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
ALPHA-YLANGENE Pericarp-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
GALACTAN Fruit-- -- *
LIMONIN Fruit Juice-- -- Jim Duke's personal files.
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
BERGAPTEN Pericarp-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Activities (26)
Antiaggregant
Antiapertif
Anticonvulsant
Antihistaminic 25 mg/kg ipr mus
Antiinflammatory
Antijet-lag Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Antileukodermic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimitotic 5-25 ug/mlGawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Antiplatelet
Antipsoriac
Antispasmodic
Antitumor
CNS-Depressant Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Calcium-Antagonist
Cancer-Preventive 5-25 ug/mlGawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Carcinogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DME-Inhibitor IC50=96 uMAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
Hypotensive
Insecticide
Lipolytic
Molluscicide
Mutagenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Phototoxic
Piscicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
EPOXY-VALENCENE Fruit-- -- *
BETA-CRYTOXANTHIN Fruit-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
3,3',4,5,6,7,8-HEPTAMETHOXY-FLAVONE Fruit-- -- Jim Duke's personal files.
VALENCIC-ACID Root-- -- Jim Duke's personal files.
NEOHESPERIDIN Fruit Juice-- -- Jim Duke's personal files.
Activities (6)
Anticancer
Antioxidant
Antioxidant 7 x quercetin
Antiradicular 7 x quercetin
Antitumor-Promoter
Cancer-Preventive
EPOXY-VALENCENE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NEO-BETA-CAROTENE Pericarp-- -- Jim Duke's personal files.
ALPHA-CAROTENE Pericarp-- -- Jim Duke's personal files.
Activities (7)
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Liver) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Lung) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Skin) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiproliferant 10 x beta-caroteneJoseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Previtamin-A
PHYTOFLUENE-B Pericarp-- -- Jim Duke's personal files.
ISOPRENE Essential Oil-- -- Jim Duke's personal files.
ANTHERAXANTHIN Fruit-- -- *
Activities (1)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
TAU-CAROTENE Pericarp-- -- *
ERIOCITRIN Pericarp-- -- Jim Duke's personal files.
SCUTELLAREIN Fruit Juice-- -- Jim Duke's personal files.
Activities (7)
Aldose-Reductase-Inhibitor IC56=10uM; IC10=1uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Antihemolytic
Antileukemic IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Antioxidant ED=uM
Antiviral IC50=10 uMEconomic & Medicinal Plant Research, 5: 225.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Phospholipase-A2-Inhibitor Somasundaram, S., Sadique, J. 1985. Anti-hemolytic Effect of Flavonoidal Glycosides of Clerodendron inerme: An in vitro Study. Fitoterapia 57(2): 103, 1986.
MUTATOCHROME Fruit-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
N-N-DIMETHYL-ANILINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOBILETIN Pericarp-- -- Jim Duke's personal files.
Activities (8)
Antiallergic
Antihistaminic ED=50 mg/kg
Antiproliferative IC70=8ug/ml
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cholinergic
Fungicide
Fungistat Weidenborner, M., Hindorf, H., Jha, H.C., and Tsotsonos, P. 1989. Antifungal Activity of Flavonoids Against Storage Fungi of the Genus Aspergillus. Phytochemistry. 29(4): 1103-1105.
Pesticide
HEPTULOSE Fruit-- -- *
SINENSETIN Fruit-- -- *
Activities (2)
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
ALPHA-COPAENE Pericarp Essent. Oil-- -- Jim Duke's personal files.
3-METHYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
LUTEOLIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Fruit-- -- Jim Duke's personal files.
FR Juice-- -- *
NEOXANTHIN-B Pericarp-- -- Jim Duke's personal files.
XYLOSYL-VITEXIN Leaf-- -- Jim Duke's personal files.
LIMONIN Twig-- -- Jim Duke's personal files.
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
AURAPTENOL Pericarp-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
EPOXY-NOOTKATONE Pericarp-- -- *
BETA-CITRAURIN Pericarp-- -- Jim Duke's personal files.
2-TRANS-O-FERULOYL-GLUCARIC-ACID Pericarp-- -- Jim Duke's personal files.
HESPERIDIN Flower-- -- Jim Duke's personal files.
Activities (31)
Analgesic
Anti-LDL
AntiDNA
AntiRNA
Antiallergenic Yakugaku Zasshi, 111: 193, 1991.
Antibradykinic Economic & Medicinal Plant Research, 5: 366.
Anticapillary-Fragility
Antiflu Economic & Medicinal Plant Research, 5: 197.
Antihistaminic
Antiinflammatory IC47=50 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antiinflammatory IC63=100 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antileukotriene
Antioxidant IC50=8 ppmPhytochemistry, 37: 1463.
Antiprostaglandin
Antistomatitic
Antitriglyceride
Antiulcer 100-150 mg/kg ipr
Antivaccinia Economic & Medicinal Plant Research, 5: 197.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Anxiolytic
CNS-Depressant 100-150 mg/kg ipr
Calcium-Antagonist IC50=1.2 uM rbt
Capillariprotective Martindale's 29th
Catabolic
Choleretic
Cyclooxygenase-Inhibitor
Hypolipidemic
Lipoxygenase-Inhibitor
Pesticide
ProHLDL
Vasopressor
VALENCENE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NARIRUTIN Pericarp-- -- Jim Duke's personal files.
Activities (1)
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
QUINIC-ACID Fruit-- -- *
Activities (1)
Choleretic Fitoterapia No.5-1986.
ZETA-CAROTENE-A Pericarp-- -- Jim Duke's personal files.
PHYTOFLUENE-A Pericarp-- -- Jim Duke's personal files.
ISOPENTENYL-PSORALENS Fruit-- -- *
CITRUNOBIN Root Bark-- -- *
TANGERETIN Fruit-- -- *
Activities (15)
Antiallergic
Antihistaminic ED=50 mg/kg
Antilymphocytic
Antimetastatic
Antimutagenic
Antioxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiproliferant IC70=8ug/ml
Apoptotic
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
ERK-1-Inhibitor
ERK-2-Inhibitor
Fungicide
Hypolipidemic
MDR-Inhibitor
Neuroprotective
ERIOCITRIN Flower-- -- Jim Duke's personal files.
ISORHOIFOLIN Flower-- -- Jim Duke's personal files.
N-N-DIMETHYL-3-METHYL-ANILINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOBILETIN Fruit Juice-- -- Jim Duke's personal files.
Activities (8)
Antiallergic
Antihistaminic ED=50 mg/kg
Antiproliferative IC70=8ug/ml
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cholinergic
Fungicide
Fungistat Weidenborner, M., Hindorf, H., Jha, H.C., and Tsotsonos, P. 1989. Antifungal Activity of Flavonoids Against Storage Fungi of the Genus Aspergillus. Phytochemistry. 29(4): 1103-1105.
Pesticide
3-HEPTYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOOTKATOL Fruit-- -- Jim Duke's personal files.
Activities (2)
Calcium-Antagonist 30 uM
Vasodilator Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
MALONIC-ACID Fruit-- -- *
Activities (1)
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
BETA-MYRCENE Fruit-- -- Jim Duke's personal files.
Activities (2)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Perfumery Merck 11th Edition
FLAVOXANTHIN Pericarp-- -- Jim Duke's personal files.
ACETIC-ACID Plant-- -- *
Activities (16)
Acidulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial 5,000 ppm
Antiotitic Martindale's 28th
Antisalmonella
Antivaginitic 1-2%
Expectorant Martindale's 28th
Fungicide Martindale's 29th
Keratitigenic
Mucolytic Martindale's 29th
Osteolytic
Perfumery FEMA 6,000-40,000 ppmAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Protisticide Martindale's 29th
Spermicide Martindale's 28th
Ulcerogenic HerbalGram No. 20, page 9.
Verrucolytic
NEOXANTHIN-A Pericarp-- -- Jim Duke's personal files.
XYLAN Fruit-- -- *
LIMONIN Branches-- -- Jim Duke's personal files.
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
ZEAXANTHIN Pericarp-- -- Jim Duke's personal files.
Activities (5)
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatoprotective
Quinone-Reductase-Inducer Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
DEACETYL-NOMILIN Seed-- -- Jim Duke's personal files.
BETA-APO-CAROTEN-8-AL Pericarp-- -- *
VALENCIACHROME Plant-- -- *
HESPERIDIN Fruit-- -- Jim Duke's personal files.
Activities (31)
Analgesic
Anti-LDL
AntiDNA
AntiRNA
Antiallergenic Yakugaku Zasshi, 111: 193, 1991.
Antibradykinic Economic & Medicinal Plant Research, 5: 366.
Anticapillary-Fragility
Antiflu Economic & Medicinal Plant Research, 5: 197.
Antihistaminic
Antiinflammatory IC47=50 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antiinflammatory IC63=100 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antileukotriene
Antioxidant IC50=8 ppmPhytochemistry, 37: 1463.
Antiprostaglandin
Antistomatitic
Antitriglyceride
Antiulcer 100-150 mg/kg ipr
Antivaccinia Economic & Medicinal Plant Research, 5: 197.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Anxiolytic
CNS-Depressant 100-150 mg/kg ipr
Calcium-Antagonist IC50=1.2 uM rbt
Capillariprotective Martindale's 29th
Catabolic
Choleretic
Cyclooxygenase-Inhibitor
Hypolipidemic
Lipoxygenase-Inhibitor
Pesticide
ProHLDL
Vasopressor
N-METHYL-TYRAMINE Pericarp-- -- Jim Duke's personal files.
Activities (1)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
NARINGIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Fruit-- -- *
PROPIONIC-ACID Plant-- -- *
Activities (6)
FLavor FEMA 1-36,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide 2,500-36,000
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery
Pesticide
Rubefacient Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
3-HYDROXY-5,8-EPOXY-5,8-DIHYDRO-8'-APO-BETA-CAROTEN-8'-AL Fruit Juice-- -- Jim Duke's personal files.
OSTHOL Root-- -- Jim Duke's personal files.
Activities (15)
5-Lipoxygenase-Inhibitor
Analgesic
Antiallergic
Antiinflammatory IC62 800 ppm orl
Antimalarial IC50=25.1 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Antimitotic 5-25 ug/mlGawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Antimutagenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Calcium-Antagonist IC50=4 ug/ml
Calcium-Antagonist 40 uM rat
Calcium-Antagonist 100 uM
Cancer-Preventive 5-25 ug/mlGawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Immunosuppressant
Juvabional
Pesticide
Xanthine-Oxidase-Inhibitor IC10=10 uM
ISOLUTEIN Pericarp-- -- Jim Duke's personal files.
BETA-ELEMENE Pericarp Essent. Oil-- -- Jim Duke's personal files.
Activities (5)
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antigliomic
Antiproliferant
Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Apoptotic
N-METHYL-ANILINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NICOTINIC-ACID-ETHYL-ESTER Pericarp Essent. Oil-- -- Jim Duke's personal files.
GLUCOSAN Fruit-- -- *
3-BUTYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
LOCHNOCARPOL-A Root-- -- Jim Duke's personal files.
MUTATOXANTHIN Pericarp-- -- Jim Duke's personal files.
NEOPONCIRIN Pericarp-- -- Jim Duke's personal files.
LIMONIN Bark-- -- Jim Duke's personal files.
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
ZEAXANTHIN Tissue Culture-- -- Jim Duke's personal files.
Activities (5)
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatoprotective
Quinone-Reductase-Inducer Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
DIOSMIN Pericarp-- -- *
Activities (34)
AntiCVI
Anticancer
Anticapillary-Fragility 300 mg/2x/day/womanMartindale's 28th
Anticarcinogenic
Anticlastogen
Anticytotoxic
Antiedemic 600 mg/kg ratNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiedemic 50-200 mg/kg/day
Antihemorrhoidal 450 mg 2x/day x7days then 1x/day x2months
Antihistaminic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiinflammatory 600 mg/kg rat
Antileukotriene
Antimelanomic
Antimetastatic
Antimetrorrhagic Fitoterapia No.55-1984.
Antioxidant
Antiperoxidant
Antiproliferant
Antiprostaglandin
Antiradicular
Antithromboxane
Antiulcer
COMT-Inhibitor 200-400 mg/kg ip
Chemopreventive
Cyclooxygenase-Inhibitor
Cytoprotective
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Hypoglycemic
Lipoxygenase-Inhibitor
MDR-Inhibitor 100 uMCritchfield, J. W., Welsh, C. J., Phang, J. M., Yeh, G. C. 1994. Modulation of Adriamycin Accumulation and Efflux by Flavonoids in HCT-15 Colon Cells. Activation of P-Glycoprotein as a Putative Mechanism. Biochem Pharmacol, 48(7): 1437-1445.
P450-Inhibitor
Radioprotective
Venoprotective
Venotonic
CYANIDIN-3-GLUCOSIDE Fruit-- -- *
BETA-APO-8'-CAROTINAL Pericarp-- -- Jim Duke's personal files.
2,4-TRANS,TRANS-O-FERULOYL-GLUCARIC-ACID Pericarp-- -- *
TANGERETIN Pericarp-- -- Jim Duke's personal files.
Activities (15)
Antiallergic
Antihistaminic ED=50 mg/kg
Antilymphocytic
Antimetastatic
Antimutagenic
Antioxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiproliferant IC70=8ug/ml
Apoptotic
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
ERK-1-Inhibitor
ERK-2-Inhibitor
Fungicide
Hypolipidemic
MDR-Inhibitor
Neuroprotective
NARINGIN Fruit-- -- *
Activities (12)
Aldose-Reductase-Inhibitor Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antidermatitic
Antiinflammatory
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antineuropathic Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antioxidant
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Myorelaxant Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
PONCITRIN Root-- -- Jim Duke's personal files.
5,8-EPOXY-5,8-DIHYDRO-10'-APO-BETA-CAROTEN-3,10'-DIOL Fruit Juice-- -- Jim Duke's personal files.
OBACUNONE-17-O-BETA-D-GLUCOSIDE Seed-- -- Jim Duke's personal files.
ISOCAPROIC-ACID Fruit-- -- *
ALPHA-SINESAL Pericarp-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DIOSMIN Flower-- -- Jim Duke's personal files.
Activities (34)
AntiCVI
Anticancer
Anticapillary-Fragility 300 mg/2x/day/womanMartindale's 28th
Anticarcinogenic
Anticlastogen
Anticytotoxic
Antiedemic 600 mg/kg ratNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiedemic 50-200 mg/kg/day
Antihemorrhoidal 450 mg 2x/day x7days then 1x/day x2months
Antihistaminic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiinflammatory 600 mg/kg rat
Antileukotriene
Antimelanomic
Antimetastatic
Antimetrorrhagic Fitoterapia No.55-1984.
Antioxidant
Antiperoxidant
Antiproliferant
Antiprostaglandin
Antiradicular
Antithromboxane
Antiulcer
COMT-Inhibitor 200-400 mg/kg ip
Chemopreventive
Cyclooxygenase-Inhibitor
Cytoprotective
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Hypoglycemic
Lipoxygenase-Inhibitor
MDR-Inhibitor 100 uMCritchfield, J. W., Welsh, C. J., Phang, J. M., Yeh, G. C. 1994. Modulation of Adriamycin Accumulation and Efflux by Flavonoids in HCT-15 Colon Cells. Activation of P-Glycoprotein as a Putative Mechanism. Biochem Pharmacol, 48(7): 1437-1445.
P450-Inhibitor
Radioprotective
Venoprotective
Venotonic
QUERCETAGETIN Fruit Juice-- -- Jim Duke's personal files.
Activities (8)
Aldose-Reductase-Inhibitor IC71=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor IC29=1 uM
AntiHIV
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Dye Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
HIV-RT-Inhibitor IC50=<1 ug/mlNakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Pesticide
OSTHOLE Root-- -- *
Activities (4)
Antimalarial
Calcium-Antagonist
Juvabional
Pesticide
APIGENIN-TRIMETHYL-ETHER Pericarp-- -- Jim Duke's personal files.
NARIRUTIN-GLUCOSIDE Pericarp-- -- Jim Duke's personal files.
GERANYL-OXY-PYRANOCOUMARIN Root-- -- Jim Duke's personal files.
SESLIN Root-- -- Jim Duke's personal files.
3-(BUT-TRANS-1-ENYL)-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
MUTATOXANTHIN Fruit Juice-- -- Jim Duke's personal files.
BRAYLIN Root-- -- Jim Duke's personal files.
5,8-EPOXY-5,8-DIHYDRO-8'-APO-BETA-CAROTEN-3,10-DIOL Fruit Juice-- -- *
DIOSMETIN-7-O-ALPHA-L-RHAMNO-GLUCOSIDE Leaf-- -- Jim Duke's personal files.
CRYPTOXANTHIN-5,5',6,6'-DIEPOXIDE Pericarp-- -- Jim Duke's personal files.
BERGAPTOL Fruit-- -- *
2'-TRANS-O-P-COUMAROYL-GLUCARIC-ACID Pericarp-- -- Jim Duke's personal files.
4-VINYL-GUAIACOL Fruit Juice-- -- Jim Duke's personal files.
Activities (4)
Antiedemic
Antiinflammatory
Antiprostaglandin
Prostaglandin-Synthesis-Inhibitor IC50=18 uM
TANGERETIN Fruit Juice-- -- Jim Duke's personal files.
Activities (15)
Antiallergic
Antihistaminic ED=50 mg/kg
Antilymphocytic
Antimetastatic
Antimutagenic
Antioxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiproliferant IC70=8ug/ml
Apoptotic
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
ERK-1-Inhibitor
ERK-2-Inhibitor
Fungicide
Hypolipidemic
MDR-Inhibitor
Neuroprotective
NARINGENIN-RUTINOSIDE-4-BETA-D-GLUCOSIDE Fruit-- -- *
POLYGALACTURONIC-ACID Fruit-- -- *
CAFFEIC-ACID Fruit Juice-- -- Jim Duke's personal files.
Activities (102)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allergenic
Analgesic
AntiHIV EC50=200 ug/ml
AntiLegionella
Antiadenoviral Economic & Medicinal Plant Research, 5: 207.
Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaging
Antiatherogenic
Antibacterial
Anticancer
Anticarcinogenic Economic & Medicinal Plant Research, 6: 189.
Antidepressant
Antiedemic Economic & Medicinal Plant Research, 6: 189.
Antielastase IC50=93 um/l
Antielastase IC50=86 ug/ml (475 uM)
Antiescherichic
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antigonadotropic Jim Duke's personal files.
Antihemolytic 25 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatoadenomic 200 ppm diet orl mus
Antihepatotoxic
Antiherpetic 50 ug/ml
Antiherpetic EC50=>50 ug/ml
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene
Antimelanogenic
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antiophidic
Antioxidant 50 uM
Antioxidant IC57=30 ppm
Antioxidant 1/3 quercetin
Antioxidant 30 mM
Antioxidant 1.3 x Vit. E
Antioxidant 1/2 BHA
Antiperoxidant IC50=44 uMPlanta Medica, 57: A54, 1991.
Antiperoxidant IC35=200 ug/ml
Antiperoxidant IC85=100 ug/ml
Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiprostaglandin
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 1/3 quercetin
Antiradicular 30 mM
Antiradicular IC50=32-35 uM
Antiseptic
Antispasmodic EC50=3.4-15 uMPhytotherapy Research, 4: 73.
Antistaphylococcic
Antistomatitic Economic & Medicinal Plant Research, 5: 207.
Antisunburn
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithyroid Jim Duke's personal files.
Antitumor 200 ppm diet orl mus
Antitumor (Skin)
Antitumor-Promoter IC42=10 uMCancer Research, 48: 5941.
Antiulcerogenic
Antivaccinia Economic & Medicinal Plant Research, 5: 207.
Antiviral IC50=62.5 ug/ml
Anxiolytic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
COX-2-Inhibitor IC32=100 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 2% (diet)
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Co-carcinogenic
Collagen-Sparing
Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Cytotoxic TC50=200 ug/ml
DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Fungicide MIC=0.4 mg/ml
Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol)
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.
Hepatotropic
Histamine-Inhibitor
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC27=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=62-148 uM
Lyase-Inhibitor IC50=94-164 uM
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Prooxidant
Prostaglandigenic
Sedative 500 mg
Sunscreen IC50=2.5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC91=5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC98=25 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Tumorigenic Jim Duke's personal files.
Vulnerary
Xanthine-Oxidase-Inhibitor IC50=39.21 uMMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
OBACUNONE-GLUCOSIDE Fruit Juice-- -- Jim Duke's personal files.
HYDROXYPROLINE Leaf-- -- Jim Duke's personal files.
Activities (1)
Vulnerary
NEOHESPERIDIN-DIHYDROCHALCONE Pericarp-- -- Jim Duke's personal files.
Activities (1)
Sweetener 1000-1500 x sucroseMerck 11th Edition
LIMONIN Root-- -- Jim Duke's personal files.
Activities (5)
Anticataleptic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Pesticide
XANTHYLETIN Root-- -- Jim Duke's personal files.
Activities (1)
DME-Inhibitor IC50=57.5 uMAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
SUBEROSIN Root-- -- Jim Duke's personal files.
CRYPTOXANTHIN-5,5',6,8'-DIEPOXIDE Pericarp-- -- Jim Duke's personal files.
5-HEXYL-2-METHYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
ANTHRANILIC-ACID-METHYL-ESTER Pericarp Essent. Oil-- -- Jim Duke's personal files.
NARIRUTIN-GLUCOSIDE Flower-- -- Jim Duke's personal files.
SESELIN Root-- -- Jim Duke's personal files.
Activities (3)
Antileukemic IC50=17.3 ug/ml
Fungicide
Pesticide
BETA-CITRAURIN Fruit Juice-- -- Jim Duke's personal files.
3-(4-METHYL-PHENYL)-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
NOMILIN Seed-- -- Jim Duke's personal files.
Activities (2)
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
LYCOPENE Pericarp-- -- Jim Duke's personal files.
Activities (16)
Anticancer (Bladder)
Anticancer (Breast)
Anticancer (Cervix)
Anticancer (Prostate)
Antioxidant
Antiprostatitic
Antiradicular
Antitumor
Antitumor (Bladder)
Antitumor (Breast)
Antitumor (Cervix)
Antitumor (Prostate)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Colorant
Hypocholesterolemic 60 mg/man/day/3 mos
Prooxidant 20 ug/g
OCTADECADIENOIC-ACID Pericarp-- -- Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
5,8-EPOXY-5,5',8-TETRAHYDRO-BETA,BETA-CAROTEN-3,3',5',6'-TETROL Plant-- -- *
CRYPTOXANTHIN Fruit-- -- *
Activities (2)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Vitamin-A-Activity
2'-TRANS-O-P-COUMAROYL-GALACTARIC-ACID Pericarp-- -- Jim Duke's personal files.
2,4-TRANS-TRANS-O-DIFERULOYL-GLUCARIC-ACID Pericarp-- -- Jim Duke's personal files.
SYNEPHRINE Pericarp-- -- Jim Duke's personal files.
Activities (5)
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiovascular 0.25 mg/kg ivn dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Hypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Oxytocic 2.5 mg/kg ivn musBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Vasoconstrictor Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
NARINGENIN-RUTINOSIDE Fruit-- -- *
DELTA-CADINENE Pericarp Essent. Oil-- -- Jim Duke's personal files.
Activities (9)
Aldose-Reductase-Inhibitor
Antiacne
Antibacterial MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antistreptococcic
Cytochrome-P450-Inducer
P450-Inducer
Pesticide
Testosterone-Inducer
EPOXY-NOOTKATONE Pericarp Essent. Oil-- -- Jim Duke's personal files.
VITEXIN-XYLOSIDE Fruit-- -- Jim Duke's personal files.
D-LIMONENE Fruit Juice-- -- Jim Duke's personal files.
Activities (19)
Antiacetylcholinesterase IC22=1.2 mM
Anticancer (Breast) 8,000 mg/kg
Anticancer (Gastric)
Antimelanomic IC50=450 uM/l
Antitumor (Breast) 8,000 mg/kg
Antitumor (Gastric)
Antitumor-Promoter
Apoptotic 8,000 mg/kg
Cancer-Preventive
Chemopreventive
Differentiator 8,000 mg/kg
FLavor FEMA 30-2,300Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic
Insecticide
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Litholytic Martindale's 28th
Nephrotoxic
P450-2B1-Inhibitor IC50=0.19 uM
Pesticide
XANTHOXYLETIN Root-- -- Jim Duke's personal files.
Activities (1)
Anticonvulsant
DIHYDROKAEMPFEROL-4'-METHYL-ETHER-7-O-RHAMNOSIDE Fruit-- -- Jim Duke's personal files.
ALPHA-PINENE Plant-- -- *
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
BETA-CRYPTOXANTHIN Fruit-- -- *
Activities (2)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Vitamin-A-Activity
5-ACETYL-2-METHYL-PYRIDINE Pericarp Essent. Oil-- -- Jim Duke's personal files.
MERANZINE Fruit-- -- *
ANTHERAXANTHIN Tissue Culture-- -- Jim Duke's personal files.
Activities (1)
Colorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NARIRUTIN Fruit Juice-- -- Jim Duke's personal files.
Activities (1)
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
CITFLAVANONE Root Bark-- -- *
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.