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ActivityReference
Acaricide
Chemicals (1)
MENTHONE
ACE-Inhibitor
Chemicals (1)
ALPHA-TERPINEOL 100 ug/ml (weak activity)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Chemicals (1)
PULEGONE
Aldose-Reductase-Inhibitor Okamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Chemicals (1)
ALPHA-TERPINEOL 100 ug/ml
Allelochemic
Chemicals (1)
ALPHA-PINENE
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Chemicals (2)
ALPHA-TERPINEOL
MENTHONE
Allergenic Martindale's 29th
Chemicals (3)
ALPHA-PINENE
BETA-PINENE
MENTHOL
Analgesic
Chemicals (3)
MENTHOL
MENTHONE
P-CYMENE
Anesthetic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL 2,000 ppm
Antiacetylcholinesterase
Chemicals (7)
D-LIMONENE IC22=1.2 mM
ISOMENTHONE IC50=1.6 mM
MENTHOL IC50=2.0 mM
MENTHONE IC50=1.4 mM
P-CYMENE IC40=1.2 mM
PIPERITENONE IC50=110 ug/ml
PULEGONE IC50=0.9 mM
Antiacne
Chemicals (2)
ALPHA-PINENE
ALPHA-TERPINEOL
Antiaggregant
Chemicals (2)
MENTHOL IC50=750
MENTHONE IC50=750
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Chemicals (2)
MENTHOL
MENTHONE
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Chemicals (1)
PULEGONE
Antiasthmatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Chemicals (1)
MENTHOL
Antibacillary
Chemicals (2)
MENTHONE MIC=1.25 mg/ml
P-CYMENE
Antibacillus
Chemicals (1)
MENTHOL MIC=1.25 mg/ml
Antibacterial
Chemicals (6)
ALPHA-PINENE
ALPHA-TERPINEOL MIC=800-1,600 ug/ml
MENTHOL MIC=0.625-2.5
MENTHONE MIC=0.625-5 mg/ml
P-CYMENE
PULEGONE
Antibronchitic Martindale's 28th
Chemicals (1)
MENTHOL
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Chemicals (1)
ALPHA-TERPINEOL
Anticancer (Breast)
Chemicals (1)
D-LIMONENE 8,000 mg/kg
Anticancer (Gastric)
Chemicals (1)
D-LIMONENE
Anticariogenic Muroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Chemicals (1)
ALPHA-TERPINEOL MIC=800-1,600 ug/ml
Anticholinesterase Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Chemicals (1)
PULEGONE
Antidandruff A.L.L. Hunting. Encyclopedia of Shampoo Ingredients. Micelle Press, Cranford NJ. 467 pp.
Chemicals (1)
MENTHOL
Antiescherichic
Chemicals (2)
MENTHOL MIC=1.25 mg/ml
MENTHONE MIC=5 mg/ml
Antifeedant
Chemicals (1)
ALPHA-PINENE
Antiflu
Chemicals (2)
ALPHA-PINENE
P-CYMENE
Antihalitosic American Health, 12(4): 17, 1993.
Chemicals (1)
MENTHOL
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Chemicals (3)
MENTHOL
MENTHONE
PULEGONE
Antiinflammatory
Chemicals (4)
ALPHA-PINENE 500 mg/kg
ALPHA-TERPINEOL
BETA-PINENE
MENTHOL
Antilisteria
Chemicals (2)
MENTHOL MIC=0.625 mg/ml
MENTHONE MIC=1.25 mg/ml
Antimelanomic
Chemicals (1)
D-LIMONENE IC50=450 uM/l
Antineuralgic
Chemicals (1)
MENTHOL
Antiodontalgic Martindale's 28th
Chemicals (1)
MENTHOL
Antioxidant
Chemicals (1)
ISOMENTHONE
Antipneumonic
Chemicals (1)
ALPHA-PINENE
Antiproliferant
Chemicals (1)
ALPHA-TERPINEOL
Antipruritic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
Antipyretic
Chemicals (2)
MENTHOL
PULEGONE
Antiradicular
Chemicals (1)
ISOMENTHONE
Antirheumatalgic Martindale's 28th
Chemicals (1)
P-CYMENE
Antirheumatic Martindale's 28th
Chemicals (1)
MENTHOL
Antisalmonella
Chemicals (2)
MENTHOL MIC=0.625 mg/ml
MENTHONE MIC=5 mg/ml
Antiseptic Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Chemicals (5)
ALPHA-PINENE
ALPHA-TERPINEOL
BETA-PINENE
MENTHOL 4 x phenol
MENTHONE 2.25 x phenol
Antisinusitic Martindale's 28th
Chemicals (1)
MENTHOL
Antispasmodic
Chemicals (4)
ALPHA-PINENE
BETA-PINENE
MENTHOL ED50=0.01 mg/ml
MENTHONE ED50=0.044 mg/ml
Antistaphylococcic
Chemicals (3)
ALPHA-PINENE
MENTHOL MIC=0.625 mg/ml
MENTHONE MIC=0.625-2.5 mg/ml
Antistreptococcic
Chemicals (1)
MENTHOL MIC=0.4 mg/ml
Antitartar
Chemicals (1)
MENTHOL
Antitumor (Breast)
Chemicals (1)
D-LIMONENE 8,000 mg/kg
Antitumor (Gastric)
Chemicals (1)
D-LIMONENE
Antitumor-Promoter
Chemicals (1)
D-LIMONENE
Antivaginitic
Chemicals (1)
MENTHOL
Antiviral
Chemicals (2)
ALPHA-PINENE
P-CYMENE
Antivulvitic
Chemicals (1)
MENTHOL
Apoptotic
Chemicals (1)
D-LIMONENE 8,000 mg/kg
Avifuge
Chemicals (1)
PULEGONE
Bradycardic Martindale's 28th
Chemicals (1)
MENTHOL 65 mg/3 x day/woman
Bronchomucolytic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
Chemicals (1)
MENTHOL
Bronchomucotropic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
Bronchorrheic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
Chemicals (1)
MENTHOL
Calcium-Antagonist
Chemicals (1)
MENTHOL
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Chemicals (4)
ALPHA-PINENE
D-LIMONENE
MENTHONE
PULEGONE
Candidicide
Chemicals (4)
BETA-PINENE
MENTHOL MIC=0.625 mg/ml
MENTHONE MIC=2.5 mg/ml
PULEGONE
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
Cerebrotoxic J. Aromatherapy 4: 24.
Chemicals (2)
MENTHONE orl man
PULEGONE orl man
Chemopreventive
Chemicals (1)
D-LIMONENE
Choleretic
Chemicals (1)
MENTHOL
Cicatrizant
Chemicals (1)
ALPHA-TERPINEOL ED50=240 ug/g mus
Ciliotoxic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
CNS-Depressant
Chemicals (1)
MENTHOL
CNS-Stimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Chemicals (1)
MENTHOL
Coleoptophile
Chemicals (1)
ALPHA-PINENE
Congestant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Chemicals (1)
MENTHOL
Counterirritant
Chemicals (1)
MENTHOL
Culicide
Chemicals (1)
MENTHONE LC50=156-194 mg/l
Decongestant? Eccles, R., et al. 1989. The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. J. Pharm. Pharmacol. 42: 652-654, 1990.
Chemicals (1)
MENTHOL 11 mg/man
Dermatitigenic
Chemicals (1)
MENTHOL
Diaphoretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Chemicals (1)
MENTHOL
Differentiator
Chemicals (1)
D-LIMONENE 8,000 mg/kg
Encephalopathic Lawrence Review of Natural Products, Jan-92.
Chemicals (1)
PULEGONE 80 mg/kg orl rat
Enterorelaxant J. Aromatherapy 4: 22.
Chemicals (1)
MENTHOL
Expectorant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (2)
ALPHA-PINENE
MENTHOL
FLavor Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Chemicals (7)
ALPHA-PINENE FEMA 15-150
ALPHA-TERPINEOL FEMA 5-40
BETA-PINENE FEMA 15-600
D-LIMONENE FEMA 30-2,300
MENTHONE FEMA 5-50
P-CYMENE FEMA 12-250
PULEGONE FEMA 5-30
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Chemicals (3)
MENTHONE
P-CYMENE
PULEGONE
Gastrosedative Merck 11th Edition
Chemicals (1)
MENTHOL
Glutathionalytic Lawrence Review of Natural Products, Jan-92.
Chemicals (1)
PULEGONE
Hallucinogenic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Chemicals (1)
PULEGONE
Hepatotoxic Lewis, E.J. and Friedrich, E.C. 1989. The Essential Oil of Poliomintha incana. Planta Medica 56(2): 224-226, 1990.
Chemicals (1)
PULEGONE
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Chemicals (4)
ALPHA-PINENE IC50=30 uM
BETA-PINENE
P-CYMENE IC50=50 uM
PULEGONE IC50=1.5 uM
Hypocholesterolemic
Chemicals (1)
D-LIMONENE
Insecticide Shah, G.C., Bhandari, R. & Mathela, C.S. 1992. 1,2-Epoxy-p-Menthane Derivatives from some Labiatae Species. J. Ess. Oil Res. 4: 57-59.
Chemicals (6)
ALPHA-PINENE 0.82 uM/fly
ALPHA-TERPINEOL 1.29 uM/fly
D-LIMONENE
MENTHONE LC50=156-194 mg/l
PIPERITENONE-OXIDE
PULEGONE
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Chemicals (5)
ALPHA-PINENE 50 ppm
BETA-PINENE
D-LIMONENE
P-CYMENE
PULEGONE
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Chemicals (1)
ALPHA-PINENE
Interleukin-6-Inhibitor
Chemicals (1)
ALPHA-TERPINEOL
Irritant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (4)
ALPHA-PINENE
BETA-PINENE
MENTHOL
P-CYMENE
Larvicide
Chemicals (1)
MENTHONE LC50=156-194 mg/l
Laxative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Chemicals (1)
P-CYMENE
Litholytic Martindale's 28th
Chemicals (1)
D-LIMONENE
Mosquitofuge
Chemicals (1)
ALPHA-TERPINEOL > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Chemicals (1)
ALPHA-TERPINEOL
Mutagenic
Chemicals (1)
MENTHONE
Myorelaxant Martindale's 29th
Chemicals (1)
MENTHOL
Nematicide Shoyakugaku Zasshi, 44: 183.
Chemicals (3)
ALPHA-TERPINEOL MLC=1 mg/ml
MENTHOL MLC=1 mg/ml
MENTHONE MLC=1 mg/ml
Nephrotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Chemicals (2)
D-LIMONENE
PULEGONE
Neurodepressant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
Neuropathogenic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL 40-100 mg/day/rat
Neurotoxic
Chemicals (1)
PULEGONE
Nociceptive Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
P450-2B1-Inhibitor
Chemicals (2)
ALPHA-PINENE IC50=0.087 uM
D-LIMONENE IC50=0.19 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Chemicals (7)
ALPHA-PINENE
ALPHA-TERPINEOL
BETA-PINENE
MENTHOL
MENTHONE
PIPERITENONE
PULEGONE
Pesticide
Chemicals (9)
ALPHA-PINENE
ALPHA-TERPINEOL
BETA-PINENE
D-LIMONENE
MENTHOL
MENTHONE
P-CYMENE
PIPERITENONE-OXIDE
PULEGONE
Psychoactive
Chemicals (1)
MENTHONE
Pulifuge
Chemicals (1)
PULEGONE
Pulmonotoxic
Chemicals (1)
PULEGONE
Refrigerant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Chemicals (1)
MENTHOL
Rubefacient
Chemicals (1)
MENTHOL
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Chemicals (5)
ALPHA-PINENE
ALPHA-TERPINEOL
MENTHONE
P-CYMENE
PULEGONE
Spasmogenic
Chemicals (2)
ALPHA-PINENE
BETA-PINENE
Termiticide
Chemicals (2)
ALPHA-TERPINEOL IC100=5 mg/g
MENTHOL
Toxic Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Chemicals (1)
PIPERITENONE 10,000/man
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Chemicals (1)
ALPHA-PINENE
Transdermal
Chemicals (4)
ALPHA-PINENE
ALPHA-TERPINEOL
BETA-PINENE
MENTHOL
Trichomonicide
Chemicals (2)
MENTHONE LD100=600 ug/ml
P-CYMENE LD100=50 ug/ml
Vibriocide
Chemicals (1)
MENTHOL
Vulnerary
Chemicals (1)
ALPHA-TERPINEOL ED50=240 ug/g mus
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.