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Activities: 157
All Chemicals: 30
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Chemical Low PPM High PPM StdDev *Reference
EO Shoot2100.0 2300.0 -0.74 Tucker, et al, EB46(1):21-24.1992
1,8-CINEOLE Shoot425.0 565.0 -0.13 Tucker, et al, EB46(1):21-24.1992
Activities (67)
(-)-Chronotropic 87 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 87 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Acaricide LC100=6 uM
Allelopathic
Allergenic
Anesthetic
Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiacetylcholinesterase IC50=41 ug/ml
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacterial 50 ppm
Antibronchitic
Anticariogenic
Anticatarrh Martindale's 29th
Anticholinesterase IC50=50-70
Antifatigue
Antihalitosic American Health, 12(4): 17, 1993.
Antiinflammatory
Antilaryngitic
Antinociceptive
Antipharyngitic
Antiplaque
Antirheumatic
Antirhinitic
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antisinusitic
Antispasmodic
Antistaphylococcic 50 ppm
Antitussive
Antiulcer
CNS-Stimulant
Candidicide
Carcinogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Choleretic
Convulsant
Counterirritant Martindale's 29th
Cytochrome-P450-Inducer
Decongestant
Degranulant 0.3 ul/ml
Dentifrice Martindale's 29th
Edemagenic inj
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 1-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective
Gram(+)icide
Gram(-)icide
Hepatotonic
Herbicide IC50=78 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypotensive
Inflammatory inj
Insectifuge
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Neurotoxic
P450-Inducer
Pediculicide 2.3 x pyrethrin
Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Rubefacient Martindale's 29th
Secretogogue
Sedative
Spasmogenic
Surfactant
Testosterone-Hydroxylase-Inducer
Transdermal
Trichomonicide LD100=1,000 ug/ml
SABINENE Shoot235.0 340.0 0.07 Tucker, et al, EB46(1):21-24.1992
Activities (5)
Antibacterial
Antihelicobacter
Antiseptic
Antiulcer
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
TERPINEN-4-OL Shoot195.0 250.0 -0.06 Tucker, et al, EB46(1):21-24.1992
Activities (23)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacetylcholinesterase IC21-24=1.2 mM
Antiacne
Antiallergic
Antiasthmatic Chin. J. Tuber. Respir. Dis., 4:203, 1982.
Antibacterial
Antioxidant
Antiseptic Flav. & Frag. J. 9: 129.
Antispasmodic
Antitussive Chin. J. Tuber. Respir. Dis.
Antiulcer
Bacteriostatic Chin. J. Tuber. Respir. Dis.
Diuretic 0.1 ml/rat
Fungicide
Herbicide IC50=200 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=22 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge
Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Renoirritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Spermicide ED100=0.015
Vulnerary Lawrence Review of Natural Products, Jan-91.
GAMMA-TERPINENE Shoot170.0 225.0 -0.24 Tucker, et al, EB46(1):21-24.1992
Activities (11)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC23=1.2 mM
Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Antioxidant Jim Duke's personal files.
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
ALPHA-TERPINYL-ACETATE Shoot130.0 185.0 -0.22 Tucker, et al, EB46(1):21-24.1992
NERYL-ACETATE Shoot145.0 165.0 2.45 Tucker, et al, EB46(1):21-24.1992
Activities (5)
Antiflu
Antiviral
FLavor FEMA 1-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
ALPHA-PINENE Shoot90.0 140.0 -0.13 Tucker, et al, EB46(1):21-24.1992
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
BETA-PINENE Shoot80.0 110.0 -0.11 Tucker, et al, EB46(1):21-24.1992
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
ALPHA-TERPINENE Shoot60.0 75.0 -0.27 Tucker, et al, EB46(1):21-24.1992
Activities (13)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC50=1.0 mM
Antinitrosaminic
Antispasmodic
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 0.86 uM/fly
Insectifuge
P450-2B1-Inhibitor IC50=0.76 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic
MYRCENE Shoot40.0 50.0 -0.29 Tucker, et al, EB46(1):21-24.1992
Activities (22)
ACE-Inhibitor 100 ug/ml
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allergenic
Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antibacterial
Anticonvulsant
Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antinitrosaminic
Antinociceptive 10-20 mg/kg ipr musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antinociceptive 20-40 mg/kg scu musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antioxidant Jim Duke's personal files.
Antispasmodic Jim Duke's personal files.
Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMA 0.5-9Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypothermic
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Myorelaxant 100-200 mg/kg
P450-2B1-Inhibitor IC50=0.14 uM
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
CARVONE Shoot20.0 50.0 -0.25 Tucker, et al, EB46(1):21-24.1992
Activities (19)
Allergenic
Antiacetylcholinesterase IC50=1.4-1.8 mM
Antiproliferative
Antiseptic 1.5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
FLavor FEMA 80-3,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Trichomonicide LD100=300 ug/ml
Vermicide
P-CYMENE Shoot30.0 40.0 -0.47 Tucker, et al, EB46(1):21-24.1992
Activities (16)
Analgesic Martindale's 28th
Antiacetylcholinesterase IC40=1.2 mM
Antibacillary
Antibacterial
Antiflu
Antirheumatalgic Martindale's 28th
Antiviral
FLavor FEMA 12-250Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Herbicide IC50=50 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Laxative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide LD100=50 ug/ml
(E)-SABINENE-HYDRATE Shoot25.0 35.0 Tucker, et al, EB46(1):21-24.1992
TERPINOLENE Shoot30.0 35.0 0.21 Tucker, et al, EB46(1):21-24.1992
Activities (9)
Allelochemic
Antifeedant
Antinitrosaminic
Antioxidant
Deodorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 15-60Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
LIMONENE Shoot25.0 30.0 -0.31 Tucker, et al, EB46(1):21-24.1992
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
GERANYL-ACETATE Shoot20.0 30.0 -0.46 Tucker, et al, EB46(1):21-24.1992
Activities (5)
Allergenic
FLavor FEMA 1-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sedative Jim Duke's personal files.
CARYOPHYLLENE-OXIDE Shoot4.0 27.0 -0.34 Tucker, et al, EB46(1):21-24.1992
Activities (8)
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Calcium-Antagonist ED50=32 uM gpg
Fungicide
Insecticide Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Pesticide
(Z)-SABINENE-HYDRATE Shoot15.0 20.0 Tucker, et al, EB46(1):21-24.1992
BETA-BISABOLENE Shoot3.0 20.0 -0.53 Tucker, et al, EB46(1):21-24.1992
Activities (6)
Abortifacient
Antirhinoviral IC50=1,800?Denyer, C.V., Jackson, P., Loakes, D.M., Ellis, M.R., and Yound, D.A.B. Isolation of Antirhinoviral Sesquiterpenes From Ginger (Zingiber officinale). Journal of Natural Products, 57(5): 658-662, 1994.
Antiulcer IC57=100 mg/kgYamahara, J., et al. Stomachic principles in ginger. II. Pungent and anti-ulcer effects of low polar constituents isolated from ginger, the dried rhizoma of... Yakugaku Zasshi 112: 645-655 (1992).
Antiviral IC50=1,800?Denyer, C.V., Jackson, P., Loakes, D.M., Ellis, M.R., and Yound, D.A.B. Isolation of Antirhinoviral Sesquiterpenes From Ginger (Zingiber officinale). Journal of Natural Products, 57(5): 658-662, 1994.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Stomachic
LINALYL-FORMATE Shoot5.0 20.0 -1.0 Tucker, et al, EB46(1):21-24.1992
Activities (2)
FLavor FEMA 1-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
LINALOL Shoot5.0 20.0 -0.22 Tucker, et al, EB46(1):21-24.1992
ALPHA-TERPINEOL Shoot1.0 15.0 -0.27 Tucker, et al, EB46(1):21-24.1992
Activities (23)
ACE-Inhibitor 100 ug/ml (weak activity)
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacne
Antibacterial MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antiinflammatory
Antiproliferant
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cicatrizant ED50=240 ug/g mus
FLavor FEMA 5-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 1.29 uM/fly
Interleukin-6-Inhibitor
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide IC100=5 mg/g
Transdermal
Vulnerary ED50=240 ug/g mus
ALPHA-HUMULENE Shoot10.0 15.0 -0.28 Tucker, et al, EB46(1):21-24.1992
Activities (2)
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
2-UNDECANONE Shoot10.0 15.0 Tucker, et al, EB46(1):21-24.1992
Activities (4)
Anthelmintic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Hirudicide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Nematicide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Pesticide
TRANS-CINNAMYL-ACETATE Shoot7.0 13.0 Tucker, et al, EB46(1):21-24.1992
CAMPHENE Shoot2.0 4.0 -0.13 Tucker, et al, EB46(1):21-24.1992
Activities (9)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Jim Duke's personal files.
Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
FLavor FEMA 15-175Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Spasmogenic Fitoterapia No.59-1984.
GERANIOL Shoot2.0 3.0 -0.51 Tucker, et al, EB46(1):21-24.1992
Activities (35)
Allergenic
Anthelmintic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antibacterial MIC=400 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antibacterial MIC=64 ug/ml
Antibacterial MBC=800 ug/ml
Anticancer (Pancreas) IC50=265 uM
Anticariogenic MIC=400 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antimelanomic IC50=150 uM/l
Antisalmonella MIC=400 ug/ml
Antiseptic 7 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiseptic MIC=64 ug/ml
Antiseptic 400-800 ug/ml
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antitubercular MIC=64 ug/ml
Antitumor Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147.
Antitumor (Pancreas) IC50=265 uM
Ascaricide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Embryotoxic
Emetic 3 x ipecacLawrence Review of Natural Products, Sep-97.
Expectorant Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
FLavor FEMA 1-10Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide IC93=2 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC100-2,000 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge 50 ppm
Insectiphile Merck 11th Edition
Mycobactericide MIC=64 ug/ml
Nematicide IC86=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Nematicide MLC=1,000 ug/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Sedative
Trichomonicide LD100=300 ug/ml
N-PROPYL-2-METHYL-BUTYRATE Shoot1.0 2.0 Tucker, et al, EB46(1):21-24.1992
2-NONANONE Shoot-- 2.0 Tucker, et al, EB46(1):21-24.1992
Activities (2)
Antiseptic
Pesticide
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.