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All Chemicals: 28
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Chemical Low PPM High PPM StdDev *Reference
6-METHOXYCATALPOL Root-- 55.0 De Sandos, J., Fernandez, L., Diaz, A. M., Rubio, B., Ollivier, E., Faure, R., Balansard, G. 1998. Catalpol Glycosides from Scrophularia scorodonia. Pharmazie, 53(6): 427-428.
6-O-ALPHA-L-[3''-O-TRANS-P-COUMAROYL]-RHAMNOPYRANOSYLCATALPOL Flower-- 27.0 De Sandos, J., Fernandez, L., Diaz, A. M., Rubio, B., Ollivier, E., Faure, R., Balansard, G. 1998. Catalpol Glycosides from Scrophularia scorodonia. Pharmazie, 53(6): 427-428.
8-ACETYLHARPAGIDE Plant-- -- Benito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
Activities (1)
Antiinflammatory IC50=19.5 uMBenito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
8-O-ACETYLHARPAGIDE Leaf-- 0.002 Fernandez-Matellano, L., Ollivier, E., Diaz-Lanza, A. M., Faure, R., Balansard, G. 1995. Iridoids from Scrophularia scorodonia. Planta Medica, 61(1): 93.
Activities (1)
Cytotoxic ED50=>200-425 uM
8-O-ACETYLHARPAGIDE Plant-- -- Fernandez, L., Martin, T., Villaescusa, L., Bartolome, C., Rubio, B., Diaz, A. M. 1995. Rosmarinic Acid and Iridoids of Scrophularia scorodonia L. Colloq Inst Natl Rech Agron, 69: 307-308.
Activities (1)
Cytotoxic ED50=>200-425 uM
8-O-CIS-CINNAMOYLHARPAGIDE Shoot-- 0.001 Fernandez, L., Diaz, A. M., Ollivier, E., Faure, R., Balansard, G. 1995. An Iridoid Diglycoside Isolated from Scrophularia scorodonia. Phytochemistry, 40(5): 1569-1571.
AUCUBIN Plant-- -- Benito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
Activities (20)
Antibacterial
Antidote (Amanitin) 200 mg/kg ipr musAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 276.
Antiedemic 1/2 indomethacinBruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antiinflammatory IC50=12-72 uM
Antiinflammatory 1/2 indomethacin
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antioxidant
Antiprolactin
Antistaphylococcic
Candidicide
Cathartic ED50=390 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Collagenic
Diuretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatoprotective
Lactagogue Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Laxative Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Paralytic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Pesticide
RNA-Inhibitor Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 275.
Uricosuric Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
AUCUBOSIDE Leaf-- 35.0 Fernandez-Matellano, L., Ollivier, E., Diaz-Lanza, A. M., Faure, R., Balansard, G. 1995. Iridoids from Scrophularia scorodonia. Planta Medica, 61(1): 93.
BARTSIOSIDE Plant-- -- Benito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
Activities (1)
Antiinflammatory IC50=4.3 uMBenito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
BARTSIOSIDE Leaf-- 30.0 Fernandez-Matellano, L., Ollivier, E., Diaz-Lanza, A. M., Faure, R., Balansard, G. 1995. Iridoids from Scrophularia scorodonia. Planta Medica, 61(1): 93.
Activities (1)
Antiinflammatory IC50=4.3 uMBenito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
BUDDLEJASAPONIN Flower-- 4000.0 Emam, A. M., Diaz-Lanza, A. M., Matellano-Fernandez, L., Faure, R., Moussa, A. M. Balansard, G. 1997. Biological Activities of Buddlejasaponin Isolated from Buddleja madagascarienis and Scrophularia scorodonia. Pharmazie, 52(1): 76-77.
HARPAGIDE Plant-- -- Benito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
Activities (6)
(-)-Chronotropic
(-)-Inotropic
Analgesic
Antiarthritic
Antiinflammatory Planta Medica, 55(7): 626.
Calcium-Antagonist Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
HARPAGOSIDE Plant-- -- *
Activities (6)
(+)-Inotropic
(-)-Chronotropic
Analgesic Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiarrhythmic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiinflammatory IC50=10 uM
Calcium-Antagonist Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
HARPAGOSIDE Flower-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
Activities (6)
(+)-Inotropic
(-)-Chronotropic
Analgesic Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiarrhythmic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiinflammatory IC50=10 uM
Calcium-Antagonist Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
HARPAGOSIDE Stem-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
Activities (6)
(+)-Inotropic
(-)-Chronotropic
Analgesic Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiarrhythmic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiinflammatory IC50=10 uM
Calcium-Antagonist Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
HARPAGOSIDE Leaf-- 2072.0 *
Activities (6)
(+)-Inotropic
(-)-Chronotropic
Analgesic Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiarrhythmic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiinflammatory IC50=10 uM
Calcium-Antagonist Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
ROSMARINIC-ACID Plant-- -- Fernandez, L., Martin, T., Villaescusa, L., Bartolome, C., Rubio, B., Diaz, A. M. 1995. Rosmarinic Acid and Iridoids of Scrophularia scorodonia L. Colloq Inst Natl Rech Agron, 69: 307-308.
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
SACCATOSIDE Flower-- 29.0 De Sandos, J., Fernandez, L., Diaz, A. M., Rubio, B., Ollivier, E., Faure, R., Balansard, G. 1998. Catalpol Glycosides from Scrophularia scorodonia. Pharmazie, 53(6): 427-428.
SCORODIOSIDE Plant-- -- Benito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
SCORODIOSIDE Stem-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
SCORODIOSIDE Leaf-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
SCORODIOSIDE Shoot-- 61.0 Fernandez, L., Diaz, A. M., Ollivier, E., Faure, R., Balansard, G. 1995. An Iridoid Diglycoside Isolated from Scrophularia scorodonia. Phytochemistry, 40(5): 1569-1571.
SCROPOLIOSIDE-B Root-- 38.0 De Sandos, J., Fernandez, L., Diaz, A. M., Rubio, B., Ollivier, E., Faure, R., Balansard, G. 1998. Catalpol Glycosides from Scrophularia scorodonia. Pharmazie, 53(6): 427-428.
SCROPOLIOSIDE-B Plant-- -- Benito, P. B., Lanza, A. M. D., Sen, A. M. S., Galindez, J. D., Matellano, L. F., Gomez, A. S., Martinez, M. J. A. 2000. Effects of some iridoids from plant origin on arachidonic acid metabolism in cellular systems. Planta Medica, 66(4): 324-328.
SYRINGIN Stem-- -- *
Activities (9)
ACE-Inhibitor
Adaptogenic
Anticomplementary
Antipyretic
Antistress
Immunomodulator
Immunostimulant
Neurotropic
Tonic
VERBASCOSIDE Flower-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
Activities (20)
Aldose-Reductase-Inhibitor IC50=0.39-15.1 uM
Analgesic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial
Antifeedant
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihypertensive Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic ED50=2.6 ug/ml
Antioxidant ED50=1 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antiseptic
Antistaph
Antitumor
Cytotoxic ED50=2.6 ug/ml
Fungicide MIC=0.4 mg/ml
Hypertensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunosuppressant
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PKC-Inhibitor
Pesticide
Phytoalexin
VERBASCOSIDE Stem-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
Activities (20)
Aldose-Reductase-Inhibitor IC50=0.39-15.1 uM
Analgesic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial
Antifeedant
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihypertensive Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic ED50=2.6 ug/ml
Antioxidant ED50=1 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antiseptic
Antistaph
Antitumor
Cytotoxic ED50=2.6 ug/ml
Fungicide MIC=0.4 mg/ml
Hypertensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunosuppressant
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PKC-Inhibitor
Pesticide
Phytoalexin
VERBASCOSIDE Leaf-- -- Diaz, A., et al. 1998. Reverse-Phase High Pressure Liquid Chromatographic Analysis of Harpagoside, Scorodioside and Verbascoside from Scrophularia scorodonia: Quantitative Determination of Harpagoside. Planta Medica, 64(1): 94-95.
Activities (20)
Aldose-Reductase-Inhibitor IC50=0.39-15.1 uM
Analgesic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial
Antifeedant
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihypertensive Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic ED50=2.6 ug/ml
Antioxidant ED50=1 uMSeidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antiseptic
Antistaph
Antitumor
Cytotoxic ED50=2.6 ug/ml
Fungicide MIC=0.4 mg/ml
Hypertensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunosuppressant
Lipoxygenase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PKC-Inhibitor
Pesticide
Phytoalexin
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.