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Activities: 246
All Chemicals: 97
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Chemical Low PPM High PPM StdDev *Reference
(-)-EPICATECHIN Bark-- 25.0 1.0 *
Activities (38)
5-Lipoxygenase-Inhibitor IC50=22-50 uM/l
ACE-Inhibitor IC50=0.216 mM/l
ACE-Inhibitor 0.5 mg/ml rbt (weak activity)
Allelochemic Hanke, F. J., Natural Products as a Resource for Biologically Active Compounds, Thesis, U. Cal (Santa Cruz), 1986, 252 pp
AntiEBV Economic & Medicinal Plant Research, 6: 189.
AntiHIV EC50=2 ug/ml
Antiaggregant
Antianaphylactic
Antibacterial
Antidiabetic 30 mg/kg rat
Antihepatitic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihyperglycemic
Antiinflammatory
Antileukemic Economic & Medicinal Plant Research, 6: 189.
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antioxidant IC50=6.3 ug/ml
Antiperoxidant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral EC50=2 ug/ml
Beta-Adrenergic Receptor Blocker 10 uMZhu, M., Phillipson, J. D., Greengrass, P. M., Bowery, N. E., Cai, Y. 1997. Plant Polyphenols: Biologically Active Compounds or Non-Selective Binders to Protein? Phytochemistry, 44(3): 441-447.
COMP-Inhibitor Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardiotonic
Choline-Sparing
Cytotoxic TC50=>100 ug/ml
Hypocholesterolemic
Hypoglycemic
Immunostimulant
Insulinogenic Economic & Medicinal Plant Research, 6: 170.
Lipoxygenase-1-Inhibitor IC50=60 mM
Lipoxygenase-Inhibitor IC50=140 uMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Lipoxygenase-Inhibitor IC97=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pancreatogenic
Pesticide
Reverse-Transcriptase-Inhibitor 10 ng/mlMcKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Vasodilator uMMcKenna, D. J., Hughes, K., and Jones, K. 2000. Green Tea Monograph. Alternative Therapies, 6(3): 61-82.
Xanthine-Oxidase-Inhibitor IC50=>40Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
16-ALPHA-HYDROXY-3-BETA-METHOXY-URSA-12,19(29)-DIEN-27,28-DIOIC-ACID Root Bark-- 8.0 *
27-O-BETA-D-GLUCOPYRANOSIDE-QUINOVIC-ACID Root Bark-- 9.0 *
3-BETA-6-BETA-19-ALPHA-TRIHYDROXY-23-OXO-URS-12-EN-28-OIC ACID Bark-- 57.4 *
3-BETA-6-BETA-19-ALPHA-TRIHYDROXY-URS-12-ENE-23-28-DIOIC ACID Root Bark-- 8.0 *
3-BETA-HYDROXY-3-OXO-URS-12-EN-27,28-DIOIC-ACID Root Bark-- -- *
3BETA,6BETA,19ALPHA-TRIHYDROXY-URS-12-EN-28-OIC-ACID Plant-- -- *
3BETA,6BETA,19ALPHA-TRIHYDROXY-URS-12-EN-28-OIC-ACID Root Bark197.0 250.0 *
3BETA,6BETA,19ALPHA-TRIHYDROXY-URS-12-EN-28-OIC-ACID Bark-- 65.0 *
5ALPHA-CARBOXYSTRICTOSIDINE Plant-- -- *
5ALPHA-CARBOXYSTRICTOSIDINE Root Bark-- 255.0 *
6-BETA-19-ALPHA-DIHYDROXY-3-OXO-URS-12-EN-28-OIC-ACID Root Bark-- 0.002 *
AKUAMMIGINE Root-- 300.0 *
Activities (3)
Adrenolytic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antimalarial
Sympatholytic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
AKUAMMIGINE Leaf-- 9200.0 *
Activities (3)
Adrenolytic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antimalarial
Sympatholytic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
ALLOISOPTEROPODINE Root-- -- *
Activities (1)
Immunostimulant
ALLOPTEROPODINE Root-- -- *
Activities (1)
Immunostimulant
ANGUSTINE Leaf-- -- *
Activities (1)
Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
BETA-SITOSTEROL Bark-- -- *
Activities (47)
Androgenic
Angiogenic
Anorexic Martindale's 28th
Antiadenomic Merck 11th Edition
Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
Anticancer (Lung)
Antiedemic IC54=320 mg/kg orl
Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antileukemic
Antilymphomic
Antimutagenic 250 ug/ml
Antiophidic 2.3 mg musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
Antiprostatadenomic Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
Antitumor (Lung)
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
Estrogenic
Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
Hypocholesterolemic 2-6 g/man/day/orlMartindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orlMartindale's 28th
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
Pesticide
Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
CAMPESTEROL Bark-- -- *
Activities (2)
Antioxidant IC37=10 uM
Hypocholesterolemic Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
CHLOROGENIC-ACID Bark-- -- Van Ginkel, A. 1996. Identification of the Alkaloids and Flavonoids from Uncaria tomentosa Bark by TLC in Quality Control. Phytotherapy Research, 10: S18-S19.
Activities (77)
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity)Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Allelochemic
Allergenic
Analgesic
AntiEBV Economic & Medicinal Plant Research, 6: 189.
AntiHIV Economic & Medicinal Plant Research, 6: 189.
AntiLegionella
Antiatherosclerotic
Antibacterial
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidiabetic
Antifeedant
Antigenotoxic
Antigonadotropic Jim Duke's personal files.
Antihemolytic 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatotoxic
Antiherpetic Economic & Medicinal Plant Research, 5: 194.
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukotriene
Antimelanogenic
Antimutagenic
Antinitrosaminic
Antioxidant IC53=200 ppmHuang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21.
Antioxidant IC80=12 uM
Antioxidant IC50=54.2 uM
Antiperoxidant IC50=36 uMPlanta Medica, 57: A54, 1991.
Antipolio Jim Duke's personal files.
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 9 x quercetin
Antiseptic
Antisunburn
Antithyroid Jim Duke's personal files.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC25=10 uM
Antiulcer Economic & Medicinal Plant Research, 6: 189.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Autotoxic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
CNS-Stimulant 1/6 Caffeine
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Clastogenic Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808.
Collagen-Sparing
Diuretic
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Histamine-Inhibitor
Hypoglycemic
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Interferonogenic Economic & Medicinal Plant Research, 1: 124.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC23=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
NO-Genic
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sunscreen
Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Vulnerary
CINCHONAIN-1-A Bark-- 25.0 *
CINCHONAIN-1-B Bark-- 65.0 *
CORYNOXEINE Root-- 510.0 *
Activities (1)
Calcium-Antagonist 10.1 uM rat
CORYNOXEINE Leaf-- 190.0 *
Activities (1)
Calcium-Antagonist 10.1 uM rat
DIHYDROCORYNANTHEINE Root-- 710.0 *
Activities (7)
(-)-Chronotropic
Adrenergic-Blocker
Antiarrhythmic
Antihypertensive
Antimalarial IC50=66 uMRukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial IC50=66 uMRukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Hypotensive
DIHYDROCORYNANTHEINE Leaf-- 800.0 *
Activities (7)
(-)-Chronotropic
Adrenergic-Blocker
Antiarrhythmic
Antihypertensive
Antimalarial IC50=66 uMRukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiplasmodial IC50=66 uMRukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Hypotensive
DIHYDROCORYNANTHEINE-N-OXIDE Leaf-- -- *
HIRSUTEINE Root-- 190.0 *
Activities (3)
Calcium-Antagonist
Neuroprotective
Vasodilator
HIRSUTEINE Leaf-- 140.0 *
Activities (3)
Calcium-Antagonist
Neuroprotective
Vasodilator
HIRSUTINE Leaf-- 330.0 *
Activities (8)
(-)-Chronotropic
Antiarrhythmic
Antihypertensive
Calcium-Antagonist 1 uM
Dopaminergic
Myocontractant
Neuroprotective
Vasodilator
HIRSUTINE Root-- 800.0 *
Activities (8)
(-)-Chronotropic
Antiarrhythmic
Antihypertensive
Calcium-Antagonist 1 uM
Dopaminergic
Myocontractant
Neuroprotective
Vasodilator
HIRSUTINE-N-OXIDE Leaf-- -- *
ISOAJMALICINE Leaf-- 310.0 *
ISOCORYNOXEINE Root-- 950.0 *
Activities (1)
Calcium-Antagonist 10.1 uM rat
ISOCORYNOXEINE Leaf-- 600.0 *
Activities (1)
Calcium-Antagonist 10.1 uM rat
ISOMITRAPHYLLINE Root Bark-- -- *
Activities (3)
Antileukemic IC50=45-60 uM/l
Immunostimulant
Phagocytotic
ISOMITRAPHYLLINE Root-- 3300.0 *
Activities (3)
Antileukemic IC50=45-60 uM/l
Immunostimulant
Phagocytotic
ISOMITRAPHYLLINE Stem Bark-- 20.0 *
Activities (3)
Antileukemic IC50=45-60 uM/l
Immunostimulant
Phagocytotic
ISOMITRAPHYLLINE Leaf-- 25000.0 *
Activities (3)
Antileukemic IC50=45-60 uM/l
Immunostimulant
Phagocytotic
ISOPTEROPODINE Leaf-- 3100.0 *
Activities (3)
Antileukemic IC54=25-35 uM/l
Immunostimulant 10-Jan
Phagocytotic 1-10 ug/l
ISOPTEROPODINE Root19.3 2800.0 *
Activities (3)
Antileukemic IC54=25-35 uM/l
Immunostimulant 10-Jan
Phagocytotic 1-10 ug/l
ISOPTEROPODINE Stem Bark60.0 630.0 *
Activities (3)
Antileukemic IC54=25-35 uM/l
Immunostimulant 10-Jan
Phagocytotic 1-10 ug/l
ISOPTEROPODINE Root Bark-- -- *
Activities (3)
Antileukemic IC54=25-35 uM/l
Immunostimulant 10-Jan
Phagocytotic 1-10 ug/l
ISORHYNCHOPHYLLINE Root45.5 21600.0 *
Activities (15)
Antiarrhythmic
Antidementia
Antiexcitotoxic
Antihypertensive
Antiischemic
Antioxidant
Antiradicular
CNS-Depressant
Calcium-Antagonist 10.1 uM rat
Hypotensive
Immunostimulant
Neuroprotective 100-1,000 uM
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Sedative
Vasodilator
ISORHYNCHOPHYLLINE Leaf-- 22200.0 *
Activities (15)
Antiarrhythmic
Antidementia
Antiexcitotoxic
Antihypertensive
Antiischemic
Antioxidant
Antiradicular
CNS-Depressant
Calcium-Antagonist 10.1 uM rat
Hypotensive
Immunostimulant
Neuroprotective 100-1,000 uM
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Sedative
Vasodilator
ISORHYNCHOPHYLLINE Root Bark-- -- *
Activities (15)
Antiarrhythmic
Antidementia
Antiexcitotoxic
Antihypertensive
Antiischemic
Antioxidant
Antiradicular
CNS-Depressant
Calcium-Antagonist 10.1 uM rat
Hypotensive
Immunostimulant
Neuroprotective 100-1,000 uM
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Sedative
Vasodilator
ISORHYNCHOPHYLLINE-N-OXIDE Leaf-- -- *
ISOROTUNDIFOLINE Stem-- -- *
MITRAPHYLLINE Root Bark-- -- *
Activities (12)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antihypertensive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antileukemic IC50=60-120 uM/l
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Myorelaxant
Pesticide
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Vasodilator
MITRAPHYLLINE Stem Bark30.0 500.0 *
Activities (12)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antihypertensive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antileukemic IC50=60-120 uM/l
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Myorelaxant
Pesticide
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Vasodilator
MITRAPHYLLINE Root-- 5000.0 *
Activities (12)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antihypertensive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antileukemic IC50=60-120 uM/l
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Myorelaxant
Pesticide
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Vasodilator
MITRAPHYLLINE Leaf-- 10900.0 *
Activities (12)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antihypertensive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antileukemic IC50=60-120 uM/l
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Myorelaxant
Pesticide
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Vasodilator
MITRAPHYLLINE Bark-- -- *
Activities (12)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antihypertensive Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antileukemic IC50=60-120 uM/l
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunostimulant
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Myorelaxant
Pesticide
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Vasodilator
OLEANOLIC-ACID Root Bark100.0 150.0 1.0 *
Activities (64)
Abortifacient
AntiHIV IC50=21.8 ug/ml
AntiHIV EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiPGE2 IC50=24 uM
AntiTGF-beta IC50=19-24 uM
Antiallergic
Antiarrhythmic 40 mg/kg
Antiatherosclerotic
Antibacterial MIC=625-1,250 ug/ml
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplement IC40-50 0.01 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiedemic IC36=40 mg/kg ipr rat
Antifertility
Antigingivitic MIC=625-1,250 ug/ml
Antihepatotoxic
Antihyperlipidemic
Antiinflammatory 40 mg/kg iprAquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.
Antiischemic 40 mg/kg
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene IC50=17 uM
Antimalarial IC50=70-89 ug/ml
Antinephritic IC50=19-24 uM
Antioxidant Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.
Antioxidant IC46=10 uM
Antiperiodontic MIC=625-1,250 ug/ml
Antiperoxidant IC30=200 ug/ml
Antiplaque MIC=625-1,250 ug/ml
Antiplasmodial IC50=70-89 ug/ml
Antisarcomic
Antiseptic MIC=625-1,250 ug/ml
Antitumor
Antitumor (Breast) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiulcer >carbenoxolone
Antiviral EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiviral IC50=21.8 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
COX-2-Inhibitor IC50=295 uM/
COX-2-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective 40 mg/kg
Cardiotonic
Cyclooxygenase-Inhibitor
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.
Hypolipemic
Hypotensive
Immunomodulator
Leucocytogenic
NF-kB-Inhibitor
Phagocytotic
Piscicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Prostaglandin-Synthesis-Inhibitor igs mus
Sedative
Uterotonic
Vasopressor
OLEANOLIC-ACID Plant-- -- *
Activities (64)
Abortifacient
AntiHIV IC50=21.8 ug/ml
AntiHIV EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiPGE2 IC50=24 uM
AntiTGF-beta IC50=19-24 uM
Antiallergic
Antiarrhythmic 40 mg/kg
Antiatherosclerotic
Antibacterial MIC=625-1,250 ug/ml
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplement IC40-50 0.01 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiedemic IC36=40 mg/kg ipr rat
Antifertility
Antigingivitic MIC=625-1,250 ug/ml
Antihepatotoxic
Antihyperlipidemic
Antiinflammatory 40 mg/kg iprAquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.
Antiischemic 40 mg/kg
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene IC50=17 uM
Antimalarial IC50=70-89 ug/ml
Antinephritic IC50=19-24 uM
Antioxidant Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.
Antioxidant IC46=10 uM
Antiperiodontic MIC=625-1,250 ug/ml
Antiperoxidant IC30=200 ug/ml
Antiplaque MIC=625-1,250 ug/ml
Antiplasmodial IC50=70-89 ug/ml
Antisarcomic
Antiseptic MIC=625-1,250 ug/ml
Antitumor
Antitumor (Breast) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiulcer >carbenoxolone
Antiviral EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiviral IC50=21.8 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
COX-2-Inhibitor IC50=295 uM/
COX-2-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective 40 mg/kg
Cardiotonic
Cyclooxygenase-Inhibitor
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.
Hypolipemic
Hypotensive
Immunomodulator
Leucocytogenic
NF-kB-Inhibitor
Phagocytotic
Piscicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Prostaglandin-Synthesis-Inhibitor igs mus
Sedative
Uterotonic
Vasopressor
PTEROPODINE Leaf-- 4800.0 *
Activities (3)
Antitumor
Cytotoxic
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
PTEROPODINE Stem Bark50.0 3000.0 *
Activities (3)
Antitumor
Cytotoxic
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
PTEROPODINE Root Bark-- -- *
Activities (3)
Antitumor
Cytotoxic
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
PTEROPODINE Root-- 5600.0 *
Activities (3)
Antitumor
Cytotoxic
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
PTEROPODINE Bark-- -- *
Activities (3)
Antitumor
Cytotoxic
Phagocytotic Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
QUINOVIC ACID-(28-1)-BETA-D-GLUCOSYL-BETA-D-GLUCOSYL ESTER Bark-- -- *
QUINOVIC ACID-3-BETA-O-(BETA-D-FUCOSYL)-(28-1)-BETA-D-GLUCOSYL ESTER Bark-- -- *
QUINOVIC ACID-3-BETA-O-(BETA-D-GLUCETA-D-GLUCOSYLESTEROSYL-(1-3)-BETA-D-FUCOSYL)-(28-1)-BETA-D-GLUCOSYL ESTER Bark-- -- *
QUINOVIC ACID-3-BETA-O-(BETA-D-GLUCOPYRANOSYL-(1-3)-BETA-D-FUCOPYRANOSIDE) Bark-- 46.0 *
QUINOVIC ACID-3-BETA-O-(BETA-D-GLUCOPYRANOSYL-(1-3)-BETA-D-FUCOPYRANOSY)-(28-1)-BETA-D-GLUCOPYRANOSYL ESTER Bark-- 50.0 *
QUINOVIC ACID-3-BETA-O-(BETA-D-GLUCOSYL-(1-3)-BETA-D-FUCOSIDE) Bark-- -- *
QUINOVIC ACID-3-BETA-O-(BETA-D-GLUCOSYL-(1-3)-BETA-D-FUCOSYL)-(27-1)-B Bark-- -- *
QUINOVIC ACID-3-BETA-O-(BETA-D-QUINOVOSYL)-(28-1)-BETA-D-GLUCOSYL ESTER Bark-- -- *
QUINOVIC ACID-3-BETA-O-BETA-D-FUCOSYL-27-BETA-D-GLUCOSYL ESTER Root Bark-- 160.0 *
QUINOVIC ACID-3-BETA-O-BETA-D-QUINOVOSYL-27-BETA-D-GLUCOSYL ESTER Root Bark-- 150.0 *
QUINOVIC-ACID-3-BETA-O-ALPHA-L-RHAMNOPYRANOSIDE Root Bark-- 17.0 *
QUINOVIC-ACID-3-BETA-O-ALPHA-L-RHAMNOPYRANOSYL-(1,3)-GLUCOPYRANOSYL Root Bark-- 18.0 *
QUINOVIC-ACID-3-BETA-O-BETA-D-QUINOVOPYRANOSYL-(1,3)-GALACTOPYRANOSYL Root Bark-- 7.0 *
QUINOVIC-ACID-3-BETA-O-BETA-D-QUINOVOPYRANOSYL-(1,3)-GLUCOPYRANOSYL Root Bark-- 7.0 *
QUINOVIC-ACID-3BETA-O-(BETA-D-GLUCOPYRANOSYL-(1->3)BETA-D-FUCOPYRANOSYL-(27->1)BETA-D-GLUCOPYRANOSYL-ESTER Bark-- 20.0 *
QUINOVIC-ACID-3BETA-O-BETA-D-FUCOPYRANOSIDE Bark-- -- *
QUINOVIC-ACID-3BETA-O-BETA-D-FUCOPYRANOSYL-(27->1)BETA-D-GLUCOPYRANOSYLESTER Bark-- -- *
QUINOVIC-ACID-3BETA-O-BETA-D-QUINOVOPYRANOSIDE Bark-- -- *
RHYNCHOPHYLLINE Root23.3 10300.0 *
Activities (23)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiaggregant
Antidementia
Antiexcitotoxic
Antihypertensive
Antiischemic
Antioxidant
Antipyretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiradicular
Antithrombotic
Calcium-Antagonist 10.1 uM rat
Calcium-Blocker
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Dopaminergic
Febrifuge
Hypotensive
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Neuroparalytic
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Sedative
Serotonergic
Uterotonic
Vasodilator
RHYNCHOPHYLLINE Leaf-- 7700.0 *
Activities (23)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiaggregant
Antidementia
Antiexcitotoxic
Antihypertensive
Antiischemic
Antioxidant
Antipyretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiradicular
Antithrombotic
Calcium-Antagonist 10.1 uM rat
Calcium-Blocker
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Dopaminergic
Febrifuge
Hypotensive
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Neuroparalytic
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Sedative
Serotonergic
Uterotonic
Vasodilator
RHYNCHOPHYLLINE Root Bark-- -- *
Activities (23)
Anesthetic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiaggregant
Antidementia
Antiexcitotoxic
Antihypertensive
Antiischemic
Antioxidant
Antipyretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiradicular
Antithrombotic
Calcium-Antagonist 10.1 uM rat
Calcium-Blocker
Cardiodepressant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Dopaminergic
Febrifuge
Hypotensive
Myocontractant Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Neuroparalytic
Protisticide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Sedative
Serotonergic
Uterotonic
Vasodilator
RHYNCHOPHYLLINE-N-OXIDE Leaf-- -- *
ROTUNDIFOLINE Stem-- -- *
RUTIN Bark-- -- Van Ginkel, A. 1996. Identification of the Alkaloids and Flavonoids from Uncaria tomentosa Bark by TLC in Quality Control. Phytotherapy Research, 10: S18-S19.
Activities (87)
5-HT-Inhibitor
Aldehyde-Oxidase-Inhibitor IC27-52=10 uM
Aldose-Reductase-Inhibitor 100 uM
Aldose-Reductase-Inhibitor 4 ug/mlIchikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelochemic
AntiCVI 270 mg/man/day
Antiaggregant ED50=33 nmol/kg iv
Antiallergic
Antiapoplectic
Antiatherogenic
Antiatherosclerotic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer
Anticapillary-Fragility 20-100 mg orl manMerck 7th Ed.
Anticataract
Anticlastogen
Anticonvulsant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antidementia Bruneton, J. 1999. Pharmacognosy, Phytochemistry, Medicinal Plants. 2nd Ed. Lavoisier Publishing, Paris. 1119 pp.
Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antidiabetic Jin, G-Z., Yamagata, Y., and Tomita, K.-i. 1989. Structure of Rutin Pentamethanol. Chem. Pharm. Bull. 38(2): 297-300, 1990.
Antiedemic 270 mg/day orl man
Antierythemic
Antifeedant
Antiglaucomic 60 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antihematuric
Antihemorrhoidal
Antihepatotoxic Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiherpetic Economic & Medicinal Plant Research, 5: 198.
Antihistaminic
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20 mg/kg
Antimalarial IC50=>100 ug/mlKhalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986.
Antimelanomic
Antimetastatic
Antimutagenic ID50=2-5 nM
Antinephritic
Antinociceptive
Antioxidant IC28=30 ppm
Antioxidant IC50=120 uM
Antioxidant IC54=10 uM
Antiperoxidant IC50=10-20 uM
Antiplatelet
Antiproliferant 50-75 uM/l
Antiprotozoal
Antipurpuric
Antiradicular 9 x quercetin
Antispasmodic
Antisunburn
Antithrombogenic EC50=500 nM
Antithyroid IC50=68 uM
Antitrypanosomic 100 mg/kgPlanta Medica, 57: A44, 1991.
Antitumor
Antitumor-Promoter
Antiulcer
Antivaricose
Antiviral
Apoptotic 75 uM/l
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Capillariprotective Merck 11th Edition
Catabolic
Chemopreventive
Cytoprotective IC50=3 uM
Estrogenic? Economic & Medicinal Plant Research, 6: 189.
Hemostat
Hepatomagenic 20,000 ppm (diet) ratPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective 20 mg/kg rat
Hypocholesterolemic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hypotensive Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Immunomodulator
Insecticide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat IC95=4,000-8,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC75=2.5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Mutagenic Economic & Medicinal Plant Research, 6: 189.
Myoprotective
Myorelaxant Economic & Medicinal Plant Research, 6: 189.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
PAF-Inhibitor
Pesticide
Protisticide
Radioprotective
Sunscreen
Topoisomerase-II-Inhibitor IC50=1 ug/mlBernard, F. X., Sable, S., Cameron, B., Provost, J., Desnottes, J. F., Crouzet, J., Blanche, F. 1997. Glycosylated Flavones as Selective Inhibitors of Topoisomerase IV. Antimicrobial Agents & Chemotherapy, 41: 992-998.
Vasodilator
Vasopressor
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
SPECIOPHYLLINE Stem Bark80.0 1600.0 *
Activities (1)
Antileukemic IC50=60 uM/l
SPECIOPHYLLINE Root-- 6600.0 *
Activities (1)
Antileukemic IC50=60 uM/l
SPECIOPHYLLINE Leaf-- 10800.0 *
Activities (1)
Antileukemic IC50=60 uM/l
SPECIOPHYLLINE Bark-- -- *
Activities (1)
Antileukemic IC50=60 uM/l
SPECIOPHYLLINE Root Bark-- -- *
Activities (1)
Antileukemic IC50=60 uM/l
STIGMASTEROL Bark-- -- *
Activities (12)
Antihepatotoxic
Antiinflammatory Lawrence Review of Natural Products, 1995
Antinociceptive
Antiophidic 2.3 mg ipr musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC33=10 uM
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Estrogenic
Hypocholesterolemic Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ovulant
Sedative
UNCARINE Bark-- -- *
UNCARINE-F Leaf-- 2800.0 *
Activities (1)
Antileukemic IC50=22-29 uM/l
UNCARINE-F Root-- 3100.0 *
Activities (1)
Antileukemic IC50=22-29 uM/l
UNCARINE-F Plant-- -- Fernando Cabieses, 1994.
Activities (1)
Antileukemic IC50=22-29 uM/l
UNCARINE-F Root Bark-- -- *
Activities (1)
Antileukemic IC50=22-29 uM/l
UNCARINE-F Stem Bark30.0 630.0 *
Activities (1)
Antileukemic IC50=22-29 uM/l
URSOLIC-ACID Plant-- -- *
Activities (89)
Analgesic
AntiEBV Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
AntiHIV EC50=2.0 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC85=18 ug/ml
AntiHIV 6.7 uM
AntiTGF-beta IC50=6-7.5 uM
Antialzheimeran Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Antiarrhythmic
Antiarthritic Planta Medica, 57: A56, 1991.
Antibacterial
Anticancer Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticancer (Colon) Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticholestatic 28-100 mg/kg orlShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Anticomplement IC100 0.1 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antidiabetic Chemical Constituents of Oriental Herbs (3 diff. books)
Antiedemic
Antiescherichic
Antifibrosarcomic IC80=10 uM
Antihepatotoxic 5-20 mg/kg iprShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antihistaminic Tsuruga, T., Chun, Y.-T., Ebizuka, Y., and Sankawa, U. 1991. Biologically Active Constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells. Chem. Pharm. Bull. 39(12): 3276-3278, 1991.
Antihyperlipidemic
Antiinflammatory 1/3 indomethacin
Antiinflammatory IC24=500 mg/kg
Antileishmanic ED50=20 uM
Antileukemic IC50=2.5-17.8 ug/ml
Antilymphomic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antimalarial IC50=28-37 ug/ml
Antimetastatic IC80=10 uM
Antimutagenic IC57-80=80 mg/kg
Antinephritic IC50=6-7.5 uM
Antiobesity? Internat. J. Oriental Med. 16: 4.
Antioxidant IC50=10 uM
Antiperoxidant IC35=200 ug/ml
Antiplasmodial IC50=28-37 ug/ml
Antiproliferative IC50=15-20 uM
Antistaphylococcic
Antithromboxane IC50=50 uM
Antitrypanosomic
Antitumor Cancer Research, 54: 701, 1994.
Antitumor (Breast) 0.5% diet
Antitumor (Breast) IC50=15-20 uM
Antitumor (Cervix) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Stomach) IC50=15-20 uM
Antitumor (brain) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor-Promoter Planta Medica, 57: A56, 1991.
Antiulcer Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antiviral IC85=18 ug/ml
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
CNS-Depressant
COX-2-Inhibitor IC50=130 uM/
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Cardioprotective
Cardiotonic
Choleretic 5-20 mg/kg orlShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Cyclooxygenase-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic 50 ppm
Cytotoxic ED50=3.75 ug/ml
Cytotoxic 7.2 uM
Diuretic
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective 1-100 ug/ml
Hepatoprotective 10 mg/kg
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive
Immunomodulator
Leucocytogenic
Lipoxygenase-Inhibitor IC50=0.18 mM
MMP-9-Inhibitor IC80=10 uM
Ornithine-Decarboxylase-Inhibitor
Pesticide
Piscicide
Potassium-Sparing 3 mg/ratIwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Protease-Inhibitor IC85=18 ug/ml
Protisticide Chemical Express, 7: 285, 1992.
Quinone-Reductase-Inducer 5 ug/mlLee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
Sodium-Sparing 3 mg/ratIwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
TOPO-2-Inhibitor
Trypanocide
Vasopressor
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.