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Activities: 229
All Chemicals: 26
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Chemical Low PPM High PPM StdDev *Reference
LIMONENE Plant-- -- *
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
PATULETIN Plant-- -- *
Activities (2)
Antispasmodic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Cholagogue
CIS-2-{4-(5-FORMYL-2-THIENYL)BUT-3-YN-1-ENYL}-FURAN Root-- -- *
CATECHIN Plant-- -- *
Activities (43)
Allelochemic IC86=1 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antiaggregant IC68=200 ug/ml
Antialcoholic 2,000 mg/man/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiarthritic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antibacterial MIC=>1,000 ug/mlPlanta Medica, 57: A42, 1991.
Anticariogenic
Antiedemic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiendotoxic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antiflu Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihepatitic 1 g 3x/day/manPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihepatotoxic Merck 11th Edition
Antiherpetic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihistaminic 1,000 mg 5x/day/manPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antihyperlipidemic Choi, J.S., Yokozawa,* T., and Oura, H. Antihyperlipidemic Effect Of Flavonoids From Prunus davidiana. Journal of Natural Products, 54(1): 218-224, 1991.
Antiinflammatory IC50=80 uM (cf indomethacin IC50=1 uM)
Antileukemic IC50=>10 ug/mlLife Sciences 55: 1061.
Antilipoperoxidant
Antiosteotic 500 mg 3x/dayPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antioxidant IC50=0.19 uM
Antioxidant 2.4 x Vit. E
Antiperiodontal Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiprostaglandin IC50=80 uM (cf indomethacin IC50=1 uM)
Antiradicular IC50=8 uMPlanta Medica, 56(6): 695, 1990.
Antisclerodermic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer 1 g/5x/day/man/orlPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiviral
Astringent Merck 11th Edition
COMP-Inhibitor Dullo, A. G., et al. 1999. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am. J. Clinical Nutrition, 70: 1040-1045.
COX-1-Inhibitor IC50=80 uM (cf indomethacin IC50=1 uM)
Cancer-Preventive
Carcinogenic
Cyclooxygenase-Inhibitor
Fungicide ED50=2.9-4.6 ug/mlLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Hemostat
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 253.
Hypocholesterolemic Choi, J.S., Yokozawa,* T., and Oura, H. Antihyperlipidemic Effect Of Flavonoids From Prunus davidiana. Journal of Natural Products, 54(1): 218-224, 1991.
Immunostimulant Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Lipoxygenase-Inhibitor IC96=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pesticide
Propecic
Xanthine-Oxidase-Inhibitor Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
P-CYMOL Plant-- -- *
CAFFEIC-ACID Plant-- -- *
Activities (102)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allergenic
Analgesic
AntiHIV EC50=200 ug/ml
AntiLegionella
Antiadenoviral Economic & Medicinal Plant Research, 5: 207.
Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaging
Antiatherogenic
Antibacterial
Anticancer
Anticarcinogenic Economic & Medicinal Plant Research, 6: 189.
Antidepressant
Antiedemic Economic & Medicinal Plant Research, 6: 189.
Antielastase IC50=93 um/l
Antielastase IC50=86 ug/ml (475 uM)
Antiescherichic
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antigonadotropic Jim Duke's personal files.
Antihemolytic 25 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatoadenomic 200 ppm diet orl mus
Antihepatotoxic
Antiherpetic 50 ug/ml
Antiherpetic EC50=>50 ug/ml
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene
Antimelanogenic
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antiophidic
Antioxidant 50 uM
Antioxidant IC57=30 ppm
Antioxidant 1/3 quercetin
Antioxidant 30 mM
Antioxidant 1.3 x Vit. E
Antioxidant 1/2 BHA
Antiperoxidant IC50=44 uMPlanta Medica, 57: A54, 1991.
Antiperoxidant IC35=200 ug/ml
Antiperoxidant IC85=100 ug/ml
Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiprostaglandin
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 1/3 quercetin
Antiradicular 30 mM
Antiradicular IC50=32-35 uM
Antiseptic
Antispasmodic EC50=3.4-15 uMPhytotherapy Research, 4: 73.
Antistaphylococcic
Antistomatitic Economic & Medicinal Plant Research, 5: 207.
Antisunburn
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithyroid Jim Duke's personal files.
Antitumor 200 ppm diet orl mus
Antitumor (Skin)
Antitumor-Promoter IC42=10 uMCancer Research, 48: 5941.
Antiulcerogenic
Antivaccinia Economic & Medicinal Plant Research, 5: 207.
Antiviral IC50=62.5 ug/ml
Anxiolytic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
COX-2-Inhibitor IC32=100 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 2% (diet)
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Co-carcinogenic
Collagen-Sparing
Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Cytotoxic TC50=200 ug/ml
DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Fungicide MIC=0.4 mg/ml
Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol)
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.
Hepatotropic
Histamine-Inhibitor
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC27=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=62-148 uM
Lyase-Inhibitor IC50=94-164 uM
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Prooxidant
Prostaglandigenic
Sedative 500 mg
Sunscreen IC50=2.5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC91=5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC98=25 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Tumorigenic Jim Duke's personal files.
Vulnerary
Xanthine-Oxidase-Inhibitor IC50=39.21 uMMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
VANILLIC-ACID Plant-- -- *
Activities (24)
Aldose-Reductase-Inhibitor 100 uM/l
Allelopathic
Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial 1.5-15 mg/mlRecio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticancer
Antifatigue
Antiinflammatory Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antioxidant IC21=30 ppm
Antioxidant 1/3 BHA
Antiperoxidant IC15-65=100-200 ug/ml
Antiradicular 7 x quercetin
Antiseptic
Antisickling Planta Medica, 56(6): 681, 1990.
Antitumor
Antitumor-Promoter
Ascaricide
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
Fungicide
Immunosuppressant
Laxative =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
Pesticide
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P-COUMARIC-ACID Plant-- -- *
Activities (25)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allelopathic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial Pharmazie, 46: 156, 1991.
Anticlastogen
Antifertility
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antinitrosaminic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antioxidant IC24=30 ppm
Antioxidant 1/3 BHA
Antiperoxidant IC50=>100 uMPlanta Medica, 57: A54, 1991.
Antiseptic
Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antitumor
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Lipoxygenase-Inhibitor IC11=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Pesticide
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor
Tyrosinase-Inhibitor ID50=3,650 uM
ALPHA-TERPINEOL Plant-- -- *
Activities (23)
ACE-Inhibitor 100 ug/ml (weak activity)
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacne
Antibacterial MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antiinflammatory
Antiproliferant
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cicatrizant ED50=240 ug/g mus
FLavor FEMA 5-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 1.29 uM/fly
Interleukin-6-Inhibitor
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide IC100=5 mg/g
Transdermal
Vulnerary ED50=240 ug/g mus
TRANS-2-{4-(5-FORMYL-2-THIENYL)BUT-3-YN-1-ENYL}-FURAN Root-- -- *
O-COUMARIC-ACID Plant-- -- *
Activities (4)
Allelopathic
Antibacterial Pharmazie, 46: 156, 1991.
Fungicide Pharmazie, 46: 156, 1991.
Pesticide
6-METHOXY-FLAVONES Plant-- -- *
THUJENE Plant-- -- *
NEPETIN Plant-- -- *
Activities (4)
Aldose-Reductase-Inhibitor ED50=1 uM
Anticataract
Antitumor
Xanthine-Oxidase-Inhibitor
TANNIN Root-- -- *
Activities (35)
Anthelmintic
AntiHIV
Antibacterial
Anticancer
Anticariogenic
Antidiarrheic
Antidysenteric
Antihepatotoxic
Antihypertensive
Antilipolytic
Antimutagenic
Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC50=1.44 ug/ml
Antioxidant 1/3 quercetin
Antiradicular 500 mg/kg/day orl musUchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antitumor
Antitumor-Promoter
Antiulcer
Antiviral
Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14.
Carcinogenic
Chelator
Cyclooxygenase-Inhibitor
Glucosyl-Transferase-Inhibitor
Hepatoprotective
Immunosuppressant
Lipoxygenase-Inhibitor
MAO-Inhibitor
Ornithine-Decarboxylase-Inhibitor
Pesticide
Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
MYRCENE Plant-- -- *
Activities (22)
ACE-Inhibitor 100 ug/ml
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allergenic
Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antibacterial
Anticonvulsant
Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antinitrosaminic
Antinociceptive 10-20 mg/kg ipr musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antinociceptive 20-40 mg/kg scu musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antioxidant Jim Duke's personal files.
Antispasmodic Jim Duke's personal files.
Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMA 0.5-9Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypothermic
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Myorelaxant 100-200 mg/kg
P450-2B1-Inhibitor IC50=0.14 uM
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
RESIN Plant-- -- *
MENTH-1-EN-4-OL Plant-- -- *
PINENE Plant-- -- *
Activities (12)
Allergenic
Antibacterial
Antiseptic
Antispasmodic Fitoterapia No.59-1984.
Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
Fungicide
Herbicide IC50=30 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Perfumery Merck 11th Edition
Pesticide
Spasmogenic Fitoterapia No.59-1984.
LUTEOLIN Plant-- -- *
Activities (78)
Aldose-Reductase-Inhibitor EC=3 ppmShin*, K.H., Chung, M.S., Chae, Y.J., Yoon, K.Y., Cho, T.S. 1992. A survey for aldose reductase inhibition of herbal medicines. Fitoterapia 64(2): 130, 1993.
Aldose-Reductase-Inhibitor IC50=0.45 uM rat
AntiHIV
Antiallergic
Antiangiogenic IC60-75=10 uM
Antiatherogenic
Antibacterial MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
Anticarcinogenic
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticataract EC=3 ppmShin*, K.H., Chung, M.S., Chae, Y.J., Yoon, K.Y., Cho, T.S. 1992. A survey for aldose reductase inhibition of herbal medicines. Fitoterapia 64(2): 130, 1993.
Anticomplementary
Antidermatic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antiherpetic 11-23 ug/ml
Antihistaminic <10-15 uM
Antiinflammatory #NAME?Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antileukemic 20-50 uM
Antilymphomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimelanomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimutagenic ID50=2-5 nM
Antimutagenic ID50=0.44 ug/ml
Antinociceptive
Antioxidant IC50=10 uM
Antipolio Economic & Medicinal Plant Research, 5: 197.
Antiproliferant
Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antitumor 1-50 uM
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Ovary) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Skin) 20 uM
Antitumor (Stomach) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Thyroid) 12-50 uM
Antitumor (brain) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitussive
Antiviral 11-23 ug/ml
Aphidifuge
Apoptotic 12-50 uM
Aromatase-Inhibitor IC35=1 uM/lJournal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic 1-50 uM
Deiodinase-Inhibitor Jim Duke's personal files.
Differentiator IC>40=40 uM
Diuretic Jim Duke's personal files.
Estrogenic 58% genistein
Hepatoprotective
Hyaluronidase-Inhibitor IC50+=100-250 uM
Hypocholesterolemic
ICAM-1-Inhibitor
IKK-Inhibitor
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lipoxygenase-Inhibitor
MAPK-Inhibitor
MMP-9-Inhibitor 20 uM
Metalloproteinase-Inhibitor
Myorelaxant
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor
PTK-Inhibitor 10-100 uM
Pesticide
Proliferant
Prostaglandin-Synthetase-Inhibitor
Protein-Kinase-C-Inhibitor IC70=50 uM
Succinoxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
TNF-alpha-Inhibitor IC50=14.44 uM
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
VEGF-Inhibitor IC50=2-7 uM
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=0.11 ug/mlChem. & Pharm. Bull. 38: 1772.
iNOS-Inhibitor
PHELLANDRENE Plant-- -- *
Activities (4)
Hyperthermic HerbalGram No. 22 - Spring 1990, page 45.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Spasmogenic Fitoterapia No.59-1984.
Tumor-Promoter
HISPIDULIN Plant-- -- *
Activities (7)
Antiaggregant IC50=13 ug/mlEconomic & Medicinal Plant Research, 5: 333.
Antihepatotoxic 32 mg/kg
Antioxidant ED=uM
Antiperoxidant
Antiradicular
Antitumor Lewis and Elvin-Lewis, Medical Botany, ca 1977
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
PHELLANDRAL Plant-- -- *
EO Flower-- 8600.0 -0.14 *
PECTOLINARIGENIN Plant-- -- *
Activities (2)
Aldose-Reductase-Inhibitor IC25=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
CRYPTONE Plant-- -- *
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.