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Activities: 252
All Chemicals: 61
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Chemical Low PPM High PPM StdDev *Reference
EO Plant15000.0 58000.0 3.67 *
ALPHA-GUAIENE Plant1261.0 5460.0 1.0 *
TANNIN Plant-- 17000.0 -0.97 *
Activities (35)
Anthelmintic
AntiHIV
Antibacterial
Anticancer
Anticariogenic
Antidiarrheic
Antidysenteric
Antihepatotoxic
Antihypertensive
Antilipolytic
Antimutagenic
Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC50=1.44 ug/ml
Antioxidant 1/3 quercetin
Antiradicular 500 mg/kg/day orl musUchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antitumor
Antitumor-Promoter
Antiulcer
Antiviral
Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14.
Carcinogenic
Chelator
Cyclooxygenase-Inhibitor
Glucosyl-Transferase-Inhibitor
Hepatoprotective
Immunosuppressant
Lipoxygenase-Inhibitor
MAO-Inhibitor
Ornithine-Decarboxylase-Inhibitor
Pesticide
Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
GUAIACOL Leaf-- -- *
Activities (18)
Anesthetic
Antibacterial 8,000 ppmValnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antidermatitic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antieczemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiesophagitic Martindale's 29th
Antiseptic Martindale's 29th
Antituberculic
Cardiodepressant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Cardiotonic
Dermal Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Emetic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Expectorant 0.3-0.6 ml/manMartindale's 28th
FLavor FEMA <1-1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Pesticide
Prostaglandin-Synthesis-Inhibitor IC50=57 uMAlanko, J., et al. 1999. Modulation of Arachidonic Acid Metabolism by Phenols: Relation to their Structure and Antioxidant/Proooxidant Properties. Free Radical Biol Med, 26(1/2): 193-201.
Transdermal Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
2-METHYL-BUTYRIC-ACID Leaf-- -- *
CINNAMALDEHYDE Plant-- -- *
Activities (60)
Acaricide
Adrenergic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Allelochemic IC100=2.5 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic
Anesthetic Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Antiaggregant 200 uMEconomic & Medicinal Plant Research, 5: 343.
Antibacterial MIC=250-1,000 ug/ml
Antienterococcic MIC=250 ug/ml
Antiescherichic MIC=500 ug/ml
Antiherpetic
Antiinflammatory Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Antiklebsiellic MIC=1,000 ug/ml
Antileukemic
Antimutagenic HerbalGram No. 24, page 40.
Antipneumonic MIC=1,000 ug/ml
Antipseudomonic MIC=1,000 ug/ml
Antipyretic
Antisalmonella MIC=500 ug/ml
Antispasmodic
Antistaphylococcic MIC=250 ug/ml
Antiulcer 500 mg/kg/orl
Antiurease
Antiviral
CNS-Depressant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
CNS-Stimulant Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
COX-2-Inhibitor IC50=245 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide MIC=16-40 ppm
Choleretic 500 mg/kg/orl
Chronotropic
Circulatory-Stimulant
Cyclooxygenase-Inhibitor Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Cytotoxic ED50=5-60 ug/ml
FLavor
Fungicide 1.7-250 ppm
Fungicide MIC=16-40 ppm
Herbicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Histaminic
Hypoglycemic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Hypotensive Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Hypothermic
Inotropic
Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Lipoxygenase-Inhibitor Hutchings, A, Scott, AH, Lewis, G, and Cunningham, A. 1996. Zulu Medicinal Plants. An inventory. University of Natal Press, Pietermaritzburg. 450 pp.
Monoaminergic
Mutagenic
Nematicide 100 ug/mlShoyakugaku Zasshi, 44: 183.
Perfumery
Pesticide
Sedative
Sprout-Inhibitor Duke, J.A.. Personal Communication.
Teratogenic
Termiticide LD96=1 mg/g
Termiticide LD100=5 mg/g
Tranquilizer
Tyrosinase-Inhibitor ID50=129 ug/ml
Tyrosinase-Inhibitor ID50=970 uM
Vasodilator
Vibriocide MIC=250 ug/ml
TRANS-2-PENTYLCYCLOPROPYLCARBOXYLIC-ACID Leaf-- -- *
P-VINYL-PHENOL Leaf-- -- *
APIGENIN Plant-- -- *
Activities (101)
11B-HSD-Inhibitor
AntiADD
AntiHIV IC72=200 ug/ml
AntiHIV IC50=143 ug/ml
Antiaflatoxin IC50=9.52 uM
Antiaflatoxin IC50=2.57 ppm
Antiaggregant
Antiaging
Antiallergic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiangiogenic 4 uM
Antiarrhythmic
Antibacterial Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticancer (Lung)
Anticomplementary
Antidermatitic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiherpetic 20-54 ug/ml
Antihistaminic IC50=10-35 uM
Antiinflammatory #NAME?
Antiinflammatory IC~65=1,000 uM
Antileukemic 20-50 uM
Antimelanomic 1-50 uM
Antimetastatic 1-50 uM
Antimutagenic ID50=10-40 nMPhenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimutagenic ID50=0.55 ug/ml
Antioxidant 1.5 x Vit. E
Antioxidant IC28.5=62.5 ug/ml
Antiperistaltic
Antiproliferant 1-50 uM
Antiproliferant IC50=155 uM
Antispasmodic EC50=1-5 uM
Antistress 10 mg/kg
Antithyroid Jim Duke's personal files.
Antitumor 1-50 uM
Antitumor (Breast) 1-50 uM
Antitumor (Lung)
Antitumor (Skin)
Antiviral 20-54 ug/ml
Anxiolytic 10 mg/kg
Apoptotic 12-60 uM
Aromatase-Inhibitor IC65=1 uM/lJournal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
CNS-Depressant
COX-1-Inhibitor IC65=1,000 uM
COX-2-Inhibitor IC>65=1,000 uM
COX-2-Inhibitor <40 uM
COX-2-Inhibitor IC50=<15 uM
Calcium-Antagonist? Biochimica & Biophysica Acta, 1115: 69, 1991.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
Cyclooxygenase-Inhibitor
Cytochrome-P450-1A1-Inhibitor
Cytotoxic IC88=10 ug/mlPlanta Medica, 57: A113, 1991.
Cytotoxic 1-50 uM
Cytotoxic IC50=9.5 uM
DNA-Protective
Deiodinase-Inhibitor Jim Duke's personal files.
Differentiator MIC=30 uM
Differentiator IC40=40 uM
Diuretic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Estrogenic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
Estrogenic 16% genistein
Estrogenic EC50=1 uM
HIF-1alpha-Inhibitor
Hyaluronidase-Inhibitor IC50+=50-250 uM
Hypotensive Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ICAM-1-Inhibitor
IKK-Inhibitor
Inotropic
Interleukin-6-Inhibitor
MAO-Inhibitor
MAPK-Inhibitor
Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Mutagenic
Myorelaxant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
NADH-Oxidase-Inhibitor
NF-kB-Inhibitor
NO-Synthase-Inhibitor 5-50 uM
Nodulation-Signal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ornithine-Decarboxylase-Inhibitor
P21-Inducer 10-70 uM
PKC-Inhibitor IC50=10 uM
PTK-Inhibitor 10-100 uM
Pesticide
Polyamine-Synthesis-Inhibitor
Progestational
Protein-Kinase-C-Inhibitor IC50=10-40 uM
Quinone-Reductase-Inducer 20 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Radioprotective
Sedative 30-100 mg/kg
Sunscreen
TNF-alpha-Inhibitor IC50=3.27 uM
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
Topoisomerase-II-Inhibitor 50 ug/mlAzuma, Y., Onishi, Y., Sato, Y., Kizaki, H. 1995. Effects of Protein Tyrosine Kinase Inhibitors With Different Modes of Action on Topoisomerase Activity and Death of IL-2-Dependent CTLL-2-Cells. J Biochemistry, 118: 312-318.
Topoisomerase-II-Inhibitor IC28=18 uM
Topoisomerase-II-Inhibitor IC45=180 uM
Uterotrophic EC50=0.1-25 uM/lJournal of Medicinal Food 2: 227.1999.
VEGF-Inhibitor IC50=2-7 uM
Vasodilator
Xanthine-Oxidase-Inhibitor 0.36 uM
iNOS-Inhibitor IC50=<15 uM
GAMMA-PATCHOULENE Plant-- -- *
1-BETA,5-BETA-EPOXY-ALPHA-GUAIENE Plant-- -- *
CARYOPHYLLENE-OXIDE Plant-- -- *
Activities (8)
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Calcium-Antagonist ED50=32 uM gpg
Fungicide
Insecticide Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Pesticide
OMBUINE Plant-- -- *
ALPHA-PINENE Plant-- -- *
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
EUGENOL Plant-- -- *
Activities (76)
Acaricide LD50=5.47 ug/sq cm cf DEET at 37.59 ug/sq cm
Allergenic
Analgesic Merck 11th Edition
Anesthetic 200-400Phytotherapy Research, 4: 93.
AntiTNF
Antiaggregant IC50=0.3 uMPhytotherapy Research, 4: 93.
Antiarachidonate
Antibacterial 500 ppmValnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antibacterial MBC=400 ug/ml
Anticonvulsant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic 100Phytotherapy Research, 4: 95.
Antiestrogenic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antigenotoxic 50-500 mg/kg orl mus
Antiherpetic IC50=16.2-25.6 ug/ml
Antiinflammatory (11 uM) IC~97=1,000 uM
Antikeratotic IC50=16.2-25.6 ug/ml
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antinitrosating
Antioxidant IC65=30 ppm
Antioxidant 10 uM
Antiprostaglandin 11 uM
Antiprostaglandin IC50=9.2 mM
Antipyretic 3 ml/man/day
Antiradicular EC50=2 ul/l
Antisalmonella MIC=400 ug/ml
Antiseptic 3 ml/man/day
Antiseptic 400 ug/ml
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antithromboxane Lawrence Review of Natural Products, Jul-87.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer
Antiviral IC50=16.2-25.6 ug/ml
Apifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
COX-1-Inhibitor IC97=1,000 uM
COX-2-Inhibitor IC>97=1,000 uM
COX-2-Inhibitor IC50=129 uM
Calcium-Antagonist IC50=224 uM
Calcium-Antagonist IC50=200 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Phytotherapy Research, 4: 93.
Carcinogenic? Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Choleretic
Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima.
Cytotoxic 25 ug/mlPhytotherapy Research, 4: 93.
Dermatitigenic
Enterorelaxant J. Aromatherapy 4: 22.
FLavor FEMA 10-500Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective 100 ppm
Herbicide
Insecticide
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvicide
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=2,000 ug/mlShoyakugaku Zasshi, 44: 183.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Prostaglandin-Synthesis-Inhibitor 1 mM rbtChen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Prostaglandin-Synthesis-Inhibitor IC50=9.2 uM
Sedative
Termiticide LD100=5 mg/g
Trichomonicide LD100=300 ug/ml
Trichomonistat IC50=10 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer Lawrence Review of Natural Products, Dec-93.
Ulcerogenic Phytotherapy Research, 4: 93.
Varroacide
Vasodilator
Vermifuge
1-ALPHA,5-ALPHA-EPOXY-ALPHA-GUAIENE Plant-- -- *
CADINENE Plant-- -- *
Activities (4)
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
FLavor FEMA 400-4,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
SEYCHELLENE Plant-- -- *
OCTANOIC-ACID Leaf-- -- *
Activities (5)
Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 3-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
ALPHA-PATCHOULENE Plant-- -- *
EPOXYCARYOPHYLLENE Plant-- -- *
1,10-EPOXY-ALPHABULNESENE Plant-- -- *
BULNESOL Plant-- -- *
RHAMNETIN Plant-- -- *
Activities (18)
Aldose-Reductase-Inhibitor IC57=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
Aldose-Reductase-Inhibitor IC23=1 uM
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaflatoxin IC50=1.29 uM
Antiaflatoxin 0.41 ppm
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antioxidant
Antiradicular 7 x quercetin
Antitumor
Antitumor-Promoter
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Dye Merck 11th Edition
Hepatoprotective IC50=1.29 uM
Mutagenic
Pesticide
Quinone-Reductase-Inducer Yannai, S., Day, A. J., Williamson, G., Rhodes, M. J. C. 1998. Characterization of Flavonoids as Monofunctional or Bifunctional Inducers of Quinone Reductase in Murine Hepatoma Cell Lines. Food Chem Toxicol, 36(8): 623-630.
O-CRESOL Leaf-- -- *
Activities (6)
Allelochemic IC50=0.36 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiseptic Merck 11th Edition
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Pesticide
Rodenticide LD 50=620 cut rat
ALPHA-GUAIENE-OXIDE Plant-- -- *
EPIGUAIPYRIDINE Plant-- -- *
POGOSTONE Plant-- -- *
Activities (4)
Antibacterial MIC=39-625Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134.
Antiplaque MIC=39-625 ug/mlOsawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21
Fungicide Osawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21
Pesticide
BETA-PINENE Plant-- -- *
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
NORPATCHOULENOL Plant-- -- *
POGOSTOL Plant-- -- *
BETA-PATCHOULENE Plant120.0 464.0 *
NORDEHYDROPATCHOULOL Plant-- -- *
ALPHA-BULNESONE Plant1260.0 5460.0 *
DIMETHYLPHENOL Leaf-- -- *
PHENOL Leaf-- -- *
Activities (26)
Analgesic Martindale's 29th
Anesthetic
AntiMS Martindale's 29th
Antibacterial
Antihemorrhoidal Martindale's 28th
Antihydrocoele Martindale's 29th
Antiincontinence Martindale's 29th
Antionychogryphotic Martindale's 28th
Antiotitic Martindale's 28th
Antioxidant Jim Duke's personal files.
Antiprostatitic Martindale's 29th
Antipyruvetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiseptic
Antisinusitic Martindale's 28th
Antispastic Martindale's 28th
Antiviral Martindale's 29th
Antiwrinkle Martindale's 28th
CNS-Depressant Martindale's 29th
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic
Emetic Martindale's 29th
Fungicide Martindale's 29th
Hemolytic 5,400 ppmMartindale's 28th
Pesticide
Rodenticide LD50=1,040 cut rat
Vasodilator
BETA-ELEMENE Plant-- -- *
Activities (5)
Anticancer (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antigliomic
Antiproliferant
Antitumor (Cervix) Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Apoptotic
NONANOIC-ACID Leaf-- -- *
Activities (2)
FLavor FEMA 1-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
ALPHA-BULNESENE-OXIDE Plant-- -- *
DHELWANGIN Plant-- 2500.0 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
DHELWANGIN Hh-- 2500.0 *
PENTANOIC-ACID Leaf-- -- *
BENZALDEHYDE Plant-- -- *
Activities (24)
Allergenic
Anesthetic
Antibacterial
Anticancer
Antimutagenic
Antipeptic
Antiseptic
Antispasmodic
Antitumor
Candidicide
FLavor FEMA 150-800Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Immunostimulant
Insecticide Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Insectifuge 50 ppmJ. Stored. Prod. Res., 22:141, 1986.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Narcotic Merck 11th Edition
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide LD100=5 mg/g
Tyrosinase-Inhibitor ID50=820 uM
Tyrosinase-Inhibitor ID50=87 ug/ml
Tyrosinase-Inhibitor ID50=0.82 mM
Tyrosinase-Inhibitor ID50=830 uM
HUMULENE Plant-- -- *
Activities (2)
Antimalarial IC50=86 ug/ml
Antiplasmodial IC50=86 ug/ml
ALPHA-BULNESENE Plant-- -- *
LIMONENE Plant-- -- *
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
DEHYDRACETIC-ACID Leaf-- -- *
PATCHOULIPYRIDINE Plant-- -- *
AZULENE Plant-- -- *
Activities (10)
Antiallergic Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antibacterial 500 ppmValnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antihistaminic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiinflammatory Pakistan Encyclopedia Planta Medica. 1986.
Antipyretic HerbalGram No. 20, page 40.
Antiseptic 6-500Valnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antispasmodic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiulcer ED50=150 (orl)
Hepatoregenerative Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
HEPTANOIC-ACID Leaf-- -- *
4-METHYL-PENTANOIC-ACID Leaf-- -- *
CARYOPHYLLENE Plant-- -- *
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CYCLOSEYCHELLENE Plant-- -- *
PATCHOULI-ALCOHOL Plant2100.0 23200.0 *
Activities (4)
Antibacterial MIC=39->2,500Russell, G. B., Phytochemical resources for crop protection, N. Z. J. Technol., 2, 1986, 127-134.
Antiplaque MIC=39-2,500 ug/mlOsawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21
Fungicide Osawa, K., Matsumoto, T., Maruyama, T., Takiguchi, T., Okuda, K., and Takazoe, I., Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria, Bull Tokyo Dent. Coll., 31 (1), 1990, 17-21
Pesticide
APIGENIN-7-O-BETA-GLUCOSIDE Plant-- -- *
GUAIPYRIDINE Plant-- -- *
2-METHYLHEXANOIC-ACID Leaf-- -- *
CIS-2-PENTYLCYCLOPROPYLCARBOXYLIC-ACID Leaf-- -- *
CAMPHENE Plant-- -- *
Activities (9)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Jim Duke's personal files.
Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
FLavor FEMA 15-175Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Spasmogenic Fitoterapia No.59-1984.
PACHYPODOL Plant-- -- *
Activities (2)
Antiviral Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
APIGENIN-7-O-BETA-D-(-6'-P-COUMAROYL)-GLUCOSIDE Plant-- -- *
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.