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Activities: 175
All Chemicals: 28
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Chemical Low PPM High PPM StdDev *Reference
TERPINOLENE Leaf-- 1.0 -0.23 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (9)
Allelochemic
Antifeedant
Antinitrosaminic
Antioxidant
Deodorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 15-60Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
TERPINEN-4-OL Leaf-- 2460.0 1.06 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (23)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacetylcholinesterase IC21-24=1.2 mM
Antiacne
Antiallergic
Antiasthmatic Chin. J. Tuber. Respir. Dis., 4:203, 1982.
Antibacterial
Antioxidant
Antiseptic Flav. & Frag. J. 9: 129.
Antispasmodic
Antitussive Chin. J. Tuber. Respir. Dis.
Antiulcer
Bacteriostatic Chin. J. Tuber. Respir. Dis.
Diuretic 0.1 ml/rat
Fungicide
Herbicide IC50=200 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=22 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge
Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Renoirritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Spermicide ED100=0.015
Vulnerary Lawrence Review of Natural Products, Jan-91.
PULEGONE Leaf13710.0 18780.0 1.74 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (28)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiacetylcholinesterase IC50=0.9 mM
Antiacetylcholinesterase IC50=136 ug/ml
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antibacterial Economou, D., and Nahrstedt, A. 1991. Chemical, Physiological, and Toxicological Aspects of the Essential Oil of Some Species of the Genus Bystropogon*. Planta Medica, 57: 347, 1991.
Anticholinesterase Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antihistaminic Ortiz De Urbina, A.V., Martin, M.L., Montero, M.J., Carron, R., Sevilla, M.A., San Roman, L. 1989. Antihistaminic activity of pulegone on the guinea-pig ileum. J. Pharm. Pharmacol. 42: 295-296, 1990.
Antipyretic
Avifuge
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Economou, D., and Nahrstedt, A. 1991. Chemical, Physiological, and Toxicological Aspects of the Essential Oil of Some Species of the Genus Bystropogon*. Planta Medica, 57: 347, 1991.
Cerebrotoxic orl manJ. Aromatherapy 4: 24.
Encephalopathic 80 mg/kg orl ratLawrence Review of Natural Products, Jan-92.
FLavor FEMA 5-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Economou, D., and Nahrstedt, A. 1991. Chemical, Physiological, and Toxicological Aspects of the Essential Oil of Some Species of the Genus Bystropogon*. Planta Medica, 57: 347, 1991.
Glutathionalytic Lawrence Review of Natural Products, Jan-92.
Hallucinogenic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Hepatotoxic Lewis, E.J. and Friedrich, E.C. 1989. The Essential Oil of Poliomintha incana. Planta Medica 56(2): 224-226, 1990.
Herbicide IC50=1.5 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Insectifuge
Nephrotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Neurotoxic
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Pulifuge
Pulmonotoxic
Sedative
PIPERITONE Leaf840.0 7710.0 3.7 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (7)
Antiasthmatic
FLavor FEMA 1-2Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=75 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge (> DEET)Bowers, W.S., Ortego, F., You, X., and Evans, P.H. Insect Repellents From The Chinese Prickly Ash Zanthoxylum bungeanum. Journal of Natural Products, 56(6): 935-938, 1993.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
PIPERITENONE-OXIDE Leaf-- 1880.0 -0.84 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (2)
Insecticide Shah, G.C., Bhandari, R. & Mathela, C.S. 1992. 1,2-Epoxy-p-Menthane Derivatives from some Labiatae Species. J. Ess. Oil Res. 4: 57-59.
Pesticide
PIPERITENONE Leaf-- 2380.0 1.23 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (3)
Antiacetylcholinesterase IC50=110 ug/ml
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Toxic 10,000/manAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
P-CYMENE Leaf-- 150.0 -0.28 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (16)
Analgesic Martindale's 28th
Antiacetylcholinesterase IC40=1.2 mM
Antibacillary
Antibacterial
Antiflu
Antirheumatalgic Martindale's 28th
Antiviral
FLavor FEMA 12-250Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Herbicide IC50=50 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Laxative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide LD100=50 ug/ml
MYRCENE Leaf-- 300.0 -0.06 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (22)
ACE-Inhibitor 100 ug/ml
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allergenic
Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antibacterial
Anticonvulsant
Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antinitrosaminic
Antinociceptive 10-20 mg/kg ipr musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antinociceptive 20-40 mg/kg scu musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antioxidant Jim Duke's personal files.
Antispasmodic Jim Duke's personal files.
Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMA 0.5-9Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypothermic
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Myorelaxant 100-200 mg/kg
P450-2B1-Inhibitor IC50=0.14 uM
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
MENTHONE Leaf1.0 6000.0 0.12 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (30)
Acaricide
Allelopathic
Analgesic
Antiacetylcholinesterase IC50=1.4 mM
Antiaggregant IC50=750
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacillary MIC=1.25 mg/ml
Antibacterial MIC=0.625-5 mg/ml
Antiescherichic MIC=5 mg/ml
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Antilisteria MIC=1.25 mg/ml
Antisalmonella MIC=5 mg/ml
Antiseptic 2.25 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antispasmodic ED50=0.044 mg/mlFitoterapia No.59-1984.
Antistaphylococcic MIC=0.625-2.5 mg/ml
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide MIC=2.5 mg/ml
Cerebrotoxic orl manJ. Aromatherapy 4: 24.
Culicide LC50=156-194 mg/l
FLavor FEMA 5-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insecticide LC50=156-194 mg/l
Larvicide LC50=156-194 mg/l
Mutagenic
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Psychoactive
Sedative Ortiz de Urbina, A.V., Martin*, M.L., Montero, M.J., Moran, A., and San Roman, L. 1988. Sedating and Antipyretic Activity of the Essential Oil of Calamintha sylvatica subsp. Ascendens. Journal of Ethnopharmacology, 25: 165-171, 1989.
Trichomonicide LD100=600 ug/ml
MENTHOL Leaf-- 3030.0 -0.26 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (63)
Allergenic Martindale's 29th
Analgesic Martindale's 28th
Anesthetic 2,000 ppmYamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Antiacetylcholinesterase IC50=2.0 mM
Antiaggregant IC50=750
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antiasthmatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antibacillus MIC=1.25 mg/ml
Antibacterial MIC=0.625-2.5
Antibronchitic Martindale's 28th
Antidandruff A.L.L. Hunting. Encyclopedia of Shampoo Ingredients. Micelle Press, Cranford NJ. 467 pp.
Antiescherichic MIC=1.25 mg/ml
Antihalitosic American Health, 12(4): 17, 1993.
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Antiinflammatory Martindale's 28th
Antilisteria MIC=0.625 mg/ml
Antineuralgic
Antiodontalgic Martindale's 28th
Antipruritic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Antipyretic
Antirheumatic Martindale's 28th
Antisalmonella MIC=0.625 mg/ml
Antiseptic 4 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antisinusitic Martindale's 28th
Antispasmodic ED50=0.01 mg/mlFitoterapia No.59-1984.
Antistaphylococcic MIC=0.625 mg/ml
Antistreptococcic MIC=0.4 mg/ml
Antitartar
Antivaginitic
Antivulvitic
Bradycardic 65 mg/3 x day/womanMartindale's 28th
Bronchomucolytic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
Bronchomucotropic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Bronchorrheic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
CNS-Depressant
CNS-Stimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calcium-Antagonist
Candidicide MIC=0.625 mg/ml
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Choleretic
Ciliotoxic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Congestant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Counterirritant
Decongestant? 11 mg/manEccles, R., et al. 1989. The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. J. Pharm. Pharmacol. 42: 652-654, 1990.
Dermatitigenic
Diaphoretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Enterorelaxant J. Aromatherapy 4: 22.
Expectorant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Gastrosedative Merck 11th Edition
Irritant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Myorelaxant Martindale's 29th
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Neurodepressant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Neuropathogenic 40-100 mg/day/ratYamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Nociceptive Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Perfumery Merck 11th Edition
Pesticide
Refrigerant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Rubefacient
Termiticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Transdermal
Vibriocide
LIMONENE Leaf-- 1.0 -0.45 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
ISOPULEGOL Leaf-- 180.0 -0.34 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (3)
Antiacetylcholinesterase IC50=2.0 mM
FLavor FEMA 5-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
ISOMENTHONE Leaf1110.0 7080.0 1.64 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (3)
Antiacetylcholinesterase IC50=1.6 mM
Antioxidant
Antiradicular
GAMMA-TERPINENE Leaf-- 1.0 -0.37 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (11)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC23=1.2 mM
Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Antioxidant Jim Duke's personal files.
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
EO Leaf-- 30000.0 1.62 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
DELTA-CADINENE Leaf-- 1.0 -0.46 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (9)
Aldose-Reductase-Inhibitor
Antiacne
Antibacterial MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antistreptococcic
Cytochrome-P450-Inducer
P450-Inducer
Pesticide
Testosterone-Inducer
CIS-BETA-OCIMENE Leaf-- 120.0 -0.71 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
CARVONE Leaf-- 90.0 -0.26 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (19)
Allergenic
Antiacetylcholinesterase IC50=1.4-1.8 mM
Antiproliferative
Antiseptic 1.5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
FLavor FEMA 80-3,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Trichomonicide LD100=300 ug/ml
Vermicide
CAMPHENE Leaf1.0 1.0 -0.19 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (9)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Jim Duke's personal files.
Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
FLavor FEMA 15-175Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Spasmogenic Fitoterapia No.59-1984.
BORNEOL Leaf-- 570.0 0.23 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (35)
(-)-Chronotropic 29 ug/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 29 ug/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Allelochemic
Analgesic
Antiacetylcholine Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial MIC=125-250 ug/ml
Antibronchitic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiescherichic MIC=125 ug/ml
Antifeedant
Antiinflammatory
Antiotitic
Antipyretic
Antisalmonella MIC=125 ug/ml
Antispasmodic ED50=0.008 mg/ml
Antistaphylococcic MIC=250 ug/ml
Antiyeast MIC=250 ug/ml
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
CNS-Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Candidicide MIC=250 ug/ml
Choleretic
FLavor FEMA<1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective
Herbicide IC50=470 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=470 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Inhalant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insect-Repellent
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Medline (post 1990 searches filed in my computer)
Tranquilizer
BICYCLOELEMENE Leaf-- 1.0 -1.05 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
BETA-PINENE Leaf-- 960.0 0.99 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
BETA-CARYOPHYLLENE Leaf-- 2640.0 0.96 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
ALPHA-TERPINEOL Leaf-- 1.0 -0.59 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (23)
ACE-Inhibitor 100 ug/ml (weak activity)
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacne
Antibacterial MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antiinflammatory
Antiproliferant
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cicatrizant ED50=240 ug/g mus
FLavor FEMA 5-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 1.29 uM/fly
Interleukin-6-Inhibitor
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide IC100=5 mg/g
Transdermal
Vulnerary ED50=240 ug/g mus
ALPHA-PINENE Leaf1.0 390.0 -0.2 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
ALPHA-GUAIENE Leaf-- 1.0 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
3-OCTANOL Leaf-- 1.0 -0.51 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
Activities (2)
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
1-OCTEN-3-OL Leaf-- 120.0 0.46 Kirimer, N., Ozek, T., and Baser, K.H.C. 1991. Composition of the Essential Oil of Micromeria congesta. J. Ess. Oil Res., 3: 387-393.
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.