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Activities: 448
All Chemicals: 127
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Chemical Low PPM High PPM StdDev *Reference
(+)-1,2-EPOXYNEOMENTHYL-ACETATE Leaf-- 5000.0 *
(+)-8-ACETOXY-CARVONE Essential Oil-- -- Jim Duke's personal files.
(+)-CARVONE Essential Oil-- -- Jim Duke's personal files.
Activities (2)
Antialzheimeran? L. Gracza (1985) as cited by Buchbauer re antiacetylcholinesterase.
Anticholinesterase L. Gracza (1985) as cited by Buchbauer re antiacetylcholinesterase.
(+)-ISOMENTHONE Leaf240.0 7062.0 1.26 *
(+)-MENTHOFURAN Leaf-- 32.0 -0.76 *
(+)-MENTHYL-ACETATE Leaf300.0 1900.0 *
(+)-NEOMENTHOL Leaf1100.0 2200.0 0.92 *
(+)-OCTAN-3-ONE Leaf9000.0 27000.0 *
(+)-PIPERITENONE Leaf400.0 700.0 *
(+)-PIPERITENONE-OXIDE Leaf-- 2900.0 -1.07 *
Activities (1)
Antiacetylcholinesterase IC50=64 ug/ml
(+)-PIPERITONE Leaf-- 1400.0 *
(+)-PULEGONE Leaf1100.0 8400.0 1.64 *
Activities (4)
Antiacetylcholinesterase IC50=136 ug/ml
Antiacetylcholinesterase IC50=0.9 mM
Irritant ZEB
Perfumery ZEB
(+)-PULEGONE Plant-- 25455.0 1.0 *
Activities (4)
Antiacetylcholinesterase IC50=136 ug/ml
Antiacetylcholinesterase IC50=0.9 mM
Irritant ZEB
Perfumery ZEB
(-)-BORNEOL Leaf500.0 600.0 *
Activities (3)
Antiacetylcholinesterase IC38=164 ug/ml
Insect-Repellent
Pesticide
(-)-CARVONE Essential Oil-- -- Jim Duke's personal files.
(-)-CARVONE Leaf-- 7300.0 0.84 *
(-)-LIMONENE Leaf-- 1600.0 0.67 *
(-)-LINALOOL Leaf3900.0 4000.0 0.74 *
(-)-LINALYL-ACETATE Leaf-- -- -1.0 *
(-)-MENTHOL Leaf1500.0 9600.0 -0.14 *
Activities (4)
Antiacetylcholinesterase IC38=164 ug/ml
Antiacetylcholinesterase IC38=1.2 mM
Pesticide
Termiticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
(-)-MENTHOL-ACETATE Leaf10.0 32.0 *
(-)-MENTHONE Leaf500.0 4400.0 -0.41 *
Activities (2)
Antiacetylcholinesterase IC39=164 ug/ml
Antiacetylcholinesterase IC50=1.4 mM
(-)-PIPERITENONE-OXIDE Leaf3330.0 10595.0 *
(-)-PIPERITONE Leaf240.0 7700.0 1.0 *
Activities (1)
Antiacetylcholinesterase IC50=136 ug/ml
1,8-CINEOLE Leaf-- -- Jim Duke's personal files.
Activities (67)
(-)-Chronotropic 87 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 87 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Acaricide LC100=6 uM
Allelopathic
Allergenic
Anesthetic
Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiacetylcholinesterase IC50=41 ug/ml
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacterial 50 ppm
Antibronchitic
Anticariogenic
Anticatarrh Martindale's 29th
Anticholinesterase IC50=50-70
Antifatigue
Antihalitosic American Health, 12(4): 17, 1993.
Antiinflammatory
Antilaryngitic
Antinociceptive
Antipharyngitic
Antiplaque
Antirheumatic
Antirhinitic
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antisinusitic
Antispasmodic
Antistaphylococcic 50 ppm
Antitussive
Antiulcer
CNS-Stimulant
Candidicide
Carcinogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Choleretic
Convulsant
Counterirritant Martindale's 29th
Cytochrome-P450-Inducer
Decongestant
Degranulant 0.3 ul/ml
Dentifrice Martindale's 29th
Edemagenic inj
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 1-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective
Gram(+)icide
Gram(-)icide
Hepatotonic
Herbicide IC50=78 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypotensive
Inflammatory inj
Insectifuge
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Neurotoxic
P450-Inducer
Pediculicide 2.3 x pyrethrin
Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Rubefacient Martindale's 29th
Secretogogue
Sedative
Spasmogenic
Surfactant
Testosterone-Hydroxylase-Inducer
Transdermal
Trichomonicide LD100=1,000 ug/ml
1-P-MENTHEN-3-ONE Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
3',4',5,7-TETRAHYDROXY-FLAVONE-7-ALPHA-L-RHAMNOSYL-BETA-D-GLUCOSIDE Shoot-- -- Jim Duke's personal files.
3',5,7-TRIHYDROXY-4'-METHOXY-FLAVONE-O-BETA-D-GLUCOSIDE Shoot-- -- Jim Duke's personal files.
3(5',5'-DIMETHYL-TETRAHYDROFURAN-2'-YL)-BUT-CIS-2-EN-1-OL Plant-- 1.4 *
3(5',5'-DIMETHYL-TETRAHYDROFURAN-2'-YL)-BUT-CIS-2-EN-1-OL Essential Oil-- 1.4 -0.71 Jim Duke's personal files.
3-METHYLPENTANOL Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
4',5,7-TRIHYDROXY-FLAVONE-7-ALPHA-L-RHAMNOSYL-BETA-D-GLUCOSIDE Shoot-- -- Jim Duke's personal files.
4',5,7-TRIHYDROXY-FLAVONE-O-BETA-D-GLUCOSIDE Shoot-- -- Jim Duke's personal files.
ACACETIN-7-O-BETA-D-GLUCOSIDE Shoot-- -- Jim Duke's personal files.
ACETIC-ACID Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (16)
Acidulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial 5,000 ppm
Antiotitic Martindale's 28th
Antisalmonella
Antivaginitic 1-2%
Expectorant Martindale's 28th
Fungicide Martindale's 29th
Keratitigenic
Mucolytic Martindale's 29th
Osteolytic
Perfumery FEMA 6,000-40,000 ppmAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Protisticide Martindale's 29th
Spermicide Martindale's 28th
Ulcerogenic HerbalGram No. 20, page 9.
Verrucolytic
ACETYLMENTHOL Plant-- -- Chemical Constituents of Oriental Herbs (3 diff. books)
ALPHA,BETA-HEXENIC-ACID Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
ALPHA,GAMMA-HEXENYL-PHENYL-ACETATE Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
ALPHA-PINENE Plant10.0 300.0 -0.27 *
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
ALPHA-THUJENE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
ANISALDEHYDE Shoot-- -- Jim Duke's personal files.
Activities (7)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Fungicide
Insecticide Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
Tyrosinase-Inhibitor ID50=320 uM
Tyrosinase-Inhibitor ID50=0.32 mM
Tyrosinase-Inhibitor ID50=380-970 uM
BETA-CAR-3-ENE Essential Oil-- -- Jim Duke's personal files.
BETA-CARYOPHYLLENE Leaf-- 700.0 0.01 *
BETA-PHELLANDRENE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (3)
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Perfumery Merck 11th Edition
BETA-PINENE Plant10.0 1445.0 1.12 *
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
BETA-PINENE Leaf-- 800.0 0.75 *
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
CALCIUM Plant-- 13500.0 -0.01 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (28)
AntiPMS 1 g/day
Antiallergic 500 mg/day
Antianxiety Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiarrhythmic 500-1,500 mg
Antiarthritic 1,000 mg/day
Antiatherosclerotic 500 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Anticlimacteric 1,000-1,500 mg/day
Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidote (Aluminum) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihypertensive
Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antimenopausal 1,000-1,500 mg/day
Antiobesity
Antiosteoporotic 500-2,000 mg/day
Antiperiodontitic 750 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antirheumatic 1,000 mg/day
Antistress 500-1,500 mg/day
Antitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Anxiolytic 500-1,500 mg/day
Calcium-Channel-Blocker
Diuretic
Hypocholesterolemic 500 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Hypotensive 1 g/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Laxative 1,000-1,200 mg
Tranquilizer 500-1,500 mg/day
Vasodilator
CAMPHENE Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (9)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Jim Duke's personal files.
Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
FLavor FEMA 15-175Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Spasmogenic Fitoterapia No.59-1984.
CAPROIC-ACID Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (1)
Irritant
CARVOMENTHONE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
CARVONE Leaf8100.0 26000.0 5.05 *
Activities (19)
Allergenic
Antiacetylcholinesterase IC50=1.4-1.8 mM
Antiproliferative
Antiseptic 1.5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
FLavor FEMA 80-3,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Trichomonicide LD100=300 ug/ml
Vermicide
CARVONE Essential Oil-- -- Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Activities (19)
Allergenic
Antiacetylcholinesterase IC50=1.4-1.8 mM
Antiproliferative
Antiseptic 1.5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
FLavor FEMA 80-3,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Trichomonicide LD100=300 ug/ml
Vermicide
CARYOPHYLLENE Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CHLOROPHYLL-A Tissue Culture-- -- Jim Duke's personal files.
CHLOROPHYLL-B Tissue Culture-- -- Jim Duke's personal files.
CINEOLE Leaf40.0 1785.0 -0.62 *
CIS-ISOPULEGONE Leaf-- -- Jim Duke's personal files.
CIS-OCIMENE Essential Oil-- -- Jim Duke's personal files.
Activities (3)
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Fungicide Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
COPPER Plant-- 20.0 0.66 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (12)
Antianemic
Antiarthritic
Antidiabetic 2-4 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antifatigue
Antiinflammatory Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antinociceptive Werbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiosteoporotic
Cardioprotective
Contraceptive Martindale's 28th
Hypocholesterolemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Immunomodulator
Schizophrenigenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
D-3-OCTANOL Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
DIOSMETIN-7-O-BETA-D-GLUCOSIDE Shoot-- -- Jim Duke's personal files.
DL-ISOMENTHONE Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
EO Plant-- -- Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
EO Plant10000.0 32100.0 1.7 *
ETHYL-AMYL-CARBINOL Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
EUGENOL Essential Oil-- -- Jim Duke's personal files.
Activities (76)
Acaricide LD50=5.47 ug/sq cm cf DEET at 37.59 ug/sq cm
Allergenic
Analgesic Merck 11th Edition
Anesthetic 200-400Phytotherapy Research, 4: 93.
AntiTNF
Antiaggregant IC50=0.3 uMPhytotherapy Research, 4: 93.
Antiarachidonate
Antibacterial 500 ppmValnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antibacterial MBC=400 ug/ml
Anticonvulsant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic 100Phytotherapy Research, 4: 95.
Antiestrogenic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antigenotoxic 50-500 mg/kg orl mus
Antiherpetic IC50=16.2-25.6 ug/ml
Antiinflammatory (11 uM) IC~97=1,000 uM
Antikeratotic IC50=16.2-25.6 ug/ml
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antinitrosating
Antioxidant IC65=30 ppm
Antioxidant 10 uM
Antiprostaglandin 11 uM
Antiprostaglandin IC50=9.2 mM
Antipyretic 3 ml/man/day
Antiradicular EC50=2 ul/l
Antisalmonella MIC=400 ug/ml
Antiseptic 3 ml/man/day
Antiseptic 400 ug/ml
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antithromboxane Lawrence Review of Natural Products, Jul-87.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer
Antiviral IC50=16.2-25.6 ug/ml
Apifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
COX-1-Inhibitor IC97=1,000 uM
COX-2-Inhibitor IC>97=1,000 uM
COX-2-Inhibitor IC50=129 uM
Calcium-Antagonist IC50=224 uM
Calcium-Antagonist IC50=200 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Phytotherapy Research, 4: 93.
Carcinogenic? Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Choleretic
Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima.
Cytotoxic 25 ug/mlPhytotherapy Research, 4: 93.
Dermatitigenic
Enterorelaxant J. Aromatherapy 4: 22.
FLavor FEMA 10-500Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective 100 ppm
Herbicide
Insecticide
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvicide
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=2,000 ug/mlShoyakugaku Zasshi, 44: 183.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Prostaglandin-Synthesis-Inhibitor 1 mM rbtChen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Prostaglandin-Synthesis-Inhibitor IC50=9.2 uM
Sedative
Termiticide LD100=5 mg/g
Trichomonicide LD100=300 ug/ml
Trichomonistat IC50=10 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer Lawrence Review of Natural Products, Dec-93.
Ulcerogenic Phytotherapy Research, 4: 93.
Varroacide
Vasodilator
Vermifuge
FORMIC-ACID Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (13)
Acaricide
Antiseptic
Antisyncopic
Astringent Merck 11th Edition
Corrosive Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Counterirritant Merck 11th Edition
FLavor FEMA 500-2,500Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Fungitoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Irritant
Pesticide
Preservative Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FURFURAL Plant2.0 5.0 -0.5 Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (6)
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
FLavor FEMA 1-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insecticide
Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
GAMMA-TERPINENE Essential Oil-- -- Jim Duke's personal files.
Activities (11)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC23=1.2 mM
Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Antioxidant Jim Duke's personal files.
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
GAMMA-TERPINENE Leaf-- 900.0 1.36 *
Activities (11)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC23=1.2 mM
Antifeedant Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Antioxidant Jim Duke's personal files.
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
GERMACRENE-D Essential Oil-- -- Jim Duke's personal files.
Activities (2)
Pesticide
Pheromone
GERMACRENE-D Leaf300.0 400.0 -0.2 *
Activities (2)
Pesticide
Pheromone
HESPERIDIN Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (31)
Analgesic
Anti-LDL
AntiDNA
AntiRNA
Antiallergenic Yakugaku Zasshi, 111: 193, 1991.
Antibradykinic Economic & Medicinal Plant Research, 5: 366.
Anticapillary-Fragility
Antiflu Economic & Medicinal Plant Research, 5: 197.
Antihistaminic
Antiinflammatory IC47=50 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antiinflammatory IC63=100 mg/kg scuDa Silva Emim, J.A., Oliveira, A.B. and Lapa, A.J. Pharmacological Evaluation of the Anti-inflammatory Activity of a Citrus Bioflavonoid, Hesperidin, and the Isoflavonoids, Duartin and Claussequinone, in Rats and Mice. J. Pharm. Pharmacol. 46:118-122,1994
Antileukotriene
Antioxidant IC50=8 ppmPhytochemistry, 37: 1463.
Antiprostaglandin
Antistomatitic
Antitriglyceride
Antiulcer 100-150 mg/kg ipr
Antivaccinia Economic & Medicinal Plant Research, 5: 197.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Anxiolytic
CNS-Depressant 100-150 mg/kg ipr
Calcium-Antagonist IC50=1.2 uM rbt
Capillariprotective Martindale's 29th
Catabolic
Choleretic
Cyclooxygenase-Inhibitor
Hypolipidemic
Lipoxygenase-Inhibitor
Pesticide
ProHLDL
Vasopressor
IRON Plant-- 400.0 -0.27 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (6)
Antiakathisic Martindale's 29th
Antianemic Martindale's 29th
Anticanker
Anticheilitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antimenorrhagic 100 mg/day/wmn/orlPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Prooxidant
ISOMENTHOL Essential Oil-- -- Jim Duke's personal files.
Activities (1)
Antiacetylcholinesterase IC29=1.2 mM
ISOMENTHONE Leaf300.0 600.0 -0.48 *
Activities (3)
Antiacetylcholinesterase IC50=1.6 mM
Antioxidant
Antiradicular
ISOPULEGOL Essential Oil-- -- Jim Duke's personal files.
Activities (3)
Antiacetylcholinesterase IC50=2.0 mM
FLavor FEMA 5-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
ISOPULEGONE Leaf240.0 770.0 -1.41 *
Activities (4)
FLavor FEMA 5-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hepatotoxic
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pulmonotoxic
ISOVALERALDEHYDE Plant-- -- Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (1)
FLavor FEMA 0.5-5Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
ISOVALERIC-ACID Plant30.0 90.0 1.0 Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
Activities (5)
FLavor FEMA 1-16Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Merck 11th Edition
Sedative
Tranquilizer Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
KETONES Plant336.0 1008.0 Guenther, E., The Essential Oils, 6 volumes, D. van Nostrand, New York, 1948-1952.
L-MENTHOL Plant373.0 29515.0 *
Activities (3)
Antiacetylcholinesterase IC38=164 ug/ml
FLavor FEMA 35-1,200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery 5,000-25,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
L-MENTHYL-ACETATE Plant85.0 4815.0 *
Activities (2)
FLavor FEMA 5-25Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
LIMONENE Leaf20.0 3520.0 3.26 *
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
LINALOL Leaf-- -- Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
LINALOL-ACETATE Leaf690.0 2215.0 Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
LINALOOL Leaf-- -- Jim Duke's personal files.
Activities (53)
Acaricide C90=<15 ul/l (=<15 ppm
Allergenic
Analgesic
Anesthetic 0.01-1 ug/ml
Antiacetylcholinesterase
Antiallergic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antianaphylactic
Antibacterial MIC=1,600 ug/ml
Anticariogenic MIC=1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticolic
Anticonvulsant 200 mg/kg ipr mus
Antiedemic
Antiglutamaergic
Antihistaminic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory
Antileukemic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antilymphomic IC50=3.5-4.2 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimange
Antimite
Antimutagenic
Antiseptic 5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antishock Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antiviral
Barbituate-Synergist
Bronchorelaxant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
CNS-Depressant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative
Culicide LC50=156-194 mg/l
Cytotoxic
Expectorant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
FLavor FEMA 2-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Acta Botanica Sinica, 32: 49.
GABA-nergic
Hypnotic
Hypothermic
Insecticide LC50=156-194 mg/l
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide LC50=156-194 mg/l
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Prooxidant Charalambous, G. (Ed.). 1994. Spices, Herbs and Edible Fungi. Elsevier Science B. V. Amsterdam. 764 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Sedative 200 mg/kg ipr mus (1% as active as diazepam)
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Trichomonicide LD100=600 ug/ml
Tumor-Promoter
LINALOOL-ACETATE Leaf690.0 2215.0 *
LUTEOLIN Shoot-- -- Jim Duke's personal files.
Activities (78)
Aldose-Reductase-Inhibitor EC=3 ppmShin*, K.H., Chung, M.S., Chae, Y.J., Yoon, K.Y., Cho, T.S. 1992. A survey for aldose reductase inhibition of herbal medicines. Fitoterapia 64(2): 130, 1993.
Aldose-Reductase-Inhibitor IC50=0.45 uM rat
AntiHIV
Antiallergic
Antiangiogenic IC60-75=10 uM
Antiatherogenic
Antibacterial MIC=500 ug/mlPlanta Medica, 57: A43, 1991.
Anticarcinogenic
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticataract EC=3 ppmShin*, K.H., Chung, M.S., Chae, Y.J., Yoon, K.Y., Cho, T.S. 1992. A survey for aldose reductase inhibition of herbal medicines. Fitoterapia 64(2): 130, 1993.
Anticomplementary
Antidermatic Bisset, N.G., ed. 1994. Herbal Drugs and Phytopharmaceuticals. CRC Press. Boca Raton, FL. 566 pp.
Antiestrogenic
Antifeedant IC52=<1,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antiherpetic 11-23 ug/ml
Antihistaminic <10-15 uM
Antiinflammatory #NAME?Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antileukemic 20-50 uM
Antilymphomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimelanomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimutagenic ID50=2-5 nM
Antimutagenic ID50=0.44 ug/ml
Antinociceptive
Antioxidant IC50=10 uM
Antipolio Economic & Medicinal Plant Research, 5: 197.
Antiproliferant
Antispasmodic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antitumor 1-50 uM
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Ovary) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Skin) 20 uM
Antitumor (Stomach) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Thyroid) 12-50 uM
Antitumor (brain) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitussive
Antiviral 11-23 ug/ml
Aphidifuge
Apoptotic 12-50 uM
Aromatase-Inhibitor IC35=1 uM/lJournal of Medicinal Food 2: 235.1999.
Beta-Glucuronidase-Inhibitor IC50=~40 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive
Chemopreventive
Choleretic
Cytotoxic 1-50 uM
Deiodinase-Inhibitor Jim Duke's personal files.
Differentiator IC>40=40 uM
Diuretic Jim Duke's personal files.
Estrogenic 58% genistein
Hepatoprotective
Hyaluronidase-Inhibitor IC50+=100-250 uM
Hypocholesterolemic
ICAM-1-Inhibitor
IKK-Inhibitor
Iodothyronine-Deiodinase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lipoxygenase-Inhibitor
MAPK-Inhibitor
MMP-9-Inhibitor 20 uM
Metalloproteinase-Inhibitor
Myorelaxant
NEP-Inhibitor IC50=>42 uM
NF-kB-Inhibitor
NO-Inhibitor
PTK-Inhibitor 10-100 uM
Pesticide
Proliferant
Prostaglandin-Synthetase-Inhibitor
Protein-Kinase-C-Inhibitor IC70=50 uM
Succinoxidase-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
TNF-alpha-Inhibitor IC50=14.44 uM
Topoisomerase-I-Inhibitor Santti, R., Makela, S., Strauss, L., Korman, J., Kostian, M. L. 1998. Phytoestrogens: Potential Endocrine Disruptors in Males. Toxicol Ind Health, 14: 223-237.
VEGF-Inhibitor IC50=2-7 uM
Vasodilator
Xanthine-Oxidase-Inhibitor IC50=0.11 ug/mlChem. & Pharm. Bull. 38: 1772.
iNOS-Inhibitor
MAGNESIUM Plant-- 2830.0 -0.38 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (65)
AntiCFS
AntiLyme 400-1,000 mg
AntiMS
AntiPMS 400-800 mg/day/wmn/orl
AntiPMS 400-800 mg/day/wmn orl
AntiRaynaud's 280-350 mg/day
Antiaggregant 400 mg/day
Antialcoholic
Antianginal 400 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antianorectic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antianxiety 400 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiarrhythmic 400 mg/day
Antiarthritic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiasthmatic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiatherosclerotic 400 mg/day
Anticephalagic
Anticlimacteric 500-750 mg/day
Anticonvulsant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp.
Anticoronary 400 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidiabetic 400-800 mg/man/day
Antidysmenorrheic 100 mg 4 x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiendometriotic 500 mg/day
Antienterotic
Antiepileptic 450 mg/day
Antifatigue
Antifibromyalgic 200-300 mg 3x/day
Antigastrotic
Antiglaucomic
Antihyperkinetic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihypertensive
Antihypoglycemic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiinflammatory 100 mg 4 x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antilithic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antimastalgic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antimenopausal 500-750 mg/day
Antimigraine 200 mg/day/manWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antimitral-valve-prolapse
Antinephrolytic
Antineurotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiosteoporotic 500-1,000 mg/day/wmn/orl
Antiplaque 500-1,000 mg/day
Antiretinopathic 400 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antispasmodic
Antispasmophilic 500 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antistress 500-750 mg/day
Antistroke 400 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antisyndrome-X 400 mg/man/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Anxiolytic 500-750 mg/day
CNS-Depressant Facciola, S. 1998. Cornucopia - A Source Book of Edible Plants. Kampong Publications, Vista CA. 713 pp.
Calcium-Antagonist
Cardioprotective
Diuretic
Hypocholesterolemic 400 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Hypotensive 260-500 mg/day
Immunomodulator
Insulinogenic 400 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Laxative 300-500 mg/day
Litholytic
Myorelaxant 100 mg 4 x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Neurotransmitter
Tranquilizer 500-750 mg/day
Uterorelaxant 100 mg 4 x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Vasodilator
MANGANESE Plant-- 44.0 -0.38 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (14)
AntiPMS
Antialcoholic Forest H. Nielsen, USDA, Grand Forks, various publications.
Antianemic Martindale's 28th
Antiarthritic
Antidiabetic 3-5 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antidiabetic 10-30 mg/man/day
Antidiscotic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidyskinetic Martindale's 28th
Antiepileptic 450 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiosteoporotic
Antiototic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antioxidant
Antisyndrome-X 10-30 mg/man/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Hypoglycemic 10-30 mg/man/day
MENTHOFURAN Plant4200.0 12600.0 1.69 *
Activities (5)
Calcium-Antagonist IC50=441 uM gpg (weak activity)
Hepatotoxic Lawrence Review of Natural Products, Jan-92.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Pulmonotoxic De Smet, P.A.G.M., Keller, K., Hansel, R. and Chandler, R.F., eds. 1993. Adverse Effects of Herbal Drugs 2. Springr-Verlag, Berlin. 348pp.
MENTHOFUROLACTONE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
MENTHOL Leaf1000.0 24385.0 2.22 *
Activities (63)
Allergenic Martindale's 29th
Analgesic Martindale's 28th
Anesthetic 2,000 ppmYamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Antiacetylcholinesterase IC50=2.0 mM
Antiaggregant IC50=750
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antiasthmatic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antibacillus MIC=1.25 mg/ml
Antibacterial MIC=0.625-2.5
Antibronchitic Martindale's 28th
Antidandruff A.L.L. Hunting. Encyclopedia of Shampoo Ingredients. Micelle Press, Cranford NJ. 467 pp.
Antiescherichic MIC=1.25 mg/ml
Antihalitosic American Health, 12(4): 17, 1993.
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Antiinflammatory Martindale's 28th
Antilisteria MIC=0.625 mg/ml
Antineuralgic
Antiodontalgic Martindale's 28th
Antipruritic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Antipyretic
Antirheumatic Martindale's 28th
Antisalmonella MIC=0.625 mg/ml
Antiseptic 4 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antisinusitic Martindale's 28th
Antispasmodic ED50=0.01 mg/mlFitoterapia No.59-1984.
Antistaphylococcic MIC=0.625 mg/ml
Antistreptococcic MIC=0.4 mg/ml
Antitartar
Antivaginitic
Antivulvitic
Bradycardic 65 mg/3 x day/womanMartindale's 28th
Bronchomucolytic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
Bronchomucotropic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Bronchorrheic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 200.
CNS-Depressant
CNS-Stimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calcium-Antagonist
Candidicide MIC=0.625 mg/ml
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Choleretic
Ciliotoxic Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Congestant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Counterirritant
Decongestant? 11 mg/manEccles, R., et al. 1989. The effects of oral administration of (-)-menthol on nasal resistance to airflow and nasal sensation of airflow in subjects suffering from nasal congestion associated with the common cold. J. Pharm. Pharmacol. 42: 652-654, 1990.
Dermatitigenic
Diaphoretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Enterorelaxant J. Aromatherapy 4: 22.
Expectorant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Gastrosedative Merck 11th Edition
Irritant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Myorelaxant Martindale's 29th
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Neurodepressant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Neuropathogenic 40-100 mg/day/ratYamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Nociceptive Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Perfumery Merck 11th Edition
Pesticide
Refrigerant Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Rubefacient
Termiticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Transdermal
Vibriocide
MENTHOL-ACETATE Leaf60.0 2215.0 1.0 *
MENTHONE Plant71.0 24000.0 3.41 *
Activities (30)
Acaricide
Allelopathic
Analgesic
Antiacetylcholinesterase IC50=1.4 mM
Antiaggregant IC50=750
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacillary MIC=1.25 mg/ml
Antibacterial MIC=0.625-5 mg/ml
Antiescherichic MIC=5 mg/ml
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Antilisteria MIC=1.25 mg/ml
Antisalmonella MIC=5 mg/ml
Antiseptic 2.25 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antispasmodic ED50=0.044 mg/mlFitoterapia No.59-1984.
Antistaphylococcic MIC=0.625-2.5 mg/ml
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide MIC=2.5 mg/ml
Cerebrotoxic orl manJ. Aromatherapy 4: 24.
Culicide LC50=156-194 mg/l
FLavor FEMA 5-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insecticide LC50=156-194 mg/l
Larvicide LC50=156-194 mg/l
Mutagenic
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Psychoactive
Sedative Ortiz de Urbina, A.V., Martin*, M.L., Montero, M.J., Moran, A., and San Roman, L. 1988. Sedating and Antipyretic Activity of the Essential Oil of Calamintha sylvatica subsp. Ascendens. Journal of Ethnopharmacology, 25: 165-171, 1989.
Trichomonicide LD100=600 ug/ml
MENTHONE Leaf250.0 25680.0 2.61 *
Activities (30)
Acaricide
Allelopathic
Analgesic
Antiacetylcholinesterase IC50=1.4 mM
Antiaggregant IC50=750
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacillary MIC=1.25 mg/ml
Antibacterial MIC=0.625-5 mg/ml
Antiescherichic MIC=5 mg/ml
Antihistaminic J. Food Hyg. Soc. Jap. 33(6): 569.
Antilisteria MIC=1.25 mg/ml
Antisalmonella MIC=5 mg/ml
Antiseptic 2.25 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antispasmodic ED50=0.044 mg/mlFitoterapia No.59-1984.
Antistaphylococcic MIC=0.625-2.5 mg/ml
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide MIC=2.5 mg/ml
Cerebrotoxic orl manJ. Aromatherapy 4: 24.
Culicide LC50=156-194 mg/l
FLavor FEMA 5-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insecticide LC50=156-194 mg/l
Larvicide LC50=156-194 mg/l
Mutagenic
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Psychoactive
Sedative Ortiz de Urbina, A.V., Martin*, M.L., Montero, M.J., Moran, A., and San Roman, L. 1988. Sedating and Antipyretic Activity of the Essential Oil of Calamintha sylvatica subsp. Ascendens. Journal of Ethnopharmacology, 25: 165-171, 1989.
Trichomonicide LD100=600 ug/ml
MENTHONONE Plant-- -- Chemical Constituents of Oriental Herbs (3 diff. books)
MYRCENE Leaf10.0 2485.0 0.72 *
Activities (22)
ACE-Inhibitor 100 ug/ml
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allergenic
Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antibacterial
Anticonvulsant
Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antinitrosaminic
Antinociceptive 10-20 mg/kg ipr musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antinociceptive 20-40 mg/kg scu musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antioxidant Jim Duke's personal files.
Antispasmodic Jim Duke's personal files.
Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMA 0.5-9Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypothermic
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Myorelaxant 100-200 mg/kg
P450-2B1-Inhibitor IC50=0.14 uM
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
NEOISOMENTHOL Essential Oil-- -- Jim Duke's personal files.
NEOISOPULEGONE Essential Oil-- -- Jim Duke's personal files.
OCTAN-3-OL Leaf-- 10200.0 2.44 *
P-CYMENE Leaf9.0 29.0 -0.38 *
Activities (16)
Analgesic Martindale's 28th
Antiacetylcholinesterase IC40=1.2 mM
Antibacillary
Antibacterial
Antiflu
Antirheumatalgic Martindale's 28th
Antiviral
FLavor FEMA 12-250Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Herbicide IC50=50 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Laxative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide LD100=50 ug/ml
P-CYMOL Leaf562.0 1800.0 0.16 *
P-MENTHAN-TRANS-2,5-DIOL Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
PIPERITENONE Plant-- -- Chemical Constituents of Oriental Herbs (3 diff. books)
Activities (3)
Antiacetylcholinesterase IC50=110 ug/ml
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Toxic 10,000/manAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
PIPERITENONE-OXIDE Leaf260.0 7320.0 0.88 *
Activities (2)
Insecticide Shah, G.C., Bhandari, R. & Mathela, C.S. 1992. 1,2-Epoxy-p-Menthane Derivatives from some Labiatae Species. J. Ess. Oil Res. 4: 57-59.
Pesticide
PIPERITONE Leaf240.0 7700.0 3.7 Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Activities (7)
Antiasthmatic
FLavor FEMA 1-2Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=75 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge (> DEET)Bowers, W.S., Ortego, F., You, X., and Evans, P.H. Insect Repellents From The Chinese Prickly Ash Zanthoxylum bungeanum. Journal of Natural Products, 56(6): 935-938, 1993.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
PIPERITONE Leaf13.0 1285.0 0.32 *
Activities (7)
Antiasthmatic
FLavor FEMA 1-2Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=75 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge (> DEET)Bowers, W.S., Ortego, F., You, X., and Evans, P.H. Insect Repellents From The Chinese Prickly Ash Zanthoxylum bungeanum. Journal of Natural Products, 56(6): 935-938, 1993.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
PIPERITONE-OXIDE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
PIPERITONE-OXIDE Leaf320.0 5135.0 0.5 *
POTASSIUM Plant-- 35100.0 0.93 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (14)
Angiotensin-Receptor-Blocker
Antiarrhythmic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidepressant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antifatigue Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihypertensive
Antispasmodic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antistroke
Anxiolytic
Beta-Blocker
Cardioprotective 3,000-5,000 mg
Cardiotoxic 18,000 mg/man/day
Diuretic
Hypotensive
Vasodilator
PULEGONE Plant100.0 24960.0 2.12 *
Activities (28)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiacetylcholinesterase IC50=0.9 mM
Antiacetylcholinesterase IC50=136 ug/ml
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antibacterial Economou, D., and Nahrstedt, A. 1991. Chemical, Physiological, and Toxicological Aspects of the Essential Oil of Some Species of the Genus Bystropogon*. Planta Medica, 57: 347, 1991.
Anticholinesterase Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antihistaminic Ortiz De Urbina, A.V., Martin, M.L., Montero, M.J., Carron, R., Sevilla, M.A., San Roman, L. 1989. Antihistaminic activity of pulegone on the guinea-pig ileum. J. Pharm. Pharmacol. 42: 295-296, 1990.
Antipyretic
Avifuge
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Economou, D., and Nahrstedt, A. 1991. Chemical, Physiological, and Toxicological Aspects of the Essential Oil of Some Species of the Genus Bystropogon*. Planta Medica, 57: 347, 1991.
Cerebrotoxic orl manJ. Aromatherapy 4: 24.
Encephalopathic 80 mg/kg orl ratLawrence Review of Natural Products, Jan-92.
FLavor FEMA 5-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Economou, D., and Nahrstedt, A. 1991. Chemical, Physiological, and Toxicological Aspects of the Essential Oil of Some Species of the Genus Bystropogon*. Planta Medica, 57: 347, 1991.
Glutathionalytic Lawrence Review of Natural Products, Jan-92.
Hallucinogenic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Hepatotoxic Lewis, E.J. and Friedrich, E.C. 1989. The Essential Oil of Poliomintha incana. Planta Medica 56(2): 224-226, 1990.
Herbicide IC50=1.5 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Insectifuge
Nephrotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Neurotoxic
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Pulifuge
Pulmonotoxic
Sedative
RAFFINOSE Plant-- -- Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Activities (1)
Flatugenic Singh, J., Gupta, K., and Arora, S.K. 1993. Changes in the anti-nutritional factors of developing seeds and pod walls of fenugreek (Trigonella foenum graecum L.). Plant Foods for Human Nutrition. 46: 77-84, 1994.
RESIN Plant-- -- Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
ROSMARINIC-ACID Plant-- 28000.0 -0.02 Fitoterapia No.62: 166.
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
ROSMARINIC-ACID Leaf71.0 228.0 -0.98 *
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
SABINENE-HYDRATE Leaf30.0 160.0 -0.37 *
SANTENE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
SH Plant-- -- *
SODIUM Plant-- 860.0 -0.26 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (1)
Hypertensive Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
STACHYOSE Plant-- -- Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Activities (1)
Flatugenic Singh, J., Gupta, K., and Arora, S.K. 1993. Changes in the anti-nutritional factors of developing seeds and pod walls of fenugreek (Trigonella foenum graecum L.). Plant Foods for Human Nutrition. 46: 77-84, 1994.
TANNIN Plant-- -- Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Activities (35)
Anthelmintic
AntiHIV
Antibacterial
Anticancer
Anticariogenic
Antidiarrheic
Antidysenteric
Antihepatotoxic
Antihypertensive
Antilipolytic
Antimutagenic
Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC50=1.44 ug/ml
Antioxidant 1/3 quercetin
Antiradicular 500 mg/kg/day orl musUchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antitumor
Antitumor-Promoter
Antiulcer
Antiviral
Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14.
Carcinogenic
Chelator
Cyclooxygenase-Inhibitor
Glucosyl-Transferase-Inhibitor
Hepatoprotective
Immunosuppressant
Lipoxygenase-Inhibitor
MAO-Inhibitor
Ornithine-Decarboxylase-Inhibitor
Pesticide
Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
THUJONE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (17)
Abortifacient Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antibacterial J. Ess. Oil Res. 7: 271.
Antiseptic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antispasmodic ED50=0.127 mg/mlFitoterapia No.59-1984.
Cerebrodepressant
Convulsant 40 mg/kgR.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Counterirritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Emmenagogue Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Epileptigenic
Hallucinogenic
Herbicide IC50=22 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Neurotoxic
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Respirainhibitor
Toxic Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
TRANS-ISOPULEGONE Leaf-- -- Jim Duke's personal files.
TRANS-OCIMENE Essential Oil-- -- Jim Duke's personal files.
ZINC Plant-- 28.0 -0.24 Suziki, A., Morimoto, I., and Okitzu, T., Elution of Metals from Crude Drugs, Shoykugaku Zasshi 36(3):190-195.
Activities (77)
ACE-Inhibitor
Analgesic
AntiBPH 25-60 mg/day
AntiCrohn's Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
AntiHIV
Antiacne 135 mg/day
Antiacrodermatitic 8-34 mg/day/orl/chdMartindale's 29th
Antialcoholic
Antialopecic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antialzheimeran 50 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiangiogenic
Antianorexic Martindale's 29th
Antiarthritic 50 mg/3x/day/orl/man
Anticanker 100 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Anticataract 30 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Anticoeliac Martindale's 28th
Anticold 50 mgDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Anticolitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Anticoronary 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antidandruff Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidementia
Antidiabetic 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antidote (Cadmium) Let's Live, May 1989.
Antidysgeuzic
Antieczemic 150 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiencephalopathic Martindale's 29th
Antiepileptic 100 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antifibrotic 30 mg
Antifuruncular 45 mg/3x/day/manMartindale's 28th
Antihangover 15 mg
Antiherpetic? 25-60 mg/day
Antiimpotence Martindale's 29th
Antiinfective 50 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiinfertility 60 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiinsomniac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antilepric Martindale's 29th
Antileukonychic
Antilymphomic
Antimaculitic
Antimetastatic
Antineuropathic
Antinyctalopic
Antiobesity 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antiosteoporotic
Antiperiodontitic
Antiplaque Martindale's 29th
Antiprolactin Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiprostatitic 50 mg/man/day/orlPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antirheumatic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiseptic 50 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antispare-Tire 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antistomatitic 50 mg/man/3x/dayMartindale's 28th
Antisyndrome-X 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antitinnitic 60-120 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antitriglyceride 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antiulcer 50 mg/3x/day/manMartindale's 28th
Antiulcer 88 mg/rat/day/15 days
Antiviral? Martindale's 29th
Astringent Martindale's 28th
Collagenic
Copper-Antagonist Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Deodorant Martindale's 29th
Detoxicant (Alcohol)
Ergogenic
Hypotensive 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Immunomodulator
Immunostimulant Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Immunosuppressant 300 mg/day/6 wks/orl/manMartindale's 29th
Insulinogenic 30 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Leptingenic 30-60 mg/man/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Mucogenic Li, K.M. Effect of zinc sulphate on acetic acid-induced gastric ulceration in rats. J. Pharm. Pharmacol. 42: 657-659, 1990.
NF-kB-Inhibitor
Pesticide
Spermigenic 60 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Testosteronigenic 60 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Trichomonicide Martindale's 29th
Vulnerary Martindale's 28th
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.