Data Views Exclude Ubiquitous Chemicals

Paginate
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Chemical Low PPM High PPM StdDev *Reference
BETULIN Root-- -- Jim Duke's personal files.
Activities (13)
AntiHIV 6.1 uM
Anticarcinomic
Antifeedant
Antiflu
Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 6.1 uM
Aphidifuge Lugemwa, F.N., Huang, F-Y., Bentley, M.D., Mendel, M.J., and Alford, A.R. 1990. A Heliothis zea Antifeedant from the Abundant Birchbark Triterpene Betulin. J. Agric. Food Chem. 38(2): 493-494.
Cytotoxic 600 ppm
Cytotoxic 8.6 uM
Hypolipemic
Prostaglandin-Synthesis-Inhibitor IC50=119 uMHuang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
Topoisomerase-II-Inhibitor IC50=38.6 uM
BETULINIC-ACID Root-- -- Jim Duke's personal files.
Activities (22)
Anthelmintic
AntiHIV EC50=2.0 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/ml
AntiHIV 14.8 uM
Antibacterial
Anticancer Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic
Antiinflammatory Recio, M., et al. 1994. Investigations on the Steroidal Anti-Inflammatory Activity of Triterpenoids from Diospyros leucomelas*. Planta Medica, 61: 9.
Antileukemic
Antimalarial IC50=19-26 ug/ml
Antimelanomic New York Times, 3/28/95.
Antinociceptive
Antiplasmodial IC50=19-26 ug/ml
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral 14.8 uM
Apoptotic
Cytotoxic 50-100 ppmBiosyn. Prod. Cancer Chemotherapy (Petit et al)
Cytotoxic 16.4 uM
Phospholipase-A2-Inhibitor
Prostaglandin-Synthesis-Inhibitor 200 ug/mlDunstan, C. A., Liu, B., Welch, C. J., Perera, P., Bohlin, L. 1998. Alphitol, a Phenolic Substance from Alphitonia zizyphoides which Inhibits Prostaglandin Biosynthesis in vitro. Phytochemistry, 48(3): 495-497.
Prostaglandin-Synthesis-Inhibitor IC50=101 uMHuang, C., Tunon, H., Bohlin, L. 1995. Anti-Inflammatory Compounds Isolated from Menyanthes trifoliata L. Yao Hsueh Hsueh Pao, 30(8): 621-626.
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.