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Activities: 337
All Chemicals: 24
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Chemical Low PPM High PPM StdDev *Reference
ROSMARINIC-ACID Plant-- 37000.0 0.52 Fitoterapia No.62: 166.
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
RESIN Plant-- 29000.0 -0.72 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
FLAVONOIDS Plant-- 23000.0 1.26 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
ALKALOIDS Plant-- 2400.0 -0.37 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
EO Plant500.0 2000.0 -0.59 *
COUMARIN Plant-- 1200.0 -0.39 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (57)
Aldose-Reductase-Inhibitor 10 ug/ml cow (weak activity, 11% inhibition)Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Allelochemic IC100=2 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Analgesic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Anesthetic
Antiaggregant
Antiandrogenic Planta Medica, 56(6): 671, 1990.
Antibrucellosic Gawron, A., Gorski*, G., Glowniak**, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990.
Anticancer (Kidney) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Anticancer (Prostate) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antidiuretic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antiesherichic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antilymphedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimelanomic 50 mg/day
Antimetastatic 50 mg/man/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimitotic Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7.
Antimononuccleotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antimycoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antipsittacotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antipsoriac Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7.
Antitoxoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antitumor 50 mg/day
Antitumor (GI)
Antitumor (Kidney) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antitumor (Prostate) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Bacteristat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Bruchiphobe
Cancer-Preventive 5-25 ug/mlGawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Carcinogenic 200 mg/kg orl musMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Cardiodepressant
Cardiotonic
Chemopreventive
DME-Inhibitor IC50=57.5 uMAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
Emetic
Estrogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hemorrhagic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatotoxic 0.8-1.71 mM/kg orl rat
Hepatotoxic 2,500 ppm diet
Hepatotoxic 100 mg/kg dog
Hypnotic Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
Hypoglycemic 250-1,000 mg/kg orlEconomic & Medicinal Plant Research, 6: 165
Immunostimulant
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lymphocytogenic 100 mg/dayGawron, A., Gorski*, G., Glowniak**, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990.
Lymphokinetic
Narcotic
Ovicide
Pesticide
Phagocytotic Planta Medica, 56(6): 671, 1990.
Piscicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Respirodepressant
Rodenticide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sedative Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
CARYOPHYLLENE Plant-- 125.0 -0.41 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
TRANS-BETA-FARNESENE Plant-- 85.0 -0.39 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (2)
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
GERMACRENE-D Plant-- 22.0 -0.4 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (2)
Pesticide
Pheromone
CARYOPHYLLENE-OXIDE Plant-- 16.0 -0.38 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (8)
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Calcium-Antagonist ED50=32 uM gpg
Fungicide
Insecticide Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Pesticide
DELTA-CADINENE Plant-- 10.0 -0.49 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (9)
Aldose-Reductase-Inhibitor
Antiacne
Antibacterial MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticariogenic MIC800 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antistreptococcic
Cytochrome-P450-Inducer
P450-Inducer
Pesticide
Testosterone-Inducer
LUTEOLIN-7-MONOGLUCOSIDE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
CHLOROGENIC-ACID Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (77)
Aldose-Reductase-Inhibitor IC50=1.8 uM rat (strong activity)Yoshikawa, M., et al. 1999. Medicinal Flowers. I. Aldose Reductase Inhibitors and Three New Eudesmane-Type Sesquiterpenes, Kikkanols A, B, and C, From the Flowers of Chrysanthemum inducum L. Chem Pharm Bull, 47(3): 340-345.
Allelochemic
Allergenic
Analgesic
AntiEBV Economic & Medicinal Plant Research, 6: 189.
AntiHIV Economic & Medicinal Plant Research, 6: 189.
AntiLegionella
Antiatherosclerotic
Antibacterial
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidiabetic
Antifeedant
Antigenotoxic
Antigonadotropic Jim Duke's personal files.
Antihemolytic 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatotoxic
Antiherpetic Economic & Medicinal Plant Research, 5: 194.
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukotriene
Antimelanogenic
Antimutagenic
Antinitrosaminic
Antioxidant IC53=200 ppmHuang, M-T., and Ferraro, T. Phenolic Compounds in Food and Cancer Prevention. Phenolic Compounds in Food and Their Effects on Health, Ch.2 p.21.
Antioxidant IC80=12 uM
Antioxidant IC50=54.2 uM
Antiperoxidant IC50=36 uMPlanta Medica, 57: A54, 1991.
Antipolio Jim Duke's personal files.
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 9 x quercetin
Antiseptic
Antisunburn
Antithyroid Jim Duke's personal files.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC25=10 uM
Antiulcer Economic & Medicinal Plant Research, 6: 189.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Autotoxic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
CNS-Stimulant 1/6 Caffeine
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Clastogenic Friedman, M. and Dao, L. 1990. Effect of Autoclaving and Conventional and Microwave Baking on the Ergot Alkaloid and Chlorogenic Acid Contents of Morning Glory (Ipomoea tricolor Cav. cv.) Heavenly Blue Seeds. J. Agric. Food Chem. 38: 805-808.
Collagen-Sparing
Diuretic
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Histamine-Inhibitor
Hypoglycemic
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Interferonogenic Economic & Medicinal Plant Research, 1: 124.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC23=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
NO-Genic
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Oviposition-Stimulant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sunscreen
Sweetener Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Vulnerary
LITHOSPERMIC-ACID Root-- -- Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Activities (3)
Antigonadotrophic Jim Duke's personal files.
Antithyroid Jim Duke's personal files.
Cardiotonic
GLUCOSE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (7)
Acetylcholinergic
Antiedemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Merck 11th Edition
Antiketotic Merck 11th Edition
Antivaricose Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hyperglycemic Merck 11th Edition
Memory-Enhancer Science News, 138: 189, 1990.
CAFFEIC-ACID Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (102)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allergenic
Analgesic
AntiHIV EC50=200 ug/ml
AntiLegionella
Antiadenoviral Economic & Medicinal Plant Research, 5: 207.
Antiaggregant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiaging
Antiatherogenic
Antibacterial
Anticancer
Anticarcinogenic Economic & Medicinal Plant Research, 6: 189.
Antidepressant
Antiedemic Economic & Medicinal Plant Research, 6: 189.
Antielastase IC50=93 um/l
Antielastase IC50=86 ug/ml (475 uM)
Antiescherichic
Antiflu Economic & Medicinal Plant Research, 5: 207.
Antigonadotropic Jim Duke's personal files.
Antihemolytic 25 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antihepatoadenomic 200 ppm diet orl mus
Antihepatotoxic
Antiherpetic 50 ug/ml
Antiherpetic EC50=>50 ug/ml
Antihistaminic
Antihypercholesterolemic Economic & Medicinal Plant Research, 6: 189.
Antihyperthyroid
Antiinflammatory
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene
Antimelanogenic
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antiophidic
Antioxidant 50 uM
Antioxidant IC57=30 ppm
Antioxidant 1/3 quercetin
Antioxidant 30 mM
Antioxidant 1.3 x Vit. E
Antioxidant 1/2 BHA
Antiperoxidant IC50=44 uMPlanta Medica, 57: A54, 1991.
Antiperoxidant IC35=200 ug/ml
Antiperoxidant IC85=100 ug/ml
Antiproliferant Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiprostaglandin
Antiradicular 10 uMOhnishi, M., Morishita, H., Iwahashi, H., Toda, S., Shirataki, Y., Kimura, M., and Kido, R. 1993. Inhibitory Effects of Chlorogenic Acids on Linoleic Acid Peroxidation and Haemolysis. Phytochemistry. 36(3): 579-583. 1994.
Antiradicular 1/3 quercetin
Antiradicular 30 mM
Antiradicular IC50=32-35 uM
Antiseptic
Antispasmodic EC50=3.4-15 uMPhytotherapy Research, 4: 73.
Antistaphylococcic
Antistomatitic Economic & Medicinal Plant Research, 5: 207.
Antisunburn
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithyroid Jim Duke's personal files.
Antitumor 200 ppm diet orl mus
Antitumor (Skin)
Antitumor-Promoter IC42=10 uMCancer Research, 48: 5941.
Antiulcerogenic
Antivaccinia Economic & Medicinal Plant Research, 5: 207.
Antiviral IC50=62.5 ug/ml
Anxiolytic
CNS-Active Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
COX-2-Inhibitor IC32=100 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carcinogenic 2% (diet)
Chemopreventive
Cholagogue Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Clastogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Co-carcinogenic
Collagen-Sparing
Cytoprotective Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Cytotoxic TC50=200 ug/ml
DNA-Active Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
DNA-Protective
Diuretic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Fungicide MIC=0.4 mg/ml
Hepatocarcinogenic 400 ppm diet orl mus (in the absence of alcohol)
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 210.
Hepatotropic
Histamine-Inhibitor
Immunostimulant
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Leukotriene-Inhibitor
Lipoxygenase-Inhibitor IC27=5 mMOszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
Lipoxygenase-Inhibitor IC50=62-148 uM
Lyase-Inhibitor IC50=94-164 uM
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Prooxidant
Prostaglandigenic
Sedative 500 mg
Sunscreen IC50=2.5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC91=5 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Sunscreen IC98=25 mg/lLazarova*, G., Kostova, I., Neychev, H. 1992. Photodynamic damage prevention by some hydroxycoumarins. Fitoterapia 64(2): 134-136, 1993.
Tumorigenic Jim Duke's personal files.
Vulnerary
Xanthine-Oxidase-Inhibitor IC50=39.21 uMMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
ASCORBIC-ACID Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (112)
Acidulant FEMA 6,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Aldose-Reductase-Inhibitor Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Analgesic 5-10 g/day
Angiotensin-Receptor-Blocker
AntiAGE 2,000 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
AntiCFS 500-1,000 mg
AntiCTS 1,000 mg 3x/day
AntiCrohn's 50-100 mg/day/orl/manMartindale's 29th
AntiLyme 500-2,000 mg
AntiRaynaud's 500 mg 1-2x/day
Antiaggregant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antiaging 400 mg/day
Antiallergic
Antialzheimeran 2,000-6,000 mg/day
Antiarthritic 0.2-1 g/day
Antiasthmatic 1,000 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiatherosclerotic
Antibacterial Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Anticataract 350 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Anticataract 400 mg/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Anticataract 1 g 3x/day
Anticervicaldysplasic 1,000-2,000 mg/day
Anticlimacteric 500-5,000 mg/day
Anticold 1-2 g/man/day
Antidecubitic 500 mg/man/2x/dayMartindale's 28th
Antidementia
Antidepressant 2,000 mg/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antidiabetic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antidote (Aluminum) Economic & Medicinal Plant Research, 6: 189.
Antidote (Cadmium) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidote (Lead) Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antidote (Paraquat) Martindale's 28th
Antieczemic 3.5-5 g/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiedemic 1 g/man/dayDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiencephalitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiendometriotic 2,000 mg/day
Antifatigue 500-1,000 mg
Antifibrotic 1,000-2,000 mg
Antigallstone 1,000-3,000 mg/day
Antigastritic
Antigingivitic
Antiglaucomic 2 g/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antihangover 1,000 mg
Antihemorrhagic 1 g/man/dayDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihepatitic 2-6 g/man/dayDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antihepatotoxic Economic & Medicinal Plant Research, 6: 189.
Antiherpetic 1-5 g/day
Antihistaminic 2 g/day orl man
Antihypertensive
Antiinfertility 1 g/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiinflammatory Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilepric 1.5 g/man/dayMartindale's 28th
Antilithic 1,000-3,000 mg/day
Antimaculitic
Antimeasles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antimenopausal 500-5,000 mg/day
Antimigraine Martindale's 29th
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antineuramidase
Antinitrosic 1 g/man/dayMartindale's 28th
Antiobesity 1 g 3x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiorchitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiosteoarthritic 1 g 2x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antiosteoporotic 500 mg/day
Antioxidant 100 ppm
Antiparkinsonian 1 g 2-3x/day
Antiparotitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antiperiodontitic 1 g 2x/dayWerbach, M. 1993. Healing with Food. Harper Collins, New York, 443 pp.
Antipneumonic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipodriac Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antipoliomyelitic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antipyretic Economic & Medicinal Plant Research, 6: 189.
Antiradicular Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antiretinotic
Antirheumatic
Antirhinitic 1,000 mg 3x/day
Antiscorbutic 10 mg/man/dayMartindale's 28th
Antiseptic MIC=3.3-217 mg/mlMartindale's 28th
Antiseptic 4-8 g/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antishingles Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Antispasmodic 500-5,000 mg/day
Antistress 500-1,000 mg
Antisyndrome-X 1-4 g/dayChallem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Antitumor (Gastric)
Antitumor (Lung)
Antiulcer
Antiviral 1-5 g/day
Apoptotic 1-10 mM
Asthma-preventive 1,000 mg/day/orlPizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Beta-Adrenergic Receptor Blocker
Beta-Glucuronidase-Inhibitor 1.5 g/day/man
Calcium-Antagonist
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective
Cold-preventive 1-2 g/dayDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Collagenic
Detoxicant
Diuretic 700 mg/man/orl
Fistula-Preventive Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Hypocholesterolemic 300-1,000 mg/dayDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Hypoglycemic Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Hypotensive 1,000 mg/man/day
Immunomodulator
Immunostimulant Challem, J., Berkson, Burt, and Smith, Melissa Dianne. 2000. Syndrome X - The complete nutritional program to prevent and reservse insulin resistance. John Wiley & Sons, New York. 272 pp. $24.95
Interferonogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Lithogenic Davies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Mucolytic 1 g/woman/dayMartindale's 28th
Pesticide
Uricosuric 4 g/man/dayDavies, S., and Stewart, A. 1990. Nutritional Medicine. Avon Books, New York. 509pp.
Urinary-Acidulant Martindale's 29th
Vasodilator
Vulnerary Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
GALACTOSE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (1)
Sweetener 0.32 x sucroseMartindale's 28th
APIGENIN-7-MONOGLUCOSIDE Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
URSOLIC-ACID Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (89)
Analgesic
AntiEBV Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
AntiHIV EC50=2.0 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC85=18 ug/ml
AntiHIV 6.7 uM
AntiTGF-beta IC50=6-7.5 uM
Antialzheimeran Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Antiarrhythmic
Antiarthritic Planta Medica, 57: A56, 1991.
Antibacterial
Anticancer Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticancer (Colon) Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticholestatic 28-100 mg/kg orlShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Anticomplement IC100 0.1 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antidiabetic Chemical Constituents of Oriental Herbs (3 diff. books)
Antiedemic
Antiescherichic
Antifibrosarcomic IC80=10 uM
Antihepatotoxic 5-20 mg/kg iprShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antihistaminic Tsuruga, T., Chun, Y.-T., Ebizuka, Y., and Sankawa, U. 1991. Biologically Active Constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells. Chem. Pharm. Bull. 39(12): 3276-3278, 1991.
Antihyperlipidemic
Antiinflammatory 1/3 indomethacin
Antiinflammatory IC24=500 mg/kg
Antileishmanic ED50=20 uM
Antileukemic IC50=2.5-17.8 ug/ml
Antilymphomic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antimalarial IC50=28-37 ug/ml
Antimetastatic IC80=10 uM
Antimutagenic IC57-80=80 mg/kg
Antinephritic IC50=6-7.5 uM
Antiobesity? Internat. J. Oriental Med. 16: 4.
Antioxidant IC50=10 uM
Antiperoxidant IC35=200 ug/ml
Antiplasmodial IC50=28-37 ug/ml
Antiproliferative IC50=15-20 uM
Antistaphylococcic
Antithromboxane IC50=50 uM
Antitrypanosomic
Antitumor Cancer Research, 54: 701, 1994.
Antitumor (Breast) 0.5% diet
Antitumor (Breast) IC50=15-20 uM
Antitumor (Cervix) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Stomach) IC50=15-20 uM
Antitumor (brain) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor-Promoter Planta Medica, 57: A56, 1991.
Antiulcer Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antiviral IC85=18 ug/ml
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
CNS-Depressant
COX-2-Inhibitor IC50=130 uM/
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Cardioprotective
Cardiotonic
Choleretic 5-20 mg/kg orlShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Cyclooxygenase-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic 50 ppm
Cytotoxic ED50=3.75 ug/ml
Cytotoxic 7.2 uM
Diuretic
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective 1-100 ug/ml
Hepatoprotective 10 mg/kg
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive
Immunomodulator
Leucocytogenic
Lipoxygenase-Inhibitor IC50=0.18 mM
MMP-9-Inhibitor IC80=10 uM
Ornithine-Decarboxylase-Inhibitor
Pesticide
Piscicide
Potassium-Sparing 3 mg/ratIwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Protease-Inhibitor IC85=18 ug/ml
Protisticide Chemical Express, 7: 285, 1992.
Quinone-Reductase-Inducer 5 ug/mlLee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
Sodium-Sparing 3 mg/ratIwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
TOPO-2-Inhibitor
Trypanocide
Vasopressor
FERULIC-ACID Plant-- -- Jim Duke's personal files.
Activities (61)
Allelopathic Holappa, L.D., and Blum*, U. 1991. Effects of Exogenously Applied Ferulic Acid, a Potential Allelopathic Compound, on Leaf Growth, Water Utilization, and Endogenous Abscisic Acid Levels of Tomato, Cucumber, and Bean. J. of Chemical Ecology, 17(5): 865.
Analgesic Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 69.
Antiaggregant Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Antiallergic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiarrhythmic
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticancer (Colon)
Anticancer (Forestomach)
Anticancer (Liver)
Anticancer (Skin)
Anticarcinogenic
Antidysmenorrheic
Antiestrogenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiherpetic
Antiinflammatory Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Antileukemic IC50=25-56 ug/mlChiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antineoplastic (Stomach)
Antinitrosaminic Ki Soon Rhee. Oilseed Food Ingredients Used To Minimize Oxidative Flavor Deterioration in Meat Products. Phenolic Compounds in Food and Their Effects on Health, Ch.18.
Antioxidant 3,000 uM
Antioxidant IC51=200 ppm
Antioxidant 1/3 quercetin
Antioxidant 1/2 BHA
Antioxidant EC50=9-15 ug/ml
Antiradicular EC50=9-15 ug/ml
Antiradicular IC50=116-124 uM
Antiserotonin Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antithrombic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antitumor (Colon)
Antitumor (Forestomach)
Antitumor (Liver)
Antitumor (Skin)
Antitumor-Promoter IC46=10 uMCancer Research, 48: 5941.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Arteriodilator Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cardiac Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cholagogue Pharmazie, 46: 156, 1991.
Choleretic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Fungicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Hepatoprotective Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Hepatotropic
Herbicide Angewandte Botanik 68(5/6)=1994. Page 195.
Hydrocholerectic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hypolipidemic
Immunostimulant Economic & Medicinal Plant Research, 1: 124.
Insectifuge Tunon, H., Thorsell, W., and Bohlin, L. 1993. Mosquito Repelling Activity of Compounds Occurring in Achillea millefolium L. (Asteraceae). Economic Botany 48(2): 111-120, 1994.
Metal-Chelator McEvily, A.J., Iyengar, R., and Gross, A.T. Inhibition of Polyphenol Oxidase by Phenolic Compounds. Phenolic Compounds in Food and Their Effects on Health, Ch.25.
Ornithine-Decarboxylase-Inhibitor Hagerman, A.E. Tannin-Protein Interactions. Phenolic Compounds in Food and Their Effects on Health, Ch.19.
Pesticide
Phagocytotic
Preservative Merck 11th Edition
Prostaglandigenic
Prostaglandin-Synthesis-Inhibitor 0.58-3.2 mMXu, L. N., Yu, W. G., Tian, J. Y., Liu, Q. Y. 1990. Effect of Sodium Ferulate on Arachidonic Acid Metabolism. Yao Hsueh Hsueh Pao, 25(6): 412-416.
Sunscreen Chemical Marketing Reporter; a weekly tabloid, 9/10/92.
Uterosedative 30-100 mg/kg ivn ratOzaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
SINAPIC-ACID Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (9)
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antihepatotoxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant IC27=30 ppm
Antiperoxynitrite IC39=5 uM
Antiperoxynitrite IC60=20 uM
Antiperoxynitrite IC75=100 uM
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
ROSMARINIC-ACID Root-- -- Jim Duke's personal files.
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
ELLAGIC-ACID Plant-- -- List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (51)
ACE-Inhibitor IC50=5 mM/l
Abortifacient 1.2 mg/kg ivn mus
Aldose-Reductase-Inhibitor IC50=0.2 uM
Aldose-Reductase-Inhibitor IC50=0.2 ug/ml (strong activity)
AntiGTF ID50=20 ug/ml
AntiHIV IC90=200 ug/mlTan, G.T., Pezzuto, J.M., Kinghorn,* A.D., Hughes, S.H. Evaluation Of Natural Products As Inhibitors Of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. Journal of Natural Products, 54(1): 143-154, 1991.
Antiaflatoxin
Antianaphylactic
Antibacterial 1,250 ug/ml
Antibacterial ID50=20 ug/ml
Anticancer (Cervix) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Colon) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Esophagus) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticancer (Mouth) Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic ID50=20 ug/ml
Anticataract Shimizu, M., Horie, S., Terashima, S., Ueno, H., et al. 1989. Studies on Aldose Reductase Inhibitors from Natural Products.II. Active Components of a Paraguayan Crude Drug 'Para-parai mi,' Phyllanthus niruri. Chem. Pharm. Bull. 37(9): 2531-2532, 1989.
Antigingivitic 1,250 ug/ml
Antihyperthyroid
Antiinflammatory
Antimalarial IC50=0.5 uMRukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antimutagenic
Antioxidant >50 x tocopherolOsawa, T. Phenolic Antioxidants in Dietary Plants as Antimutagens.Phenolic Compounds in Food and Their Effects on Health, Ch.11 p.142.
Antioxidant IC98=30 ppm
Antioxidant 2/3 quercetin
Antiperiodontic 1,250 ug/ml
Antiperoxidant IC50=29 uMPlanta Medica, 57: A54, 1991.
Antiplaque 1,250 ug/ml
Antiplasmodial IC50=0.5 uMRukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
Antiseptic 1,250 ug/ml
Antistreptococcic ID50=20 ug/ml
Antithyroid Jim Duke's personal files.
Antitumor
Antiviral Economic & Medicinal Plant Research, 5: 224.
Antiyeast IC50=10.5 uM
Apoptotic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Astringent Martindale's 29th
Cancer-Preventive 3 ppm
Candida-SAP-Inhibitor IC50=8.4 uM
Cytotoxic 4.6 ug/mlAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 359.
Deiodinase-Inhibitor Jim Duke's personal files.
Detoxicant
Glucosyl-Transferase-Inhibitor ID50=20 ug/ml
HIV-RT-Inhibitor Economic & Medicinal Plant Research, 5: 224.
Hemostatic Merck 11th Edition
Hepatoprotective IC55=30 ug/mlMayumi Ito (nee Someya), et al. 1990. Hepatoprotective Compounds from Canarium album and Euphorbia nematocypha. Chem. Pharm. Bull. 38(8): 2201-2203, 1990.
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Quinone-Reductase-Inducer 0.4 g/kg ratAhn, D., Putt, D., Kresty, L., Stoner, G. D., Fromm, D., Hollenberg, P. F. 1996. The Effects of Dietary Ellagic Acid on Rat Hepatic and Esophageal Mucosal Cytochromes P450 and Phase II Enzymes. Carcinogenesis, 17(4): 821-828.
Sunscreen 0.50%Jim Duke's personal files.
Topoisomerase-I-Antagonist Journal of Medicinal Food 2: 167.1999.
Xanthine-Oxidase-Inhibitor IC50=3.1 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.