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Activities: 161
All Chemicals: 27
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Chemical Low PPM High PPM StdDev *Reference
3-EPIOLEANOLIC-ACID Resin, Exudate, Sap-- -- *
ALPHA-SITOSTEROL Resin, Exudate, Sap-- -- *
ALPHA-STORESIN Resin, Exudate, Sap-- -- *
BENZYL-ALCOHOL Resin, Exudate, Sap-- -- *
Activities (9)
Allergenic Martindale's 29th
Anesthetic Martindale's 28th
Antiodontalgic Martindale's 28th
Antipruritic
Antiseptic Martindale's 29th
FLavor Fema 200-1,200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Pesticide
Sedative Jim Duke's personal files.
BENZYL-CINNAMATE Resin, Exudate, Sap-- -- *
Activities (4)
Allergenic
FLavor FEMA 1-125Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery
BETA-SITOSTEROL Resin, Exudate, Sap-- -- *
Activities (47)
Androgenic
Angiogenic
Anorexic Martindale's 28th
Antiadenomic Merck 11th Edition
Antiandrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antibacterial Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Anticancer (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Anticancer (Cervix)
Anticancer (Lung)
Antiedemic IC54=320 mg/kg orl
Antiestrogenic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antifertility Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antigonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antihyperlipoproteinaemic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory
Antileukemic
Antilymphomic
Antimutagenic 250 ug/ml
Antiophidic 2.3 mg musEconomic & Medicinal Plant Research, 5: 363.
Antioxidant IC44=10 uM
Antiprogestational Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Antiprostaglandin 30 mg/day/12 wks
Antiprostatadenomic Merck 11th Edition
Antiprostatitic 10-20 mg 3 x/day/orl man
Antipyretic Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antitumor (Breast) Madhavi, D. L., Bomser, J., Smith, M., Singletary, K. 1998. Isolation of Bioactive Constituents from Vaccinium myrtillus (Bilberry) Fruits and Cell Cultures. Plant Sci., 131(1): 95-103.
Antitumor (Cervix)
Antitumor (Lung)
Antiviral Abid Ali Khan, M.M., Jain, D.C., Bhakuni, R.S., Zaim, M., and Thakur, R.S. 1991. Occurrence of some antiviral sterols in Artemisia annua. Plant Science, 75: 161-165, 1991.
Apoptotic
Artemicide LC50=110 ppmJung, J.H., Pummangura, S., Chaichantipyuth, c., Patarapanich, C., and McLaughlin, J.L. 1989. Bioactive Constituents of Melodorum fruticosum. Phytochemistry. 29(5): 1667-1670. 1990.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Recently became Internat. J. Crude Drug Res. 28(1,2,3,4):1990, page 155.
Caspase-8-Inducer
Estrogenic
Febrifuge Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Gonadotrophic Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Hepatoprotective
Hypocholesterolemic 2-6 g/man/day/orlMartindale's 30th
Hypocholesterolemic 9-3,330 mg/man/day/orlMartindale's 28th
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypolipidemic 2-6 g/day
Pesticide
Spermicide Malini, T. and Vanithakumari, G. 1989. Rat Toxicity Studies With B-Sitosterol. Journal of Ethnopharmacology, 28: 221-234, 1990.
Ubiquiot Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Ulcerogenic 500 mg/kg ipr rat
BETA-STORESIN Resin, Exudate, Sap-- -- *
CINNAMIC-ACID Resin, Exudate, Sap20000.0 150000.0 -1.0 *
Activities (18)
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity)Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Allergenic
Anesthetic
Antibacterial Martindale's 28th
Antiinflammatory
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antispasmodic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Choleretic
Dermatitigenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 4-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Herbicide
Laxative
Lipoxygenase-Inhibitor
Pesticide
Tyrosinase-Inhibitor ID50=700 uM
Vermifuge
CINNAMIC-ALCOHOL Resin, Exudate, Sap-- -- *
Activities (3)
Allergenic
FEMA 3-700Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
CINNAMYL-CINNAMATE Resin, Exudate, Sap50000.0 100000.0 1.0 *
Activities (1)
FLavor FEMA <1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
EO Resin, Exudate, Sap5000.0 10000.0 -1.6 *
ETHANOL Resin, Exudate, Sap-- -- *
Activities (24)
Allergenic
Anesthetic 4,000 orl catBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Anesthetic 6,000 orl ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Anhydrotic Martindale's 29th
Antiatherosclerotic
Antibacterial Martindale's 28th
Antipruritic Martindale's 28th
Antiseptic Merck 11th Edition
CNS-Depressant Martindale's 28th
Expectorant Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp.
Hepatotoxic Martindale's 29th
Hypertensive >1 drink/day
Hypnotic Antidote=NaloxoneMartindale's 29th
Hypocalcemic 4,000 orl ratBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Hypotensive 1 drink/day
Mucotropic Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp.
Neurolytic Merck 11th Edition
Pesticide
Rubefacient Martindale's 29th
Sclerosant Martindale's 29th
Surfactant Schulz, V, Hansel, R and Tyler, VE. 1998. Rational Phytotherapy - A Physician's Guide to Herbal Medicine. 3rd ed. 1st English Edition. Translated by Terry C. Telger. Springer Verlag, Heidelberg. 306 pp.
Teratogenic 6,000 orl dogBorchard, R. E., Barnes, C. D., and Eltherton, L. G. 1991. Drug Dosage in Laboratory Animals: A Handbook. (3rd Ed.) The Telford Press, Inc., P. O. Box 287, Caldwell NJ 07006.
Tremorilytic Martindale's 28th
Ulcerogenic 5 ml/kg (50%) orl rat
ETHYL-CINNAMATE Resin, Exudate, Sap-- -- *
Activities (2)
FLavor FEMA 4-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Nematicide MLC=1,000 uMShoyakugaku Zasshi, 44: 183.
MONOTROPEOSIDE Plant-- -- *
OLEANOLIC-ACID Resin, Exudate, Sap-- -- *
Activities (64)
Abortifacient
AntiHIV IC50=21.8 ug/ml
AntiHIV EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiPGE2 IC50=24 uM
AntiTGF-beta IC50=19-24 uM
Antiallergic
Antiarrhythmic 40 mg/kg
Antiatherosclerotic
Antibacterial MIC=625-1,250 ug/ml
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplement IC40-50 0.01 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiedemic IC36=40 mg/kg ipr rat
Antifertility
Antigingivitic MIC=625-1,250 ug/ml
Antihepatotoxic
Antihyperlipidemic
Antiinflammatory 40 mg/kg iprAquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.
Antiischemic 40 mg/kg
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene IC50=17 uM
Antimalarial IC50=70-89 ug/ml
Antinephritic IC50=19-24 uM
Antioxidant Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.
Antioxidant IC46=10 uM
Antiperiodontic MIC=625-1,250 ug/ml
Antiperoxidant IC30=200 ug/ml
Antiplaque MIC=625-1,250 ug/ml
Antiplasmodial IC50=70-89 ug/ml
Antisarcomic
Antiseptic MIC=625-1,250 ug/ml
Antitumor
Antitumor (Breast) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiulcer >carbenoxolone
Antiviral EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiviral IC50=21.8 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
COX-2-Inhibitor IC50=295 uM/
COX-2-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective 40 mg/kg
Cardiotonic
Cyclooxygenase-Inhibitor
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.
Hypolipemic
Hypotensive
Immunomodulator
Leucocytogenic
NF-kB-Inhibitor
Phagocytotic
Piscicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Prostaglandin-Synthesis-Inhibitor igs mus
Sedative
Uterotonic
Vasopressor
PHENYLETHYLENE Resin, Exudate, Sap-- -- *
PHENYLPROPYL-ALCOHOL Resin, Exudate, Sap-- -- *
PHENYLPROPYL-CINNAMATE Resin, Exudate, Sap-- 100000.0 *
SHIKIMIC-ACID Plant-- -- *
Activities (14)
Analgesic
Anticancer
Anticonvulsant Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Antioxidant 7 x quercetin
Antiradicular 7 x quercetin
Antispasmodic Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
Antitumor
Antitumor-Promoter
Bruchifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Cancer-Preventive
Carcinogenic Merck 11th Edition
Ileorelaxant
Mutagenic
Pesticide
STORESIN Resin, Exudate, Sap330000.0 500000.0 *
STORESIN-CINNAMATE Resin, Exudate, Sap-- -- *
STYRACIN Resin, Exudate, Sap50000.0 100000.0 *
STYRENE Essential Oil-- -- *
Activities (3)
Irritant
Narcotic Merck 11th Edition
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
STYROL Resin, Exudate, Sap-- -- *
TANNIN Plant-- -- *
Activities (35)
Anthelmintic
AntiHIV
Antibacterial
Anticancer
Anticariogenic
Antidiarrheic
Antidysenteric
Antihepatotoxic
Antihypertensive
Antilipolytic
Antimutagenic
Antinephritic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiophidic Economic & Medicinal Plant Research, 5: 363.
Antioxidant IC50=1.44 ug/ml
Antioxidant 1/3 quercetin
Antiradicular 500 mg/kg/day orl musUchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antiradicular 1/3 quercetin
Antirenitic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Antitumor
Antitumor-Promoter
Antiulcer
Antiviral
Cancer-Preventive HerbalGram No. 22 - Spring 1990, page 14.
Carcinogenic
Chelator
Cyclooxygenase-Inhibitor
Glucosyl-Transferase-Inhibitor
Hepatoprotective
Immunosuppressant
Lipoxygenase-Inhibitor
MAO-Inhibitor
Ornithine-Decarboxylase-Inhibitor
Pesticide
Psychotropic Uchida, U., Ohta, H., Niwa, M., Mori, A., Nonaka, G-i., Nishioka, I., and Zaki, M. 1989. Prolongation of Life Span of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) Ingesting Persimmon Tannin. Chem. Pharm. Bull. 38(4): 1049-1052, 1990.
Xanthine-Oxidase-Inhibitor
VANILLIN Resin, Exudate, Sap-- -- *
Activities (28)
Allelochemic IC50=4.26 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic
Antianemic
Anticancer
Antidrepanocytic
Antiescherichic 10-100 mmol/l
Antilactobacillic 10-100 mmol/l
Antilisteria
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antioxidant #NAME?
Antipolio Economic & Medicinal Plant Research, 5: 194.
Antiradicular 7 x quercetin
Antisickling
Antitumor
Antitumor-Promoter
Antiviral Economic & Medicinal Plant Research, 5: 194.
Antiyeast 8-30 mM
Bacteristat 10-40 mmol/l
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide 8-20 mM
Choleretic Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
FLavor FEMA 50-20,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Immunosuppressant
Insectifuge? Martindale's 28th
Irritant
Perfumery
Pesticide
WATER Resin, Exudate, Sap150000.0 300000.0 0.8 *
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.