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Activities: 340
Chemicals w/Activities: 45
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Chemical Low PPM High PPM StdDev *Reference
1,8-CINEOLE Plant1000.0 3434.0 0.4 Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Activities (67)
(-)-Chronotropic 87 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 87 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Acaricide LC100=6 uM
Allelopathic
Allergenic
Anesthetic
Anthelmintic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiacetylcholinesterase IC50=41 ug/ml
Antiallergic J. Food Hyg. Soc. Jap. 33(6): 569.
Antibacterial 50 ppm
Antibronchitic
Anticariogenic
Anticatarrh Martindale's 29th
Anticholinesterase IC50=50-70
Antifatigue
Antihalitosic American Health, 12(4): 17, 1993.
Antiinflammatory
Antilaryngitic
Antinociceptive
Antipharyngitic
Antiplaque
Antirheumatic
Antirhinitic
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antisinusitic
Antispasmodic
Antistaphylococcic 50 ppm
Antitussive
Antiulcer
CNS-Stimulant
Candidicide
Carcinogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Choleretic
Convulsant
Counterirritant Martindale's 29th
Cytochrome-P450-Inducer
Decongestant
Degranulant 0.3 ul/ml
Dentifrice Martindale's 29th
Edemagenic inj
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 1-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective
Gram(+)icide
Gram(-)icide
Hepatotonic
Herbicide IC50=78 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypotensive
Inflammatory inj
Insectifuge
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Neurotoxic
P450-Inducer
Pediculicide 2.3 x pyrethrin
Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Rubefacient Martindale's 29th
Secretogogue
Sedative
Spasmogenic
Surfactant
Testosterone-Hydroxylase-Inducer
Transdermal
Trichomonicide LD100=1,000 ug/ml
3-OCTANOL Plant-- -- Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (2)
FLavor FEMAAloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
ALPHA-BISABOLOL Plant4.0 10.0 -1.19 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (20)
Analgesic Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
Antiarthritic Lawrence Review of Natural Products, Mar-91.
Antibacterial Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiburn Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Antiinflammatory
Antipeptic Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antipyretic Lawrence Review of Natural Products, Mar-91.
Antiseptic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Antispasmodic
Antituberculic
Antiulcer Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Candidicide
Cicatrizant ED50=228 ug/g mus
Cosmetic Fitoterapia No.61: 254, 1990.
Fungicide Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Musculotropic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Protisticide
Vulnerary ED50=228 ug/g mus
ALPHA-CADINOL Plant1.0 21.0 -0.53 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (3)
Acaricide
Antimite
Pesticide
ALPHA-HUMULENE Plant-- 51.0 -0.28 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (2)
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ALPHA-PHELLANDRENE Plant2.0 13.0 -1.08 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (11)
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Dermal Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Emetic
FLavor FEMA 10-130Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Insectiphile Pakistan Encyclopedia Planta Medica. 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Laxative
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
ALPHA-PINENE Plant90.0 748.0 0.05 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (28)
Allelochemic
Allergenic
Antiacne
Antibacterial
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory 500 mg/kg
Antipneumonic
Antiseptic
Antispasmodic
Antistaphylococcic
Antiviral Economic & Medicinal Plant Research, 5: 195.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Coleoptophile
Expectorant Michael Castleman 1991. The Healing Herbs. Rodale Press, Emmaus, PA 436 pp.
FLavor FEMA 15-150Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide IC50=30 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insecticide 0.82 uM/fly
Insectifuge 50 ppm
Insectiphile J. Stored. Prod. Res., 22:141, 1986.
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
P450-2B1-Inhibitor IC50=0.087 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Sedative Lawrence Review of Natural Products, Jun-90.
Spasmogenic
Tranquilizer Lawrence Review of Natural Products, Jun-90.
Transdermal
ALPHA-TERPINENE Plant4.0 11.0 -0.49 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (13)
ACE-Inhibitor 100 ug/ml (weak activity)
Acaricide
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Antiacetylcholinesterase IC50=1.0 mM
Antinitrosaminic
Antispasmodic
FLavor FEMA 1-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 0.86 uM/fly
Insectifuge
P450-2B1-Inhibitor IC50=0.76 uM
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic
ALPHA-TERPINEOL Plant35.0 209.0 -0.32 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (23)
ACE-Inhibitor 100 ug/ml (weak activity)
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacne
Antibacterial MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Anticancer Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Anticariogenic MIC=800-1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antiinflammatory
Antiproliferant
Antiseptic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Cicatrizant ED50=240 ug/g mus
FLavor FEMA 5-40Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insecticide 1.29 uM/fly
Interleukin-6-Inhibitor
Mosquitofuge > Deet
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Termiticide IC100=5 mg/g
Transdermal
Vulnerary ED50=240 ug/g mus
ALPHA-THUJONE Plant2.0 9.0 -1.42 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (6)
Abortifacient Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial J. Ess. Oil Res. 7: 271.
Emmenagogue Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Insecticide
Larvicide Misra, L.N. and Singh, S.P. Alpha-Thujone, The Major Component Of The Essential Oil From Artemisia vulgaris Growing Wild In Nilgiri Hills. Journal of Natural Products, 49: 941, 1986.
Pesticide
BETA-BISABOLENE Plant1.0 15.0 -0.6 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (6)
Abortifacient
Antirhinoviral IC50=1,800?Denyer, C.V., Jackson, P., Loakes, D.M., Ellis, M.R., and Yound, D.A.B. Isolation of Antirhinoviral Sesquiterpenes From Ginger (Zingiber officinale). Journal of Natural Products, 57(5): 658-662, 1994.
Antiulcer IC57=100 mg/kgYamahara, J., et al. Stomachic principles in ginger. II. Pungent and anti-ulcer effects of low polar constituents isolated from ginger, the dried rhizoma of... Yakugaku Zasshi 112: 645-655 (1992).
Antiviral IC50=1,800?Denyer, C.V., Jackson, P., Loakes, D.M., Ellis, M.R., and Yound, D.A.B. Isolation of Antirhinoviral Sesquiterpenes From Ginger (Zingiber officinale). Journal of Natural Products, 57(5): 658-662, 1994.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Stomachic
BETA-PINENE Plant60.0 374.0 -0.03 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (13)
Allergenic
Antiinflammatory
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic
Candidicide
FLavor FEMA 15-600Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Herbicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Spasmogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Transdermal
BETA-THUJONE Plant4.0 20.0 -0.88 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (5)
Abortifacient Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial J. Ess. Oil Res. 7: 271.
Emmenagogue Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Insectifuge
Pesticide
BORNEOL Plant20.0 759.0 0.01 *
Activities (35)
(-)-Chronotropic 29 ug/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 29 ug/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Allelochemic
Analgesic
Antiacetylcholine Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antibacterial MIC=125-250 ug/ml
Antibronchitic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiescherichic MIC=125 ug/ml
Antifeedant
Antiinflammatory
Antiotitic
Antipyretic
Antisalmonella MIC=125 ug/ml
Antispasmodic ED50=0.008 mg/ml
Antistaphylococcic MIC=250 ug/ml
Antiyeast MIC=250 ug/ml
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
CNS-Toxic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Candidicide MIC=250 ug/ml
Choleretic
FLavor FEMA<1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective
Herbicide IC50=470 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=470 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Inhalant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insect-Repellent
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Medline (post 1990 searches filed in my computer)
Tranquilizer
BORNYL-ACETATE Plant1.0 76.0 -0.42 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (12)
(-)-Chronotropic 933 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
(-)-Inotropic 933 nl/mlHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antibacterial Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antispasmodic ED50=0.09 mg/mlFitoterapia No.59-1984.
Antiviral Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 70-80Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
Sedative
CAMPHENE Plant25.0 231.0 -0.21 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (9)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antilithic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antioxidant Jim Duke's personal files.
Expectorant Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
FLavor FEMA 15-175Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Hypocholesterolemic? Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Pesticide
Spasmogenic Fitoterapia No.59-1984.
CAMPHOR Plant480.0 3300.0 1.02 *
Activities (41)
Allelopathic
Analgesic
Anesthetic
Antiacne Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Antidiarrheic 500 ug/mlWealth of India.
Antidysenteric 500 ug/mlWealth of India.
Antiemetic 100-200 mg man orlHuang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antifeedant IC50=5,000 ppm dietLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrositic Martindale's 28th
Antineuralgic Martindale's 28th
Antipruritic Merck 11th Edition
Antiseptic Merck 11th Edition
Antispasmodic ED50=0.075 mg/mlFitoterapia No.59-1984.
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Convulsant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Cosmetic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Counterirritant Martindale's 28th
Decongestant Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Deliriant Merck 11th Edition
Ecbolic
Emetic
Epileptigenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Expectorant Martindale's 29th
Fungicide ED50=2.7 mMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Herbicide IC50=3.3-180 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Insect-Repellent
Insectifuge
Irritant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Occuloirritant
P450-2B1-Inhibitor IC50=7.89 uM
Pesticide
Respirainhibitor Merck 11th Edition
Respirastimulant Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Rubefacient
Stimulant R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Transdermal
Verrucolytic Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Vibriocide 500 ug/mlWealth of India.
CARVONE Plant12.0 5.0 -0.43 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (19)
Allergenic
Antiacetylcholinesterase IC50=1.4-1.8 mM
Antiproliferative
Antiseptic 1.5 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
CNS-Stimulant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
FLavor FEMA 80-3,000Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungistat
Insecticide Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Trichomonicide LD100=300 ug/ml
Vermicide
CARYOPHYLLENE Plant-- 191.0 -0.32 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (31)
Aldose-Reductase-Inhibitor
Allergenic
Analgesic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiacne
Antiasthmatic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial
Anticariogenic MIC=>1,600 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antidermatitic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant 500 ppmKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Antiinflammatory IC50=100 uMShimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antileishmanic
Antionychyotic Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Antiproliferant
Antispasmodic
Antistaphylococcic
Antistreptococcic
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Candidicide
FLavor FEMA 20-200Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Gastroprotective Taylor, Leslie. 2005. The Healing Power of Rainforest Herbs. SquareOne Publisher, Garden City Park, NY. 519 pp.
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide
Mosquitocide
Perfumery Merck 11th Edition
Pesticide
Sedative
Termitifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CARYOPHYLLENE-OXIDE Plant6.0 24.0 -0.37 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (8)
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antifeedant Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Calcium-Antagonist ED50=32 uM gpg
Fungicide
Insecticide Bettarini, F., Borgonovi, G.E., et al. 1991. Antiparasitic Compounds from East African Plants: Isolation and Biological Activity of Anonaine, Matricarianol, Canthin-6-One and Caryophyllene Oxide. Insect Sci. Applic. 14(1): 93-99, 1993.
Pesticide
CIS-OCIMENE Plant-- 55.0 -0.32 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (3)
Antibacterial Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Fungicide Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
CITRONELLAL Plant1.0 7.0 -1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (20)
Acaricide
Allergenic
Antibacterial
Antiseptic 3.8 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antistaphylococcic
Antistreptococcic
Candidicide
Embryotoxic
FLavor FEMA <1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insectifuge Merck 11th Edition
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Mutagenic?
Nematicide MIC 1 mg/mlShoyakugaku Zasshi, 44: 183.
P450-2B1-Inhibitor IC50=1.56 uM
Perfumery
Pesticide
Sedative ED=1 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Teratogenic
CITRONELLOL Plant1.0 41.0 -0.65 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (15)
Allergenic
Antibacterial
Antiseptic
Antistaphylococcic
Antistreptococcic
Candidicide
FLavor FEMA 1-50Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide HerbalGram No. 17.
Herbicide IC50=160 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Nematicide MLC=100 ug/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Sedative Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Trichomonicide LD100=300 ug/ml
COUMARIN Plant-- 22.0 -0.67 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (57)
Aldose-Reductase-Inhibitor 10 ug/ml cow (weak activity, 11% inhibition)Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Allelochemic IC100=2 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Analgesic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Anesthetic
Antiaggregant
Antiandrogenic Planta Medica, 56(6): 671, 1990.
Antibrucellosic Gawron, A., Gorski*, G., Glowniak**, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990.
Anticancer (Kidney) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Anticancer (Prostate) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antidiuretic
Antiedemic Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antiesherichic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiinflammatory Shimizu,*M., et al. 1990. Anti-inflammatory Constituents of Topically Applied Crude Drugs. IV.1) Constituents and Anti-inflammatory Effect of Paraguayan Crude Drug 'Alhucema' (Lavandula latifolia Vill.)2). Chem. Pharm. Bull. 38(8): 2283-2284, 1990.
Antilymphedemic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimelanomic 50 mg/day
Antimetastatic 50 mg/man/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimitotic Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7.
Antimononuccleotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antimycoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antipsittacotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antipsoriac Pandeya, S.N. 1970. Biological Activity of Adamantyl Derivatives. The Indian Journal of Pharmacy, 33: 7.
Antitoxoplasmotic Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antitumor 50 mg/day
Antitumor (GI)
Antitumor (Kidney) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Antitumor (Prostate) 400-7,000 mg/dayMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Bacteristat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Bruchiphobe
Cancer-Preventive 5-25 ug/mlGawron, A. and Glowniak, K. 1987. Cytostatic Activity of Coumarins in vitro. Planta Medica 1987: 526.
Carcinogenic 200 mg/kg orl musMills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
Cardiodepressant
Cardiotonic
Chemopreventive
DME-Inhibitor IC50=57.5 uMAdvance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 134.
Emetic
Estrogenic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Fungicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hemorrhagic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Hepatotoxic 0.8-1.71 mM/kg orl rat
Hepatotoxic 2,500 ppm diet
Hepatotoxic 100 mg/kg dog
Hypnotic Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
Hypoglycemic 250-1,000 mg/kg orlEconomic & Medicinal Plant Research, 6: 165
Immunostimulant
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lymphocytogenic 100 mg/dayGawron, A., Gorski*, G., Glowniak**, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990.
Lymphokinetic
Narcotic
Ovicide
Pesticide
Phagocytotic Planta Medica, 56(6): 671, 1990.
Piscicide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Respirodepressant
Rodenticide Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sedative Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
CUMINALDEHYDE Plant3.0 42.0 -1.0 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (10)
Antibacterial
FLavor FEMA <1Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Singh*, G., Upadhyay, R.K. 1990. Fungitoxic Activity of Cumaldehyde, Main Constituent of the Cuminum cyminum Oil. Fitoterapia 62(1): 86, 1991.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Larvicide Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Tyrosinase-Inhibitor ID50=0.05 mM
Ulcerogenic Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
EUGENOL Plant-- 9.0 -0.61 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (76)
Acaricide LD50=5.47 ug/sq cm cf DEET at 37.59 ug/sq cm
Allergenic
Analgesic Merck 11th Edition
Anesthetic 200-400Phytotherapy Research, 4: 93.
AntiTNF
Antiaggregant IC50=0.3 uMPhytotherapy Research, 4: 93.
Antiarachidonate
Antibacterial 500 ppmValnet, J. 1982. The Practice of Aromatherapy. Translated from the 1980 French Edition by Robin Campbell and Libby Houston. Destiny Books, New York. 279 pp.
Antibacterial MBC=400 ug/ml
Anticonvulsant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiedemic 100Phytotherapy Research, 4: 95.
Antiestrogenic
Antifeedant Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Antigenotoxic 50-500 mg/kg orl mus
Antiherpetic IC50=16.2-25.6 ug/ml
Antiinflammatory (11 uM) IC~97=1,000 uM
Antikeratotic IC50=16.2-25.6 ug/ml
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antinitrosating
Antioxidant IC65=30 ppm
Antioxidant 10 uM
Antiprostaglandin 11 uM
Antiprostaglandin IC50=9.2 mM
Antipyretic 3 ml/man/day
Antiradicular EC50=2 ul/l
Antisalmonella MIC=400 ug/ml
Antiseptic 3 ml/man/day
Antiseptic 400 ug/ml
Antispasmodic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antistaphylococcic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antithromboxane Lawrence Review of Natural Products, Jul-87.
Antitumor Zheng, G-Q., Kenney, P.M., and Lam, L.K.T. Sesquiterpenes From Clove (Eugenia caryophyllata) As Potential Anticarcinogenic Agents. Journal of Natural Products 55(7): 999-1003, 1992.
Antiulcer
Antiviral IC50=16.2-25.6 ug/ml
Apifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
CNS-Depressant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
COX-1-Inhibitor IC97=1,000 uM
COX-2-Inhibitor IC>97=1,000 uM
COX-2-Inhibitor IC50=129 uM
Calcium-Antagonist IC50=224 uM
Calcium-Antagonist IC50=200 uM gpg
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide Phytotherapy Research, 4: 93.
Carcinogenic? Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Carminative Yamamoto, A., Umemori, S., and Muranishi, S. 1993. Absorption Enhancement of Intrapulmonary Administered Insulin by Various Absorption Enhancers and Protease Inhibitors in Rats. J. Pharm. Pharmacol. 46: 14-18, 1994.
Choleretic
Cytochrome-P450-Inhibitor Pizzorno, J. 1998. Total Wellness. Prima Health, a division of Prima.
Cytotoxic 25 ug/mlPhytotherapy Research, 4: 93.
Dermatitigenic
Enterorelaxant J. Aromatherapy 4: 22.
FLavor FEMA 10-500Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Hepatoprotective 100 ppm
Herbicide
Insecticide
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Irritant
Juvabional Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvicide
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=2,000 ug/mlShoyakugaku Zasshi, 44: 183.
Neurotoxic R.J. Hixtable (Huxtable, R.J. (as T. Max). 1992. This and That:The Essential Pharmacology of Herbs and Spices. Tips 13:15-20 Huxtable, R.J. 1992b. The Myth of Benficent Nature. The Risk of Herbal Preparations. Anns. Intern. Med. 117(2):165-6; Huxtable, R.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
Prostaglandin-Synthesis-Inhibitor 1 mM rbtChen, S. J., Wang, M. H., Chen, I. J. 1996. Antiplatelet and Calcium Inhibitory Properties of Eugenol and Sodium Eugenol Acetate. Gen Pharmacol, 27(4): 629-633.
Prostaglandin-Synthesis-Inhibitor IC50=9.2 uM
Sedative
Termiticide LD100=5 mg/g
Trichomonicide LD100=300 ug/ml
Trichomonistat IC50=10 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Trypsin-Enhancer Lawrence Review of Natural Products, Dec-93.
Ulcerogenic Phytotherapy Research, 4: 93.
Varroacide
Vasodilator
Vermifuge
FURFURAL Plant8.0 24.0 1.4 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (6)
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
FLavor FEMA 1-30Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide
Insecticide
Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Pesticide
GERANIOL Plant3.0 21.0 -0.45 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (35)
Allergenic
Anthelmintic Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
Antibacterial MIC=400 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antibacterial MIC=64 ug/ml
Antibacterial MBC=800 ug/ml
Anticancer (Pancreas) IC50=265 uM
Anticariogenic MIC=400 ug/mlMuroi, H. and Kubo, I. 1993. Combination Effects of Antibacterial Compounds in Green Tea Flavor against Streptococcus mutans. J. Agric. Food Chem. 41: 1102-1105.
Antimelanomic IC50=150 uM/l
Antisalmonella MIC=400 ug/ml
Antiseptic 7 x phenolWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Antiseptic MIC=64 ug/ml
Antiseptic 400-800 ug/ml
Antispasmodic Buchbauer, G., Jirovetz*, L., Nikiforov, A., Remberg, G., Raverdino, V. 1989. Headspace-Analysis and Aroma Compounds of Austrian Hay-Blossoms (Flores Graminis, Graminis Flos) used in Aromatherapy. J. Ess. Oil Res., 2: 185-191, 1990.
Antitubercular MIC=64 ug/ml
Antitumor Yu, S.G., Anderson, P.J., and Elson, C.E. 1995. Efficacy of B-Ionone in the Chemoprevention of Rat Mammary Carcinogenesis. J. Agric. Food Chem. 43: 2144-2147.
Antitumor (Pancreas) IC50=265 uM
Ascaricide Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
CNS-Stimulant List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Embryotoxic
Emetic 3 x ipecacLawrence Review of Natural Products, Sep-97.
Expectorant Madaus, G. 1976. Lehrbuch der Biologischen Hilfmittel. Vol,. 1-3. 2862 pp. (+ 144 p. index). Georg Olms Verlag, Hildescheim. Reprint of 1938 Madaus.
FLavor FEMA 1-10Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide IC93=2 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC100-2,000 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge 50 ppm
Insectiphile Merck 11th Edition
Mycobactericide MIC=64 ug/ml
Nematicide IC86=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Nematicide MLC=1,000 ug/mlShoyakugaku Zasshi, 44: 183.
Perfumery Merck 11th Edition
Pesticide
Sedative
Trichomonicide LD100=300 ug/ml
GERANYL-ACETATE Plant-- -- Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (5)
Allergenic
FLavor FEMA 1-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Insectiphile Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sedative Jim Duke's personal files.
GERANYL-BUTYRATE Plant6.0 28.0 -1.27 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (3)
FLavor FEMA 1-10Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
HEXANOL Plant1.0 7.0 0.07 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (3)
Antiseptic
FLavor FEMA 0.2-25Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
ISOBORNEOL Plant1.0 43.0 0.23 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (7)
Antiherpetic 600 ppm
Antiviral 600 ppm
Insectifuge
Motor-Stimulant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Sedative
LIMONENE Plant55.0 297.0 -0.3 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (60)
AChE-Inhibitor Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Acaricide LC100=8 uM
Allelochemic
Allergenic 1/20th carene
Antiacetylcholinesterase IC22-26=1.2 mM
Antiadenomic
Antialzheimeran? Grundy, D. L. and Still, C. C., Inhibition of acetylcholinesterases by pulegone-1,2-epoxide, Oest. Biochem. & Physiol., 23, 1985, 383-8.
Antiasthmatic
Antibacterial Revista Itiliana Eppos, 12: 5, 1994.
Anticancer
Antiesophagitic
Antifeedant
Antiflu Economic & Medicinal Plant Research, 5: 195.
Antiinflammatory
Antilithic
Antilymphomic
Antimetastatic (Stomach)
Antimutagenic Economic & Medicinal Plant Research, 6: 235.
Antiobesity
Antiseptic
Antispasmodic ED50=0.197 mg/mlFitoterapia No.59-1984.
Antitumor
Antitumor (Breast)
Antitumor (Colon)
Antitumor (Pancreas)
Antitumor (Prostate)
Antitumor (Stomach)
Antiviral
Apoptotic
Bronchoprotectant
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidistat
Chemopreventive
Cholesterolytic
Detoxicant
Enterocontractant J. Aromatherapy 4: 22.
Expectorant
FLavor
Fungiphilic J. Agric. Food Chem. 43: 2283.
Fungistat
GST-Inducer
Herbicide IC50=45 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Histaminic
Immunomodulator
Insecticide 0.37 uM/fly
Insectifuge Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Interleukin-6-Inhibitor
Irritant
Lipolytic
Myorelaxant 50 mg/kg
NO-Genic
Nematicide IC=100 ug/mlNigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Ornithine-Decarboxylase-Inhibitor ~750 mg/kg (diet)
Ozone-Scavenger
P450-Inducer
Peristaltic
Pesticide
Photosensitizer Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Sedative ED=1-32 mg/kgWagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Transdermal
LINALYL-ACETATE Plant1.0 198.0 -0.48 *
Activities (7)
Anesthetic 0.01-1 ug/ml
Antioxidant 400 ppm
Antispasmodic ED50=0.21 mg/mlFitoterapia No.59-1984.
FLavor FEMA 2-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Motor-Depressant Buchbauer et al, e.g.Buchbauer et al,1993.Therapeutic properties of essential oils and fragrances. Chap.12 in Teranishi,R, Buttery,R.G and Sugisawa,H. Eds. Bioactive Volatile Compounds from Plants. ACS Symposium Series 525. Amer. Chem. Soc., Washington DC
Perfumery Merck 11th Edition
Sedative
MYRCENE Plant39.0 74.0 -0.39 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (22)
ACE-Inhibitor 100 ug/ml
Aldose-Reductase-Inhibitor 100 ug/mlOkamura, K., Iwakami, S., Matsunaga, T. 1992. Biological Activity of Monoterpenes from Trees. Toyama-Ken Yakuji Kenkyusho Nenpo, (20): 95-101.
Allergenic
Analgesic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antibacterial
Anticonvulsant
Antimutagenic Kauderer, B., Zamith, H., Paumgartten, F.J.R., and Speit, G. Evaluation of the Mutagenicity of B-Myrcene in Mammalian Cells In Vitro. Environmental and Molecular Mutagenesis 18: 28-34, 1991.
Antinitrosaminic
Antinociceptive 10-20 mg/kg ipr musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antinociceptive 20-40 mg/kg scu musRao, V.S.N., Menezes, A.M.S., Viana, G.S.B. 1990. Effect of myrcene on nociception in mice. J. Pharm. Pharmacol. 42: 877-878, 1990.
Antioxidant Jim Duke's personal files.
Antispasmodic Jim Duke's personal files.
Chemopreventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
FLavor FEMA 0.5-9Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypothermic
Insectifuge
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Myorelaxant 100-200 mg/kg
P450-2B1-Inhibitor IC50=0.14 uM
Perfumery Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Pesticide
NEROL Plant1.0 15.0 -0.43 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (10)
Antibacterial HerbalGram No. 17.
Antihelicobacter
Antiseptic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiulcer
Estrogenic
FLavor FEMA 1-20Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Merck 11th Edition
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide ED100=300 ug/ml
NERYL-ACETATE Plant6.0 28.0 -0.54 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (5)
Antiflu
Antiviral
FLavor FEMA 1-15Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
OLEANOLIC-ACID Leaf-- 4900.0 2.14 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (64)
Abortifacient
AntiHIV IC50=21.8 ug/ml
AntiHIV EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiPGE2 IC50=24 uM
AntiTGF-beta IC50=19-24 uM
Antiallergic
Antiarrhythmic 40 mg/kg
Antiatherosclerotic
Antibacterial MIC=625-1,250 ug/ml
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplement IC40-50 0.01 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antiedemic IC36=40 mg/kg ipr rat
Antifertility
Antigingivitic MIC=625-1,250 ug/ml
Antihepatotoxic
Antihyperlipidemic
Antiinflammatory 40 mg/kg iprAquino, R., De Feo, V., De Simone, F., Pizza, C.*, and Cirino, G. Plant Metabolites. New Compounds And Anti-Inflammatory Activity Of Uncaria tomentosa. Journal of Natural Products, 54(2): 453-459, 1991.
Antiischemic 40 mg/kg
Antileukemic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antileukotriene IC50=17 uM
Antimalarial IC50=70-89 ug/ml
Antinephritic IC50=19-24 uM
Antioxidant Balanehru, S. and Nagarajan, B. 1992. Intervention of Adriamycin Induced Free Radical Damage. Biochemistry International 28(4): 735-744, 1992.
Antioxidant IC46=10 uM
Antiperiodontic MIC=625-1,250 ug/ml
Antiperoxidant IC30=200 ug/ml
Antiplaque MIC=625-1,250 ug/ml
Antiplasmodial IC50=70-89 ug/ml
Antisarcomic
Antiseptic MIC=625-1,250 ug/ml
Antitumor
Antitumor (Breast) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Kidney) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Lung) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Pancreas) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antiulcer >carbenoxolone
Antiviral EC50=1.7 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Antiviral IC50=21.8 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
COX-2-Inhibitor IC50=295 uM/
COX-2-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cardioprotective 40 mg/kg
Cardiotonic
Cyclooxygenase-Inhibitor
Diuretic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective Advance in Chinese Medicinal Materials Research. 1985. Eds. H. M. Chang, H. W. Yeung, W. -W. Tso and A. Koo. World Scientific Publishing Co., Philadelphia Pa., page 211.
Hypolipemic
Hypotensive
Immunomodulator
Leucocytogenic
NF-kB-Inhibitor
Phagocytotic
Piscicide ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Prostaglandin-Synthesis-Inhibitor igs mus
Sedative
Uterotonic
Vasopressor
P-CYMENE Plant26.0 98.0 -0.39 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (16)
Analgesic Martindale's 28th
Antiacetylcholinesterase IC40=1.2 mM
Antibacillary
Antibacterial
Antiflu
Antirheumatalgic Martindale's 28th
Antiviral
FLavor FEMA 12-250Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Herbicide IC50=50 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge Blaschek, W., Hansel, R., Keller, K., Reichling, J., Rimpler, H., and Schneider, G. eds. 1998. Hager's Handbuch der Pharmazeutischen Praxis, Auflage Band 2 (A-K), 909 pp., (L-Z), 858 pp. Springer-Verlag, Berlin.
Irritant Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Laxative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Pesticide
Sedative Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
Trichomonicide LD100=50 ug/ml
ROSMARINIC-ACID Plant-- 7000.0 -1.3 Fitoterapia No.62: 166.
Activities (57)
ABeta-Inhibitor
Adenylate-Cyclase-Inhibitor
Aldose-Reductase-Inhibitor
AntiHIV EC50=40 ug/ml
Antiaggregant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antiallergic
Antialzheimeran
Antianaphylactic 1-100 mg/kg orlInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antianaphylactic ID50=1 mg/kg ivn rat
Antianaphylactic ID50=10 mg/kg ims rat
Antiatherosclerotic IC50=0.74 uM
Antibacterial Planta Medica, 55: 663.
Anticoagulant Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticomplementary 1/2 aspirin
Anticomplementary 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antidepressant
Antiedemic 0.316-3.16 mg/kg imsInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antigonadotropic
Antihemolytic IC70=5-10 um/lInt. J. Immunopharmacology. Vol 10: 729, 1988.
Antihepatotoxic
Antiherpetic 50 ug/mlVlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antiherpetic EC50=20 ug/ml
Antihyperthyroid
Antiinflammatory IC~58=1,000 uM
Antiintegrase 10 ug/ml
Antileukotriene
Antilipoperoxidant
Antimutagenic
Antinephritic
Antioxidant EC50=2.7 ug/mlParveen, N. 1991. Antifilarial Activity of Vitex negundo Against Setaria cervi. Fitoterapia, 62(2): 163, 1991.
Antioxidant 10 uM
Antioxidant (LDL) IC50=0.74 uM
Antiplaque
Antiproliferant
Antiprostaglandin 20 mg/kg ivnNewall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antiproteolytic IC50=0.9 mol lHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antipulmonotic Tyler, V.E.. 1994.
Antiradicular
Antishock Int. J. Immunopharmacology. Vol 10: 735, 1988.
Antithyreotropic
Antithyroid Jim Duke's personal files.
Antiuremic
Antiviral EC50=40 ug/ml
Anxiolytic
Apoptotic
COX-1-Inhibitor IC58=1,000 uM
COX-2-Inhibitor IC>58=1,000 uM
Calcium-Antagonist IC50=1.2 uM rbt
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Cytotoxic TC50=100-150 ug/ml
Deiodinase-Inhibitor Jim Duke's personal files.
Immunomodulator
Immunostimulant
Lipoxygenase-Inhibitor
Neuroprotective
Pesticide
Radioprotective
SABINENE Plant-- 55.0 -0.41 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (5)
Antibacterial
Antihelicobacter
Antiseptic
Antiulcer
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
TERPINEN-4-OL Plant-- 121.0 -0.23 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (23)
Allelopathic Wright,C.W.(Ed)2002.Medicinal&Aromatic Plants-Industrial Profiles.Artemisia.344pp.Maffei,M.(Ed)2002.Vetiveria.The Genus Vetiveria.Taylor&Francis.NY,NY.191pp.Southwell,I.,Lowe,R.(Eds)1999.Tea Tree.The Genus Melaleuca.Harwood Acad.Pub.Amsterdam,Netherlands.
Antiacetylcholinesterase IC21-24=1.2 mM
Antiacne
Antiallergic
Antiasthmatic Chin. J. Tuber. Respir. Dis., 4:203, 1982.
Antibacterial
Antioxidant
Antiseptic Flav. & Frag. J. 9: 129.
Antispasmodic
Antitussive Chin. J. Tuber. Respir. Dis.
Antiulcer
Bacteriostatic Chin. J. Tuber. Respir. Dis.
Diuretic 0.1 ml/rat
Fungicide
Herbicide IC50=200 mMLydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Herbicide IC50=22 uMKeeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Insectifuge
Irritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide MLC=1 mg/mlShoyakugaku Zasshi, 44: 183.
Pesticide
Renoirritant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Spermicide ED100=0.015
Vulnerary Lawrence Review of Natural Products, Jan-91.
TERPINOLENE Plant13.0 28.0 -0.49 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (9)
Allelochemic
Antifeedant
Antinitrosaminic
Antioxidant
Deodorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 15-60Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Perfumery Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide
TRANS-CARVEOL Plant1.0 3.0 -0.72 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Activities (1)
Antiasthmatic
URSOLIC-ACID Leaf10000.0 19000.0 0.01 List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Activities (89)
Analgesic
AntiEBV Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
AntiHIV EC50=2.0 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC50=6.5 ug/mlKashiwada, Y., et. al. 1998. Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids. J. Nat. Prod., 61 (9): 1090-1095.
AntiHIV IC85=18 ug/ml
AntiHIV 6.7 uM
AntiTGF-beta IC50=6-7.5 uM
Antialzheimeran Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Antiarrhythmic
Antiarthritic Planta Medica, 57: A56, 1991.
Antibacterial
Anticancer Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticancer (Colon) Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Anticarcinomic Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Anticariogenic Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Anticholestatic 28-100 mg/kg orlShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Anticomplement IC100 0.1 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Anticomplement IC80-90 0.05 mM/l gpgHansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Antidiabetic Chemical Constituents of Oriental Herbs (3 diff. books)
Antiedemic
Antiescherichic
Antifibrosarcomic IC80=10 uM
Antihepatotoxic 5-20 mg/kg iprShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antihistaminic Tsuruga, T., Chun, Y.-T., Ebizuka, Y., and Sankawa, U. 1991. Biologically Active Constituents of Melaleuca leucadendron: Inhibitors of Induced Histamine Release from Rat Mast Cells. Chem. Pharm. Bull. 39(12): 3276-3278, 1991.
Antihyperlipidemic
Antiinflammatory 1/3 indomethacin
Antiinflammatory IC24=500 mg/kg
Antileishmanic ED50=20 uM
Antileukemic IC50=2.5-17.8 ug/ml
Antilymphomic Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Antimalarial IC50=28-37 ug/ml
Antimetastatic IC80=10 uM
Antimutagenic IC57-80=80 mg/kg
Antinephritic IC50=6-7.5 uM
Antiobesity? Internat. J. Oriental Med. 16: 4.
Antioxidant IC50=10 uM
Antiperoxidant IC35=200 ug/ml
Antiplasmodial IC50=28-37 ug/ml
Antiproliferative IC50=15-20 uM
Antistaphylococcic
Antithromboxane IC50=50 uM
Antitrypanosomic
Antitumor Cancer Research, 54: 701, 1994.
Antitumor (Breast) 0.5% diet
Antitumor (Breast) IC50=15-20 uM
Antitumor (Cervix) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Colon)
Antitumor (Lung)
Antitumor (Ovary) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor (Stomach) IC50=15-20 uM
Antitumor (brain) Chiang, L. C., Chiang, W., Chang, M. Y., Ng, L. T., Lin, C. C. 2003. Antileukemic activity of selected natural products in Taiwan. Am J Chin Med, 31(1):37-46.
Antitumor-Promoter Planta Medica, 57: A56, 1991.
Antiulcer Shukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Antiviral IC85=18 ug/ml
Aromatase-Inhibitor
Beta-Blocker
Beta-Glucuronidase-Inhibitor ~100 mg/kg
CNS-Depressant
COX-2-Inhibitor IC50=130 uM/
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide
Cardioprotective
Cardiotonic
Choleretic 5-20 mg/kg orlShukla, B., Visen, P.K.S., Patnaik, G.K., Tripathi, S.C., Srimal, R.C., Dayal, R., and Dobhal, P.C. Hepatoprotective Activity in the Rat of Ursolic Acid Isolated from Eucalyptus Hybrid. Phytotherapy Research 6: 74-79, 1992.
Cyclooxygenase-Inhibitor Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
Cytotoxic 50 ppm
Cytotoxic ED50=3.75 ug/ml
Cytotoxic 7.2 uM
Diuretic
Elastase-Inhibitor IC50=~15 uM
Hepatoprotective 1-100 ug/ml
Hepatoprotective 10 mg/kg
Hypoglycemic Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
Hypotensive
Immunomodulator
Leucocytogenic
Lipoxygenase-Inhibitor IC50=0.18 mM
MMP-9-Inhibitor IC80=10 uM
Ornithine-Decarboxylase-Inhibitor
Pesticide
Piscicide
Potassium-Sparing 3 mg/ratIwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
Protease-Inhibitor IC85=18 ug/ml
Protisticide Chemical Express, 7: 285, 1992.
Quinone-Reductase-Inducer 5 ug/mlLee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
Sodium-Sparing 3 mg/ratIwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp.
TOPO-2-Inhibitor
Trypanocide
Vasopressor
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.