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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical HARRINGTONINE

Chemical ID
HARRINGTONINE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=4.3 mg/kg (ipr mus) Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Anticarcinomic 0.5-1 ppm *
Antileukemic (2 ppm), 2-4 mg Martindale's 29th
Antimelanomic ED50=0.077 ug/ml J. Ethnopharmacology, 32: 117.
Antisarcomic ED50=0.01 ug/ml J. Ethnopharmacology, 32: 117.
Antitumor (Breast) ED50=0.017 ug/ml J. Ethnopharmacology, 32: 117.
Antitumor (Colon) ED50=0.014 ug/ml J. Ethnopharmacology, 32: 117.
Antitumor (Lung) ED50=0.036 ug/ml J. Ethnopharmacology, 32: 117.
DNA-Synthesis-Inhibitor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
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