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ActivityReference
Abortifacient Rodrigues de Almeida, E., Melo, A. M., Xavier, H. 2000. Toxicological Evaluation of the Hydro- alcohol Extract of the Dry Leaves of Peumus boldus and Boldine in Rats. Phytotherapy Research, 14(2): 99-102.
Antidiabetic *
Antiedemic ED50=34 mg/kgAbstract (See species file)
Antihepatotic *
Antiinflammatory ED50=34 mg/kg*
Antilithic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antimutagenic *
Antioxidant IC50=17-33 ug/ml*
Antiprostaglandin IC53=75 uMAbstract (See species file)
Antipyretic ED51-98=60 mg/kg orl rbtAbstract (See species file)
Antiradicular *
Beta-Adrenergic Receptor Blocker 0.1 uMde las Heras, B., Rios, J. L., Martinez-Mir, I., Rubio, E. 1990. A Study of the Adrenergic Activity of the Alkaloids Boldine and Glaucine. Pharmazie, 45(6): 443-444.
Calcium-Channel-Blocker 1/70th diltiazem*
Chemopreventive *
Choleretic Fitoterapia No.5-1986.
Convulsant Grieve's Modern Herbal.
Diuretic *
Gastrostimulant Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Hepatoprotective *
Hydrogen-Peroxide-Inhibitor *
Hypnotic Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Immunomodulator *
Myorelaxant *
Neuroleptic *
NO-Inhibitor *
Prostaglandin-Synthesis-Inhibitor 25 uM ratBackhouse, N., Delporte, C., Givernau, M., Cassels, B. K., Valenzuela, A., Speisky, H. 1994. Anti-Inflammatory and Antipyretic Effects of Boldine. Agents & Actions, 42(3/4): 114-117.
Teratogenic Rodrigues de Almeida, E., Melo, A. M., Xavier, H. 2000. Toxicological Evaluation of the Hydro- alcohol Extract of the Dry Leaves of Peumus boldus and Boldine in Rats. Phytotherapy Research, 14(2): 99-102.
Uricosuric Wichtl, M. 1984. Teedrogen. Ein Handbuch fur Apotheker und Arzte. Wissenschaftliche Verlagsgesellscharft. mbH Stuttgart. 393 pp.
Vasoconstrictor 1/70th diltiazem*
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.