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Total Activities: 14
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Activity *Reference
Antiherpetic 414 ppb Bedows, E. and Hatfield, G.M. An Investigation of the Antiviral Activity of Podophyllum peltatum. J. Nat. Prod. 45: 725.
Antiherpetic IC50=0.025 uM *
Antileukemic 4.7 ppb *
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antistomatitic IC50=0.025 uM *
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral MIC=38 nM *
Antiviral IC50=0.025 uM *
Artemicide 150 ppb *
Cytotoxic 4-400 ppm Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Herbicide *
Insecticide *
Topoisomerase-II-Inhibitor 10 ug/ml Figgitt, D. P., Denyer, S. P., Dewick, P. M., Jaackson, D. E., Williams, P. Differential Sensitivity of Fungal Topoisomerases to Podophyllotoxin Derivatives. J Pharm Pharmacol Suppl, 41: 44pp.
Topoisomerase-II-Inhibitor IC50=186.5 uM Terada, T., et al. 1992. Antitumor Agents. I. DNA Topoisomerase II Inhibitory Activity and the Structural Relationship of Podophyllotoxin Derivatives as Antitumor Agents. Chem Pharm Bull, 40: 2720-2727.
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.