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Total Activities: 19
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Activity *Reference
Anticarcinomic 70 ppb *
Antiherpetic *
Antileukemic 0.5-4 mg/kg *
Antimelanomic ED50=0.14 ug/ml J. Ethnopharmacology, 32: 117.
Antipsoriac *
Antisarcomic ED50=0.0095 ug/ml J. Ethnopharmacology, 32: 117.
Antitumor (Breast) ED50=0.043 ug/ml J. Ethnopharmacology, 32: 117.
Antitumor (Colon) ED50=0.047 ug/ml J. Ethnopharmacology, 32: 117.
Antitumor (Lung) ED50=0.024 ug/ml J. Ethnopharmacology, 32: 117.
Antiviral Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Insecticide *
Interferonogenic *
Pesticide *
Topoisomerase-I-Inhibitor ED50=0.8 uM Hertzberg, R. P., et al. 1989. Modification of the Hydroxy Lactone Ring of Camptothecin: Inhibition of Mammalian topoisomerase I and Biological Activity. J Med Chem, 32: 715-720.
Topoisomerase-I-Inhibitor IC50=1 uM Weller, M., et al. 1997. Topoisomerase I Inhibitors For Human Malignant Glioma: Differential Modulation of P53, P21, BAX and BEL-2 Expression and of CD95-Mediated Apoptosis. Int J Cancer, 73: 707-714.
Topoisomerase-I-Inhibitor IC50=670 nM Luzzio, M. J., et al. 1995. Synthesis and Antitumor Activity of Novel Water Soluble Derivatives of Camptothecin as Specific Inhibitors of Topoisomerase I. J Med Chem, 38: 395-401.
Topoisomerase-I-Inhibitor 1-50 uM *
Topoisomerase-I-Poison Journal of Medicinal Food 2: 167.1999.
Topoisomerase-II-Inhibitor Rose, K. M. 1988. DNA Topoisomerases as Targets for Chemotherapy. Faseb J, 2: 2474-2478.
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.