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Total Activities: 176
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Activity *Reference
11B-HSD-Inhibitor *
5-Lipoxygenase-Inhibitor IC50 (uM)=4 *
Aldehyde-Oxidase-Inhibitor IC70-96=10 uM *
Aldose-Reductase-Inhibitor IC50=0.344 uM Mao, X. M., Zhang, J. Q. 1993. Inhibition of Aldose Reductase by Extracts of Chinese Herbal Medicine. Zhongguo Zhongyao Zazhi , 18(10): 623-624.
Aldose-Reductase-Inhibitor IC50=0.84 ug/ml cow Okada,Y,et al.1995.Search for Naturally Occurring Substances to Prevent the Complications of Diabetes.II.Inhibitory Effect of Coumarin and Flavonoid Derivatives on Bovine Lens Aldose Reductase and Rabbit Platelet Aggregation.Chem Pharm Bull43(8):1385-1387
Aldose-Reductase-Inhibitor 4 ug/ml Ichikawa, K., et al. 1991. Isolation and Structure Determination of Aldose Reductase Inhibitors from Traditional Thai Medicine, and Syntheses of Their Derivatives. Sankyo Kenkyusho Nempo, 43: 99-110.
Aldose-Reductase-Inhibitor 100 uM *
Allelochemic IC82=1 mM Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Allergenic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Analgesic *
Antiaflatoxin IC50=7.5 ppm *
Antiaflatoxin IC50=25 uM *
Antiaggregant IC50=55 uM Economic & Medicinal Plant Research, 5: 333.
Antiaggregant 30 uM *
Antiaging *
Antiallergic IC50=14 uM Jim Duke's personal files.
Antialzheimeran *
Antianaphylactic Meli, R., Autore, G., Di Carlo, G., Capasso, F. Inhibitory Action of Quercetin on Intestinal Transit in Mice. Phytotherapy Research 4(5): 201, 1990.
Antiangiogenic *
Antiarthritic *
Antiasthmatic IC50=14 uM *
Antiatherosclerotic *
Antibacterial Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Anticarcinomic (Breast) IC50=1.5 uM Medline (post 1990 searches filed in my computer)
Anticariogenic ID50=120 ug/ml *
Anticataract *
Anticolitic 400 mg/man/3x/day Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticomplementary *
AntiCrohn's 400 mg/man/3x/day Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Anticystitic 1,000 mg/day/4 weeks *
Antidepressant *
Antidermatitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antidiabetic *
Antielastase IC50=0.8 ug/ml *
Antiencephalitic Economic & Medicinal Plant Research, 5: 199.
Antiescherichic *
Antiestrogenic *
Antifeedant IC52=<1,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Antifibrosarcomic *
Antiflu Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antigastric Rastitel'nye Resursy, 21: 85.
Antigonadotropic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
AntiGTF ID50=120 ug/ml *
Antihepatotoxic Joyeux, M., Rolland, A., Fleurentin, J., Mortier, F., and Dorfman, P. 1989. Tert-Butyl Hydroperoxide-Induced Injury in Isolated Rat Hepatocytes: A Model for Studying Anti-Hepatotoxic Crude Drugs. Planta Medica 56(2): 171-173, 1990.
Antiherpetic 48-150 ug/ml *
Antihistaminic IC50=<10 uM *
AntiHIV *
Antihydrophobic Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
Antihypertensive Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiinflammatory 20-150 mg/kg Fitoterapia No.5-1990.
Antileishmanic IC50=64 *
Antileukemic 5.5-60 uM *
Antileukemic IC50=>10 ug/ml Life Sciences 55: 1061.
Antileukemic IC50=10 uM Economic & Medicinal Plant Research, 5: 225.
Antileukotriene Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antilipoperoxidant IC67=50 *
Antimalarial IC50=1-6.4 ug/ml Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987.
Antimelanomic *
Antimetastatic *
Antimutagenic ID50=0.62 ug/ml *
Antimutagenic ID50=2-5 nM Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antimyocarditic Economic & Medicinal Plant Research, 5: 199.
Antinitrosaminic *
Antinociceptive *
Antioxidant IC47=10 uM *
Antioxidant IC96=300 ppm Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Antioxidant 4.7 x Vit. E *
Antioxidant ED50=2.3 uM Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Antipancreatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antiperiodontal Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiperistaltic *
Antipermeability *
Antiperoxidant Planta Medica, 57: A110, 1991.
Antipharyngitic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplaque Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiplasmodial IC50=13-64 *
AntiPMS 500 mg/2x/day/wmn Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antipodriac *
Antipolio Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiproliferant 10 nM *
Antiprostanoid *
Antiprostatitic Joseph, J., Nadeau, D. and Underwood, A. 2001. The Color Code. Hyperion, NY.
Antipsoriac Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiradicular IC50=4.6 uM Planta Medica, 56(6): 695, 1990.
Antispasmodic *
Antistreptococcic ID50=120 ug/ml *
Antithiamin Phenolic Compounds in Food and Their Effects on Health, 69.
Antithrombic *
Antitrypanosomic IC50=13 *
Antitumor 10 uM *
Antitumor (Bladder) *
Antitumor (Breast) *
Antitumor (Colon) *
Antitumor (Lung) *
Antitumor (Ovary) *
Antitumor (Skin) 20 uM *
Antitumor-Promoter Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Antiulcer *
Antiviral IC50=10 uM Economic & Medicinal Plant Research, 5: 225.
Antiviral 48-150 ug/ml Amoros, M., Simoes, C.M.O., Girre, L., et al. Synergistic Effect Of Flavones And Flavonols Against Herpes Simplex Virus Type 1 In Cell Culture. Comparison With The Antiviral Activity Of Propolis. J. of Natural Products 55(12):1732-1740, 1992.
Apoptotic 20-60 uM *
ATPase-Inhibitor Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Bacteristat 10 mg/ml *
Bradycardiac Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Calmodulin-Antagonist Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
cAMP-Phosphodiesterase-Inhibitor Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Cancer-Preventive Stitt, P. A. Why George Should Eat Broccoli. Dougherty Co, Milwaukee, WI, 1990, 399 pp.
Candidicide *
Capillariprotective Merck 11th Edition
Carcinogenic 40,000 ppm (diet) mus Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Catabolic *
COMT-Inhibitor *
Copper-Chelator *
COX-2-Inhibitor <40 uM *
Cyclooxygenase-Inhibitor *
Cytochrome-P450-1A2-Inhibitor *
Cytotoxic IC82=100 ug/ml Planta Medica, 57: A113, 1991.
Cytotoxic ED50=70 ug/ml Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
Deiodinase-Inhibitor Jim Duke's personal files.
Diaphoretic? Lawrence Review of Natural Products, Dec-90.
Differentiator 5.5 uM *
Estrogenic 10% genistein *
Fungicide *
Glucosyl-Transferase-Inhibitor ID50=120 ug/ml *
Hemostat Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Hepatomagenic 5,000 ppm (diet) rat Phenolic Compounds in Food and Their Effects on Health. Antioxidants & Cancer Prevention. Huang, M.T., Ho, C.T. and Lee, C.Y. eds. 1992. ACS Symposium Series 507.ACS, Washington 402 pp.
Hepatoprotective *
HIV-RT-Inhibitor IC50=<1 ug/ml Nakane, H., Fukushima, M., and Ono*, K. Differential Inhibition Of Reverse Transcriptase And Various DNA Polymerases By Digallic Acid And Its Derivatives. Journal of Natural Products, 53(5): 1234-1240, 1990.
Hypoglycemic 100 mg/kg orl rat Ivorra, M.D., Paya, M., and Villar, A. 1989. A Review of Natural Products and Plants as Potential Antidiabetic Drugs. Journal of Ethnopharmacology, 27: 243-275, 1989.
iNOS-Inhibitor IC50=20 uM *
Inotropic *
Insulinogenic Pizzorno, J.E. and Murray, M.T. 1985. A Textbook of Natural Medicine. John Bastyr College Publications, Seattle, Washington (Looseleaf).
Juvabional Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Larvistat 8,000 ppm diet Lydon, J. & Duke, S., The potential of pesticides from plants, pp. 1-41 in Craker, L. & Simon, J., eds, Herbs, Spices & Medicinal Plants: Recent Advances in Botany, Horticulture, & Pharmacology, v. 4, Oryx Press, Phoenix, 1989, 267pp.
Lipoxygenase-Inhibitor IC50=0.1-5 uM *
Lipoxygenase-Inhibitor IC11=1.25 mM Oszmianski, J. and Lee, C.Y. 1990. Inhibitory Effect of Phenolics on Carotene Bleaching in Vegetables. J. Agric. Food Chem. 38: 688-690.
MAO-A-Inhibitor *
Mast-Cell-Stabilizer *
Metal-Chelator (Copper) Seidel, V., Verholle, M., Malard, Y., Tillequin, F., Fruchart, J-C., Duriez, P., Bailleul, F., Teissier, E. 2000. Phenylpropanoids from Ballota nigra L. Inhibit in vitro LDL Peroxidation. Phytotherapy Research, 14(2): 93-98.
Metalloproteinase-Inhibitor IC50=>42 uM *
MMP-9-Inhibitor 20 uM *
Mutagenic *
NADH-Oxidase-Inhibitor *
NEP-Inhibitor IC50=>42 uM *
Neuroprotective 5-25 uM *
NF-kB-Inhibitor *
NO-Inhibitor IC50=20 uM *
NO-Inhibitor IC>50=125 uM *
NO-Synthase-Inhibitor 5-50 uM *
Ornithine-Decarboxylase-Inhibitor <10 uM *
P450-Inducer 5 uM Father Nature's Farmacy: The aggregate of all these three-letter citations.
P450-Inhibitor 50-100 uM Father Nature's Farmacy: The aggregate of all these three-letter citations.
Pesticide *
PGE2-Inhibitor *
Phospholipase-Inhibitor *
Plasmodicide Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp.
Proliferant *
Prostaglandin-Synthesis-Inhibitor 40 ug/ml Ibewuike, J. C., Ogungbamila, F. O., Ogundaini, A. O., Okeke, I. N., Bohlin, L. 1997. Antiinflammatory and Antibacterial Activities of C-methylflavonol from Piliostigma thonningii. Phytotherapy Research, 11(4): 281-284.
Protein-Kinase-C-Inhibitor Naim, M., Zehavi, U., Nagy, S., and Rouseff, R.L. Hydroxycinnamic Acids as Off-Flavor Precursors in Citrus Fruits and Their Products. Phenolic Compounds in Food and Their Effects on Health, Ch.14.
PTK-Inhibitor 0.4-24 uM *
Quinone-Reductase-Inducer 13 uM *
Quinone-Reductase-Inducer 6 uM Uda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
Teratologic *
TNF-alpha-Inhibitor IC50=3.11 uM *
Topoisomerase-I-Inhibitor IC50=42 uM *
Topoisomerase-I-Inhibitor IC50=12.8 ug/ml *
Topoisomerase-II-Inhibitor IC50=1-6.9 ug/ml *
Topoisomerase-II-Inhibitor IC50=23-40 uM *
Tumorigenic 0.1% diet orl rat/yr Jim Duke's personal files.
Tyrosinase-Inhibitor ID50=70 uM *
Tyrosine-Kinase-Inhibitor Economic & Medicinal Plant Research, 6: 170.
Vasodilator *
VEGF-Inhibitor *
Xanthine-Oxidase-Inhibitor IC50=>0.4 ug/ml Chem. & Pharm. Bull. 38: 1772.
Xanthine-Oxidase-Inhibitor 3.1 uM *
Xanthine-Oxidase-Inhibitor IC50=10.6 ug/ml *
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.