A Aldose-Reductase-Inhibitor PDF

Back to previous
  1. Data Views

    All Chemicals: 314
      CSV   Excel   PDF
    Show All 12345678910..16Next
    Click on column headings to sort the list on the column
    Chemical Dosage References
    (+)-CORYDALINE 50 uM (weak activity)Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459.
    (+)-GLAUCINE 50 uMKubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459.
    (-)-DANSHEXINKUN IC50=0.87 uMTezuka, Y., Kasimu, R., Basnet, P., Namba, T., Kadota, S. 1997. Aldose Reductase Inhibitory Constituents of the Root of Salvia miltiorhiza Bunge. Chem Pharm Bull, 45(8): 1306-1311.
    (-)-EPIGALLOCATECHIN --*
    (-)-EPIGALLOCATECHIN-GALLATE --*
    (-)-STYLOPINE 50 uMKubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459.
    (-)-TETRAHYDROCOLUMBAMINE 50 uM (weak activity)Kubo, M., et al. 1994. Studies on Anti-cataract Drugs from Natural Sources. I. Effects of a Methanolic Extract and the Alkaloidal Components from Corydalis Tuber on in vit Aldose Reductase Activity. Biol Pharm Bull, 17(3): 458-459.
    1,2,3,6-TETRA-O-GALLYOL-BETA-D-GLUCOSE IC50=0.63 uM*
    1,3,6-TRIHYDROXY-2,7-DIMETHOXY-XANTHONE 0.1 uMIketani, Y., Mihashi, H., Sato, S., Takeda, H. 1992. Xanthones as Aldose Reductase Inhibitors. Patent, Japan Kokai Tokkyo Koho-04 139,180: 7pp.
    1,6,7-TRIHYDROXY-2,3-DIMETHOXY-XANTHONE --Mao, S.L., Liao, S. X., Wu, J. H., Liang, H. Q., Chen, H. S., Zhang, C. K. 1996. Studies on Chemical Constituents of Polygala arillat a Buch-Ham. Yao Hsueh Hsueh Pao, 31(2): 118-121.
    1-HYDROXY-3,6,7-TRIMETHOXY-XANTHONE 0.1 uMIketani, Y., Mihashi, H., Sato, S., Takeda, H. 1992. Aldose Reductase Inhibitors Containing Natural Xanthones and Their Synthetic Analogs. Patent, Japan Kokai Tokkyo Koho-04 139,179, 12pp.
    1-METHOXY-2,3-METHYLENEDIOXY-XANTHONE --Mao, S.L., Liao, S. X., Wu, J. H., Liang, H. Q., Chen, H. S., Zhang, C. K. 1996. Studies on Chemical Constituents of Polygala arillat a Buch-Ham. Yao Hsueh Hsueh Pao, 31(2): 118-121.
    13',II8-BIAPIGENIN IC25=10 uMShimizu, M., Ito, T., Terashima, S., Hayashi, T., Arisawa, M., Morita, N., Kurokawa, S., Ito, K., and Hashimoto, Y. 1984. Inhibition of Lens Aldose Reductase by Flavonoids. Phytochemistry, 23: 1885-1888.
    2'O-ACETYLACETOSIDE IC50=0.19 uM*
    2-METHYL-5-(PENTADEC-CIS-8-ENYL)-RESORCINOL IC50=300.7 uMToyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254.
    2-METHYL-5-(PENTADECA-CIS-8-CIS-11-DIENYL)-RESORCINOL IC50=118 uMToyomizu, M., Sugiyama, S., Jin, R. L., Nakatsu, T. 1993. Alpha-Glucosidase and Aldose Reductase Inhibitors: Constituents of Cashew, Anacardium occidentale, Nut Shell Liquids. Phytotherapy Research, 7(3): 252-254.
    2-PHENYL-ETHYL-O-BETA-D-XYLOPYRANOSYL-(1,6)-BETA-D-GLUCOSIDE --Nishimura, H., Morota, T., Yamaguchi, T., Chin, M. 1990. Extraction of Phenethyl Alcohol Derivatives as Aldose Reductase Inhibitors for Treatment of Diabetes-Related Diseases. Patent, Japan Kokai Tokkyo Koho-02 36,189. 13pp.
    28-HYDROXY-FRIEDELANE-1,3-DIONE IC50=12 ug/mlChavez, H., Estevez-Braun, A., Ravelo, A. G., Gonzalez, A. G. 1998. Friedelane Triterpenoids from Maytenus macrocarpa. J. Nat. Prod., 61(1): 82-85.
    3',4',5,6,7-PENTAACETOXY-8-METHOXY-FLAVONE 10 uM (strong activity)Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822.
    3',4',6-TRIHYDROXY-5,7,8-TRIMETHOXY-FLAVONE 10 uM (strong activity)Okuda, I., Muwa, B., Inagakat, K., Horie, T., Nakayama, M. 1982. Inhibition of Aldose Reductases from Rat and Bovine Lenses by Flavonoids. Biochem Pharmacol, 31(23): 3807-3822.
    *Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.