A Xanthine-Oxidase-Inhibitor PDF

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    Chemical Dosage References
    (+)-CATECHIN --Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill Livinston, Edinburgh.
    (-)-EPICATECHIN IC50=>40Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    (-)-EPIGALLOCATECHIN IC50=>40Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    (-)-EPIGALLOCATECHIN-GALLATE IC50=>40Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    (1'S)-1'-ACETOXYCHAVICOL-ACETATE --*
    (Z,E)-2-(3,4-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.021 ug/mlChem. & Pharm. Bull. 38: 1772.
    (Z,E)-2-(3,5-DIHYDROXYPHENYL)-ETHENYL-ESTER IC50=0.124 ug/mlChem. & Pharm. Bull. 38: 1772.
    1,2,3,6-TETRA-O-GALLYOL-BETA-D-GLUCOSE IC50=12 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    1,2,6-TRI-O-GALLOYL-BETA-D-GLUCOSE IC50=39 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    1,3,4,6-TETRA-O-GALLOYL-BETA-D-GLUCOSE IC50=8 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    3,5-DI-O-CAFFEOYLQUINIC-ACID IC50=34 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    3-O-GALLOYLEPICATECHINS IC50=4-7Hatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    AESCULETIN IC52=10 uM*
    ALLICIN 500 uMLAWSON in Koch, H. P. and Lawson, L. D., eds. 1996. Garlic- The Science and therapeutic application of Allium sativum L. and related species. Williams & Wilkins, Baltimore. 329 pp.
    ALLOPURINOL IC50=0.17 uMHatano, T., Yasuhara, T., Yoshihara, R., Agata, I., Noro, T., and Okuda, T. 1989. Effects of Interaction of Tannins with Co-existing Substances.VII. Inhibitory Effects of Tannins Related Polyphenols on Xanthine Oxidase. Chem. Pharm. Bull. 38(5): 1224-1229
    ALLOPURINOL 0.021 ug/ml*
    APIGENIN 0.36 uM*
    ASTRAGALIN-2''-GALLATE 50 uM*
    ASTRAGALIN-6''-GALLATE 50 uM*
    ATHYRIOL --Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
    *Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.