CINCHONINE | LD50=152 (ipr rat) | Merck 11th Edition |
ICAJINE | IC50=>80-95 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALPHA-SELINENE | IC50=>50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CYPERENE | IC50=>50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BETA-SELINENE | IC50=>50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VOMICINE | IC50=>30 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
QUINDOLINE | IC50=>229 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CORYNANTHINE | IC50=>200 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALPHA-YOHIMBINE | IC50=>200 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CRYPTOLEPINOIC-ACID | IC50=>181 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
LIMONIN | IC50=>100 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
RUTIN | IC50=>100 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
ALSTONERINE | IC50=9.7-46.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CRYPTOQUINDOLINE | IC50=9.1-34.6 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROBERTSONINE-B | IC50=9->23.7 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DAMNACANTHAL | IC50=9-83 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ISOCHONDRODENDRINE | IC50=892 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
HUMULENE | IC50=86 ug/ml | * |
(-)-CORYDALMINE | IC50=840-2840 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CORYNANTHEINE | IC50=81 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
MACRALSTONINE | IC50=8.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
5,7-DIMETHOXY-8-(3'-HYDROXY-3'-METHYL-1'-BUTENE) | IC50=8.8-16.25 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ARBORININE | IC50=8.5 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
RUBIADIN-1-METHYL-ETHER | IC50=8-83 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DENTATIN | IC50=8-12 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-A | IC50=8 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
HYDROXYCRYPTOLEPINE | IC50=77-102 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
OLEANOLIC-ACID | IC50=70-89 ug/ml | * |
ISOFRAXIDIN | IC50=7.95 ug/ml | * |
SUNGUCINE | IC50=7.8-10.1 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TOMENTOSRIN | IC50=7.8 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
8-EPIXANTHIN-1,5-EPOXIDE | IC50=7.8 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
20-EPIANTIRHINE | IC50=7.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TRANS-PINOCARVYL-HYDROPEROXIDE | IC50=7.5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ARTEINCULTON | IC50=7.5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
6-ACETYLSWIETENOLIDE | IC50=7.5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AKAGERINE | IC50=7 mg/ml | Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. |
EVOXANTHINE | IC50=67.6 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
DIHYDROCORYNANTHEINE | IC50=66 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
EUPATORIN | IC50=65 uM | * |
DIOSPYRIN | IC50=626 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANHYDROLYCORINE | IC50=6.1-6.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TERMILIGNAN | IC50=6-9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PLEIOCARPAMINE | IC50=6-20 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-THAICANINE | IC50=550-1,610 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VILASININ-1,3-DIACETATE | IC50=50 ug/mL) | * |
KHAYANTHONE | IC50=50 ug/mL) | * |
3-DESACETYLYKHIVORIN | IC50=50 ug/mL) | * |
SALANNIN | IC50=50 ug/ml | * |
NIMBANDIOL | IC50=50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GEDUNIN | IC50=50 ug/ml | * |
11-BETA-ACETOXYKHIVORIN | IC50=50 ug/ml | * |
NIMOCINOL | IC50=50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3-DEACETYLKHIVORIN | IC50=50 ug/ml | Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982. |
ISOMELDENIN | IC50=50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NIMBIN | IC50=50 ug/ml | * |
ENTANDROPHRAGMIN | IC50=50 | * |
3-METHYLNAPHTHARAZIN | IC50=5.8 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALPHA-CYPERONE | IC50=5.5 ug/ml | * |
SECURINE | IC50=5.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
MELDENIN | IC50=5.2 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
1(S)-HYDROXY-ALPHA-BISABOLOLOXIDE | IC50=5.09 ug/ml | * |
12-METHOXY-NB-METHYLVOACHOLATINE | IC50=5->5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NB-METHYLAFFINISINE | IC50=5->5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AFFINISINE | IC50=5->5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
16-EPIAFFININE | IC50=5->5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VIROLONGIN-A | IC50=5-6 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
MYRTENAL | IC50=5-50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
MYRTENOL | IC50=5-50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TRANS-PINOCARVEOL | IC50=5-50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
N-ISOBUTYLDECA-2,4-DIENAMIDE | IC50=5-5.4 ug/ml | * |
ANCISTROBREVINE | IC50=5-25 ug/ml | * |
ANCISTROCLADINE | IC50=5-25 ug/ml | * |
7-DEACETYLKHIVORIN | IC50=5 ug/ml | * |
METHYLANGOLENSATE | IC50=5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEINE-C | IC50=5 ng/ml | Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. |
SKIMMIANINE | IC50=48.2 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
(-)-ASIMILOBINE | IC50=470-950 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-NOR-DICENTRINE | IC50=470-1030 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
LUPEOL | IC50=46.8 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
ALSTONERINE | IC50=46.3 uM | * |
SIPANDINOLIDE | IC50=46 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-XYLOPINE | IC50=440-2,270 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
11-METHOXYAKUAMMICINE | IC50=41.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CORYNANTHEDINE | IC50=41 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TALCARPINE | IC50=40.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROBERTSONINE-D | IC50=4.8 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
QUINIDINONE | IC50=4.7 ug/ml | Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. |
EXIGUAFLAVANONE-A | IC50=4.6-7.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROBERTSONINE-C | IC50=4.5-10.1 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ACACETIN | IC50=4.2-12.6 ug/ml | * |
DIUVARETIN | IC50=4.2 ug/ml | * |
ASIMICIN | IC50=4 ppm | Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238. |
HEXAMETHOXYLIGNAN | IC50=37-50 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CIRSILINEOL | IC50=36 uM | * |
(-)-CURINE | IC50=353 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CARYOPHYLLENE-16-ALPHA-OXIDE | IC50=345 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CHRYSOSPLENOL-D | IC50=32 uM | * |
XANTHUMIN | IC50=31 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GLINOSIDE-A | IC50=30-42 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BISNORDIHYDROTOXIFERINE | IC50=3.8-4.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ETHYL-CRYPTOLEPIDONOATE | IC50=3.8 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
7-DEACETYLGEDUNIN | IC50=3.6 ug/ml | Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982. |
TILIACORININE | IC50=3.5 ug/ml | * |
11-BETA-ACETOXYGEDUNIN | IC50=3.11 ug/ml | * |
HEPTAPHYLLINE | IC50=3-6 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-D-4''-O-GLUCOSIDE | IC50=3-5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3,4,5-TRIMETHOXYPHENYL(6'-O-GALLOYL)-O->D-GLUCOPYRANOSIDE | IC50=3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AZADIRADIONE | IC50=3 ug/ml | Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982. |
1-O-ACETYLNORPLUVIININE | IC50=28.3-34.2 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
URSOLIC-ACID | IC50=28-37 ug/ml | * |
OSTHOL | IC50=25.1 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
ALPINUMISOFLAVONE | IC50=24.6 ug/ml | Khalid, S.A., Farouk, A., Geary**, T.G., and Jensen, J.B. 1985. Potential Antimalarial Candidates From African Plants: An In Vitro Approach Using Plasmodium falciparum*. Journal of Ethnopharmacology, 15: 201-209, 1986. |
CASTICIN | IC50=24 uM | * |
CHRYSOSPLENETIN | IC50=23 uM | * |
AJUGARIN-I | IC50=23 uM | * |
(-)-CASSYTHICINE | IC50=2260-2290 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TRIGILLETIMINE | IC50=22 ug/ml (ca 1/200 x chloroquine) | * |
ANOLIGNAN | IC50=20 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-CRINAMINE | IC50=2.8-3.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(8',9'-DIHYDROXY)-3-FARNESYLINDOLE | IC50=2.8 ug/ml | * |
1-HYDROXYBENZOISOCHROMAN | IC50=2.7 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DIHYDROGEDUNIN | IC50=2.63 ug/mL | * |
VOACOMINE | IC50=2.6->5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DIHYDROBRUCEAJAVIN-A | IC50=2.5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
10,12-PEROXYCALAMENENE | IC50=2.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
YOUNDAMINE-A | IC50=2.2 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CROSTPARINE | IC50=2.1-3.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROHEYNINE-A | IC50=2.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROBREVINE-B | IC50=2-4.7 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
KORUPENSAMINE-E | IC50=2 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEANTINOL | IC50=2 ng/ml | Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. |
5,6,7-TRIMETHOXYCOUMARIN | IC50=1ug/ml | * |
(-)-CAPAURINE | IC50=1910-4340 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BETULINIC-ACID | IC50=19-26 ug/ml | * |
EVODULONE | IC50=18.27 ug/mL) | * |
DIHYDROBRACHY-CALYXOLIDE | IC50=17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-ISOLAURELINE | IC50=1610-2560 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-E | IC50=16-17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-E/F | IC50=16-17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-F | IC50=16-17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
MUZANZAGENIN | IC50=16-163 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROBERTSONINE-A | IC50=15.9->23.7 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
COCSULINE | IC50=15.56 ug/mL | * |
BONASPECTIN-G/H | IC50=15-17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-H | IC50=15-17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-G | IC50=15-17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PRIEURIANIN | IC50=14.08 ug/mL) | * |
ISOSTRYCHNINE | IC50=14->20 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VINCAMAJINE | IC50=138 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALSTOUMERINE | IC50=13.1 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DIGITOLUTEIN | IC50=13-83 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-ANONAINE | IC50=1290-1900 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NORFLUOROCURARINE | IC50=129 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-DICENTRINE | IC50=1260-2550 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
8-EPIXANTHIN | IC50=125 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALSTOPHYLLINE | IC50=12.7-82.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
FAGARAMIDE | IC50=12.3 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NYASOL | IC50=12 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AZADIRONE | IC50=12 ug/ml | Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982. |
QUINICINE | IC50=11.2 ug/ml | Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. |
BRUCEINE-A | IC50=11 ng/ml | Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. |
BRUCEINE-B | IC50=11 ng/ml | Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. |
PATCHOULENE | IC50=108 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PIQUEROL-A | IC50=100 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ISOTETRANDRINE | IC50=100 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VILLALSTONINE-NB-OXIDE | IC50=10.7 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GALLAGIC-ACID | IC50=10.6-10.9 ug | * |
GOSSYPOL | IC50=10 uM | * |
1-DEACETYLKHIVORIN | IC50=10 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NIMBOLIDE | IC50=1.74 ug/mL | * |
O-METHYLEXOSTEMIN | IC50=1.6-3.6 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
COWAXANTHONE | IC50=1.5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PHAEANTHINE | IC50=1.43 ug/ml (1/10 x chloroquine) | * |
NARDISINONE | IC50=1.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NARDOPEROXIDE | IC50=1.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ARTEMISININ | IC50=1.4 nM or 0.0014 uM (ED95=1,000 mg/man/day) | * |
CORONARIDINE | IC50=1.3-2.2 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANNONACIN | IC50=1.3-1.5 ppm | Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238. |
EURYCOMANOL | IC50=1.2-4.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
EURYCOMANONE | IC50=1.2-4.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALSTOMACROLINE | IC50=1.1-10.2 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GONIOTHALAMICIN | IC50=1.1-1.6 ppm | Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238. |
ALSTOMACROPHYLLINE | IC50=1.1 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GILLETINE | IC50=1.1 ug/ml (ca 1/8 x chloroquine) | * |
BRUCEAJAVIN-A | IC50=1.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
KORUNDAMINE-A | IC50=1.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEAJAVIN-B | IC50=1.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
QUERCETIN | IC50=1-6.4 ug/ml | Medicinal and Poisonous Plants of the Tropics. Leeuwenberg, A.J.M., ed. Pudoc, Wageningen. 1987. |
18-HYDROXYSUNGUCINE | IC50=1-4 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-C | IC50=1-3 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-TETRAHYDROSTEPHABINE | IC50=1,940-2,230 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-ROEMEROLINE | IC50=1,780-3,150 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PHEANTHINE | IC50=1,400 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
RUGOSAL-A | IC50=1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BONASPECTIN-C-4''-O-GLUCOSIDE | IC50=1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ALPHA-PEROXYACHIFOLIDE | IC50=1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
1,2-DI-O-ACETYLCORINE | IC50=1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
1-BETA-HYDROPEROXYISOBILIN | IC50=1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
O-METHYLMACRALSTONINE | IC50=0.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NEUROLENIN-A | IC50=0.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GALIPININE | IC50=0.9 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BENZOISOQUINOLONE-5-10-DIONE | IC50=0.84 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CRYPTOHEPINE | IC50=0.8-1.2 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ISOCRYPTOLEPINE | IC50=0.8 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEANTIN | IC50=0.8 ng/ml | * |
NIMBININ | IC50=0.77 ug/ml | * |
CEDRELONE | IC50=0.77 ug/ml | Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982. |
EPOXYADADIRADONE | IC50=0.77 ug/ml | Zeits. Lebensmitt. Unters. & Forsch. Acta Botanica Sinica, 174(3):211. 1982. |
7-O-DEMETHYLTETRANDRINE | IC50=0.74 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GEDUNIN | IC50=0.7-8.5 ug/ml | * |
(+)-AROMOLINE | IC50=0.67 ug/ml (ca 1/5 chloroquine) | * |
AROMOLINE | IC50=0.67 ug/ml (ca 1/5 chloroquine) | * |
TILIACORINE | IC50=0.67 ug/ml | * |
ANCISTROLIKOKINE-C | IC50=0.62-0.92 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ROEMREFRIDINE | IC50=0.6-0.7 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NEUROLENIN-B | IC50=0.6 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NEUROLENIN-C/D | IC50=0.6 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NOR-TILIACORINE-A | IC50=0.56 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
OBAMEGINE | IC50=0.51 ug/ml (1/4 x chloroquine) | * |
13-BETA-D-DIHYDROEURYCOMANOL | IC50=0.5-2.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VOACHALOTINE | IC50=0.5-0.8 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
OPHIOBOLIN-A | IC50=0.5-0.6 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEINE-C | IC50=0.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ELLAGIC-ACID | IC50=0.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
THALIFABERINE | IC50=0.44-5.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
JATRORRHIZINE | IC50=0.42-1.61 ug/ml | * |
MACROCARPAMINE | IC50=0.4-32.6 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
EURYCOMANOL-2-O-BETA-D-GLUCOPYRANOSIDE | IC50=0.4-3.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3-O-BENZOYLHOSLOPPONE | IC50=0.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VILLALSTONINE | IC50=0.3-2.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
7-METHOXY-BETA-CARBOLINE-1-PROPIONIC-ACID | IC50=0.3-2.9 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ISOSUNGUCINE | IC50=0.3-1.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GEDUNIN | IC50=0.3-1 uM | * |
LYCORINE | IC50=0.3-0.7 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
VOACANGINE | IC50=0.3-0.5 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PLUMBAGIN | IC50=0.3 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
OXYACANTHINE | IC50=0.3 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TRICHIRUBRINE-A | IC50=0.3 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-1,2-DEHYDROTELOBINE | IC50=0.26-0.31 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
6-ALPHA-TIGLOYLOXYGLAUCARUBOL | IC50=0.257 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CONOPHARYNGINE | IC50=0.24-0.29 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CEDRONIN | IC50=0.23-0.25 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-OBABERINE | IC50=0.22-0.23 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROLIKOKINE-B | IC50=0.21-0.54 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
10'-HYDROXYUSAMBARENSINE | IC50=0.2-0.5 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
KORUPENSAMINE-B | IC50=0.2-0.4 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DEHATRINE | IC50=0.2 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
7-EPIDIONCHOPHYLLINE-A | IC50=0.2 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PRISTIMERIN | IC50=0.19-28 ug/ml | * |
14-HYDROXYCHAPARRINONE | IC50=0.188 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CELASTROL | IC50=0.181-0.254 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
QUININE | IC50=0.18 ug/ml | Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. |
PLUMBAGIN | IC50=0.178-0.189 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-TETRANDRINE | IC50=0.16-0.18 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PYCNAMINE | IC50=0.15 ug/mL (ca 1 x chloroquine) | * |
(+)-CEPHARANTHINE | IC50=0.14-0.30 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ANCISTROLIKOKINE-A | IC50=0.14-0.19 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AUGUSTINE | IC50=0.14-0.18 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-STEPHIBABERINE | IC50=0.13-0.31 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
THALIFABERIDINE | IC50=0.12-0.88 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
18-HYDROXYISOSUNGUCINE | IC50=0.1-0.9 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CLAUSARIN | IC50=0.1-0.7 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
PSYCHOTRINE | IC50=0.1-0.4 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
COSTARICINE | IC50=0.1-0.3 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CRYPTOLEPINE | IC50=0.1-0.2 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
HYDRANTHINE-A | IC50=0.1 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3-METHOXYSAMPANGINE | IC50=0.09-0.28 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-2-N-METHYLTELOBINE | IC50=0.09-0.26 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
28-NOR-IGOIGUESTERIN-17-CARBALDEHYDE | IC50=0.080-0.094 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AKUAMMIDINE | IC50=0.08-0.9 ug/ml | Iwu, M.M. 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, FL 435 pp. |
SAMADERINE-Z-CHAPARRINONE | IC50=0.071 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
SAMADERINE-B-CHAPARRINONE | IC50=0.071 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-2-NOR-THALRUGOSINE | IC50=0.07-0.13 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ISOTETRANDRINE | IC50=0.07 ug/ml (2 x chloroquine) | * |
(+)-THALRUGOSINE | IC50=0.06-0.23 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-DEPHNANDRINE | IC50=0.06-0.22 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
LIMACINE | IC50=0.05-0.79 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3-HYDROXY-6'-DESMETHYL-9-O-METHYL-THALIFABORAMINE | IC50=0.05-0.24 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
THALIFASINE | IC50=0.05-0.24 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-ISOTETRANDRINE | IC50=0.05-0.17 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-2-NOR-CEPHARANTHINE | IC50=0.05-0.13 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-2-NOR-OBABERINE | IC50=0.05-0.09 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-2-NOR-ISOTETRANDRINE | IC50=0.05-0.07 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
15-DESACETYLUNDULATONE | IC50=0.047 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEINE-D | IC50=0.037-0.5 uM | * |
CHAPARRINONE | IC50=0.037 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DIONCHOPELTINE-A | IC50=0.033 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CRYPTOLEPINE | IC50=0.031 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(-)-CYCLEAPELTINE | IC50=0.03-0.04 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
17-METHOXY-28-NORISOIGUESTERIN | IC50=0.028-0.37 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
AILANTHINONE | IC50=0.025 uM | * |
ISOIGUESTEROL | IC50=0.023-0.54 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEINE-B | IC50=0.023-0.5 uM | * |
BRUCEINE-A | IC50=0.021-0.5 uM | * |
SAMADERINE-E-CHAPARRINONE | IC50=0.021 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DIONCHOPHYLLINE-B | IC50=0.021 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
KORUPENSAMINE-A | IC50=0.02-0.6 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
(+)-HOMOAROMOLINE | IC50=0.02-0.29 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
SAMADERINE-X-CHAPARRINONE | IC50=0.015 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
DIONCHOPHYLLINE-C | IC50=0.014 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
CEPHAELINE | IC50=0.011-0.027 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3-HYDROXY-THALIFABORAMINE | IC50=0.01-0.18 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
6'-DESMETHYL-THALIFABORAMINE | IC50=0.01-0.15 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
SARACHINE | IC50=0.01-0.07 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
3',4'-DIHYDROUSAMBARENSINE | IC50=0.01 ug/ml | * |
BRUCEINE-C | IC50=0.009 uM | * |
FAGARONINE | IC50=0.009 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
TUBULOSINE | IC50=0.006-0.011 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUSATOL | IC50=0.006 uM | * |
BRUCEINE-A | IC50=0.005-0.011 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEINE-C | IC50=0.005-0.011 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEINE-B | IC50=0.005-0.011 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GUTOLACTONE | IC50=0.004 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
BRUCEANTINOL | IC50=0.003 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
ISOFEBRIFUGINE | IC50=0.002-0.003 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
FEBRIFUGINE | IC50=0.001-0.07 uM | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
SIMALIKALACTONE-D | IC50=0.001-0.002 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
NIMBOLIDE | IC50=0.001 ug/ml | Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp. |
GLAUCARUBINONE | ED=0.006 ug/ml | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
ARTEMISININ | ED95=1,000 mg/man/day | Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. |
ARTEMISININ | ED50=90 mg/kg orl mus | Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. |
SERGEOLIDE | ED50=0.26 mg/kg day | Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp. |
CARYOPHYLLENE-ALPHA-OXIDE | EC50=>3-100 uM | * |
4,7-DIMETHYL-1-TETRALONE | EC50=>3-100 uM | * |
EXIGUAFLAVONE-B | EC50=7 ug/ml | Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147. |
EXIGUAFLAVONE-A | EC50=4.6 ug/ml | Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147. |
UVARETIN | EC50=4.5 ug/ml | Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147. |
DIUVERETIN | EC50=4.2 ug/ml | Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147. |
2-(2,4-DIHYDROXYPHENYL)-5,6-METHYLENEDIOXYBENZOFURAN | EC50=27 ug/ml | Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147. |
MAACKIAIN | EC50=10 ug/ml | Chanphen, R., Thebtaranonth, Y., Wanauppathamkul, S., and Yuthavong, Y. 1998. Antimalarial Principles from Artemisia indica. J. Nat. Prod., 61 (9):1146-1147. |
TOTAQUINE | 600 mg/3x/day/man | Martindale's 29th |
COLCHICINE | 500 ug/10x/day/man | Martindale's 28th |
BERBERINE | 50 uM | * |
BERBERASTINE | 50 uM | * |
ATALAPHILLININE | 50 mg/kg/day ipr mus | * |
ATAPHILLININE | 50 mg/kg (ipr mus) | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
AJOENE | 50 mg/kg | * |
BETA-SELININE-HYDROPEROXIDE | 5.6 ug/ml | * |
ALPHA-CYPERONE | 5.5 ug/ml | * |
SECURININE | 5.4 ug/ml | * |
PUNICALAGIN | 2-8 ug/ml | * |
QUININE-SULFATE | 2,000 mg/man/day | Martindale's 28th |
CINCHONIDINE | 150-500 mg/man/4 x day | * |
GAMMA-DICHROINE | 100 x quinine | Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. |
QUINIDINE | 10 mg/kg/orl/man/8 hrs | Martindale's 29th |
ECHITAMINE | 1.6 mg/kg | * |
COLUMBAMINE | 0.72 ug/ml | * |
BERBERASTINE | 0.14-0.36 ug/ml | * |
BERBERINE | 0.14-0.36 ug/ml | * |
ASCARIDOLE | 0.05-0.1 uM | * |
DEHYDROBRUCEINE | 0.046 ug/ml | * |
HYDROQUINONE | -- | * |
ARTEMISINE | -- | * |
OSTRUTHIN | -- | * |
BEBEERINE | -- | Merck 11th Edition |
YINGHAOSU-A | -- | * |
AILANTHONE | -- | Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. |
APIOLE | -- | * |
SWERCHIN | -- | Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989. |
GENTIOPICRIN | -- | Merck 11th Edition |
HARMINE | -- | UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp. |
ARTEANNUIN | -- | * |
PHLORIDZIN | -- | * |
NORTILIACORININE-A | -- | * |
QUINOLINE | -- | Merck 11th Edition |
LAPINONE | -- | * |
GLAUCARUBIN | -- | * |
HYDROQUINIDINE | -- | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
OSTHOLE | -- | * |
FEBRIFUGINE | -- | Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart. |
EMETINE | -- | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
AKUAMMIGINE | -- | * |
PALMATINE | -- | * |
BRUCEINE | -- | * |
CURINE | -- | * |
YADANZIOLIDE-A | -- | * |
LICOCHALCONE-A | -- | * |
ARTESUNATE | -- | * |
PHLORIZIN | -- | * |
DICHROINE | -- | * |
HARMALINE | -- | UNESCO. 1960. Medicinal Plants of the Arid Zones. eds.(botany) I.C. Chopra, B.K. Abrol and K.L. Hands; eds (pharmacology), R. Paris and G. Dillemann UNESCO, Place de Fontenoy, Paris 7E. 96 pp. |
ARTARINE | -- | * |
BETA-DICHROINE | -- | Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. |
EURYCOMALACTONE | -- | * |
LAPACHOL | -- | * |
DIHYDROQUINIDINE | -- | * |
HOMOHARRINGTONINE | -- | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
ARTEMETHER | -- | Merck 11th Edition |
BONDUCIN | -- | * |
ROBUSTANOL | -- | * |
ARTEMETIN | (Synergic w artemisinin) IC50=26 uM | * |
CASTICIN | (Synergic w artemisinin) | * |
GLYCOCITRINE-I | (= chloroquine) | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
GLYCOBISMINE-A | (= chloroquine) | Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp. |
AKUAMMINE | (1/500th chloroquine) 1 mg/kg | Neuwinger, H. D. 1996. African Ethnobotany - Poisons and Drugs. Chapman & Hall, New York. 941 pp. |