Chemical Dosage References
EUGENOLIC>97=1,000 uM*
APIGENINIC>65=1,000 uM*
ROSMARINIC-ACIDIC>58=1,000 uM*
CIRSIMARITINIC>50=1,000 uM*
ISOTHYMONINIC>37=1,000 uM*
CIRSILINEOLIC>37=1,000 uM*
BETA-CAROTENEIC82=50 ug/ml*
PINOSTROBINIC7=100 ug/ml*
CYANIDIN-3-O-GLUCOSIDEIC59=100 ug/ml*
APIGENINIC50=<15 uM*
PTEROSTILBENEIC50=84 uM*
MYRICETIN-3-O-BETA-D-GLUCURONIDEIC50=8 uM/Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
(+)-CATECHINIC50=546-5,910 uM (cf indomethacin IC50=1 uM)*
AR-TURMERONEIC50=5.6 ug/ml*
OLEANOLIC-ACIDIC50=295 uM/*
CINNAMALDEHYDEIC50=245 uM*
URSOLIC-ACIDIC50=130 uM/*
EUGENOLIC50=129 uM*
BETA-TURMERONEIC50=1.6 ug/ml*
ANTHOCYANINSIC47=125 ug/ml*
CAFFEIC-ACIDIC32=100 uM*
LAURIC-ACIDIC20=100*
CINNAMIC-ACID-BORNYL-ESTERIC19=100 ug/ml*
3,4-METHYLENE-DIOXYCINNAMIC-ACID-BORNYL-ESTERIC18=100 ug/ml*
FLAVOKAWAIN-BIC16=100 ug/ml*
RESVERATROL>2.5->22.5 uM*
QUERCETIN<40 uM*
APIGENIN<40 uM*
RESVERATROL50 uM/*
RESVERATROL30 uM/Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
TRANS-RESVERATROL20 uM/Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
RUTAECARPINE2.5 ug/ml (strong activity)Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
EVODIAMINE2.5 ug/mlKang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
EVODOL2.5 ug/mlKang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
BAICALEIN100 ug/ml*
BERBERASTINE100 ug/ml*
BERBERINE100 ug/ml*
CURCUMIN10-20 uM*
EICOSAPENTAENOIC-ACID1 uM*
AJOENE--*
PARTHENOLIDE--Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
SALICYLIC-ACID--Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
BOSWELLIC-ACID--*
MELATONIN--Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
AIPHANOL--*
UROLITHIN-A--*
HUMULONE--Yamamoto, Wang, et al. 2000. Federation of European Biochemical Societies. (per e-mail with Tom Newmark)
OLEANOLIC-ACID--Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
PUNICIC-ACID--*
KAEMPFEROL--*
ALPHA-BOSWELLIC-ACID--*
EMODIN--*