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All Chemicals: 80
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Chemical Dosage References
(+)-PURPURIN ED50=5.6 uM*
(+)-TEPHROPURPURIN IC50 13.4 uM*
(+)-TEPHROPURPURIN ED50=0.15 uM*
(-)-3-HYDROXY-4-METHOXY-8,9-METHYLENEDIOXYPTEROCARPAN IC50=>63.7 uM*
(-)-MAACKIAIN ED50=8.8 uM*
(-)-MEDICARPIN ED50=13.7 uM*
(1'S)-1'-ACETOXYCHAVICOL-ACETATE --*
24,25-DIHYDROWITHANOLIDE-D ED50=0.7 uMKennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
3-METHOXY-2,3-DIHYDROWITHAPHYSACARPIN ED50=7.8 uMKennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
4',7-DIHYDROXY-3',5'-DIMETHOXYISOFLAVONE ED50=17.2 uM*
4-HYDROXY-GLUCOBRASSICIN 100 uMFahey, J. W., Zhang, Y., Talalay, P. 1997. Broccoli Sprouts: An Exceptionally Rich Source of Inducers of Enzymes that Protects Against Chemical Carcinogens. Proc. Nat. Acad. Sci., 94: 10367-10372.
6-METHYL-SULFINYL-HEXYL-ISOTHIOCYANATE --Fuke, Y., Haga, Y., Ono, H., Nomura, T., Ryoyama, K. 1998. Anti-Carcinogenic Activity of 6-methylsulfinylhexyl isothiocyanate, an Active Anti-Proliferative Principle of Wasabi (Eutrema wasabi Maxim.). Cytotechnology, 25: 197-203.
7,4'-DIHYDROXY-3',5'-DIMETHOXYISOFLAVONE IC50>63.7 uM*
ALYSSIN 0.95 uM*
APIGENIN 20 uMUda, Y., Price, K. R., Williamson, G., Rhodes, M. J. C. 1997. Induction of the Anticarcinogenic Marker Enzyme, Quinone Reductase, in Murine Hepatoma Cells In Vitro by Flavonoids. Cancer Lett., 120 (2): 213-216.
AURAPTENE 400 mg/kg igs ratTanaka,T. et al.1998.Citrus Auraptene Exerts Dose-Dependent Chemopreventive Activity in Rat Large Bowel Tumorigenesis:The Inhibition Correlates with Suppression of Cell Proliferation & Lipid Peroxidation & with Induction of Phase II-. Cancer Res.58:2550.
AURAPTENE 100 ppm*
BAICALIN --*
BERTEROIN 1.7 uMZhang, Y., Talalay, P., Cho, C. G., Posner, G. H. 1992. A Major Inducer of Anticarcinogenic Protective Enzymes from Broccoli: Isolation and Elucidation of Structure. Proc. Nat. Acad. Sci., 89: 2399-2403.
BIS-DEMETHOXYCURCUMIN 11.9 uMSingletary, K., et al. 1998. Effect of the Beta-Diketones Diferoloylmethane (Curcumin) and Dibenzoylmethane on Rat Mammary DNA Adducts and Tumors Induced by 7,12-dimethylbenz(A)anthracene. Carcinogenesis, 19(6): 1039-1043.
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.