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Chemical Dosage References
MEDICARPIN IC50>74.8 uM*
7,4'-DIHYDROXY-3',5'-DIMETHOXYISOFLAVONE IC50>63.7 uM*
PURPURIN IC50>50.7 uM*
LANCEOLATIN-B IC50=>76.3 uM*
(-)-3-HYDROXY-4-METHOXY-8,9-METHYLENEDIOXYPTEROCARPAN IC50=>63.7 uM*
L-MAACKIAIN IC50=>13.4 uM*
SULFORAPHANE IC50=5-0.03 ug/mlLee, S. K., Song, Y., Mata-Greenwood, E., Kelloff, G. J., Steele, V. E., Pezzuto, J. M. 1999. Modulation of in vitro Biomarkers of the Carcinogenic Process by Chemopreventive Agents. Anticancer Res., 19: 35-44.
GENISTEIN IC50=4.6 ug/ml*
PONGAMOL IC50=18.7 uM*
SULFORAPHANE IC50=11 uM*
(+)-TEPHROPURPURIN IC50 13.4 uM*
(-)-MAACKIAIN ED50=8.8 uM*
3-METHOXY-2,3-DIHYDROWITHAPHYSACARPIN ED50=7.8 uMKennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
PONGAMOL ED50=6.1 uM*
(+)-PURPURIN ED50=5.6 uM*
4',7-DIHYDROXY-3',5'-DIMETHOXYISOFLAVONE ED50=17.2 uM*
(-)-MEDICARPIN ED50=13.7 uM*
24,25-DIHYDROWITHANOLIDE-D ED50=0.7 uMKennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
WITHAPHYSACARPIN ED50=0.43 uMKennelly, E. J., Gerhauser, C., Song, L. L., Graham, J. G., Beecher, C. W. W., Pezzuto, J. M., Kinghorn, A. D. 1997. Induction of Quinone Reductase by Withanolides Isolated from Physalis philadelphica (Tomatillos). J. Agr. & Food Chem., 45(10): 3771-3777.
SULPHORAPHANE ED50=0.43 uM*
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.