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All Chemicals: 52
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Chemical Dosage References
CIRSIMARITIN IC>50=1,000 uM*
CURCUMIN 10-20 uM*
CYANIDIN-3-O-GLUCOSIDE IC59=100 ug/ml*
EICOSAPENTAENOIC-ACID 1 uM*
EMODIN --*
EUGENOL IC50=129 uM*
EUGENOL IC>97=1,000 uM*
EVODIAMINE 2.5 ug/mlKang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
EVODOL 2.5 ug/mlKang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
FLAVOKAWAIN-B IC16=100 ug/ml*
HUMULONE --Yamamoto, Wang, et al. 2000. Federation of European Biochemical Societies. (per e-mail with Tom Newmark)
ISOTHYMONIN IC>37=1,000 uM*
KAEMPFEROL --*
LAURIC-ACID IC20=100*
MELATONIN --Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=8 uM/Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
OLEANOLIC-ACID --Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
OLEANOLIC-ACID IC50=295 uM/*
PARTHENOLIDE --Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
PINOSTROBIN IC7=100 ug/ml*
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.