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All Chemicals: 52
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Chemical Dosage References
URSOLIC-ACID IC50=130 uM/*
UROLITHIN-A --*
TRANS-RESVERATROL 20 uM/Jang, M., Pezzuto, J. M. 1999. Cancer Chemorpreventive Activity of Resveratrol. Drugs Exp. Clin. Res., 25(2/3): 65-77.
SALICYLIC-ACID --Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
RUTAECARPINE 2.5 ug/ml (strong activity)Kang, S. S., Kim, J. S., Son, K. H., Kim, H. P., Chang, H. W. 1999. Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa. Nat. Prod. Sci., 5(2): 65-69.
ROSMARINIC-ACID IC>58=1,000 uM*
RESVERATROL 50 uM/*
RESVERATROL >2.5->22.5 uM*
RESVERATROL 30 uM/Subbaramaiah, K., Michaluart, P., Chung, W. J., Dannenberg, A. J. 1998. Resveratrol Inhibits the Expression of Cyclooxygenase-2 in Human Mammary and Oral Epithelial Cells. Pharm. Biol. Suppl., 36: 35-43.
QUERCETIN <40 uM*
PUNICIC-ACID --*
PTEROSTILBENE IC50=84 uM*
PINOSTROBIN IC7=100 ug/ml*
PARTHENOLIDE --Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
OLEANOLIC-ACID IC50=295 uM/*
OLEANOLIC-ACID --Ringbom, T., Seguar, L., Noreen, Y., Perera, P., Bohlin, L. 1998. Ursolic Acid from Plantago major, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis. J. Nat. Prod., 61(10): 1212-1215.
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=8 uM/Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
MELATONIN --Newmark, T. M. and Schulick, P. 2000. Herbal Cox-2 Inhibition - Nature's Challenge to Arthritis, Cancer & Alzheimer's Disease. Hohm Press, Prescott AZ.
LAURIC-ACID IC20=100*
KAEMPFEROL --*
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.