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Chemical Dosage References
VERBENALIN --Williamson, E. M. and Evans, F. J., Potter's New Cyclopaedia of Botanical Drugs and Preparations, Revised Ed., Saffron Walden, the C. W. Daniel Co., Ltd., Essex UK, 362 pp, 1988, reprint 1989.
SORBITOL 30-50 g/man/dayMartindale's 28th
SENNOSIDE-F ED50=16.1 mg/kg orl mus*
SENNOSIDE-E ED50=15.8 mg/kg orl mus*
SENNOSIDE-D ED50=15.8 mg/kg orl mus*
SENNOSIDE-C ED50=13.3 mg/kg orl mus*
SENNOSIDE-B ED50=13.9 mg/kg orl mus*
SENNOSIDE-A ED50=13.5 mg/kg orl mus*
RHEINOSIDE ED50=15 mg/kg orl mus*
RHEIN ED50=97.5 mg/kg orl mus*
PODOPHYLLIN --Martindale's 29th
PHYSCION ED50=>500 mg/kg orl mus*
PHORBOL --Cooper-Driver, G. A., Chemical substances in plants toxic to animals, pp. 213-47 in Rechcigl, M., Jr., ed. CRC Handbook of Naturally Occurring Food Toxicants, CRC Press, Boca Raton, 1983, 339 pp.
MESACONITINE 0.3-0.5 mg/kg*
*Unless otherwise noted all references are to Duke, James A. 1992. Handbook of phytochemical constituents of GRAS herbs and other economic plants. Boca Raton, FL. CRC Press.