Chemical TETRAMETHYL-PYRAZINE | Dr. Duke's Phytochemical and Ethnobotanical Databases

Chemical ID

TETRAMETHYLPYRAZINE

Ubiquitous

List of known dosages
Dosage	Reference
LD50=416 (ivn mus)
LD50=70 (ipr mus)
LD50=239 mg/kg (ivn mus)	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Antiaggregant	not available	Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Antianginal	ED88=100-200 mg man	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antiasthmatic	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antibacterial	not available	Recio, M. C., Rios, J. L., and Villar, A., A review of some antimicrobial compounds isolated from medicinal plants reported in the literature 1978-1988, Phytotherapy Research, 3(4), 1989, 117-125.
Anticholinergic	not available	Duke, 1992 *
Antidysmenorrheic	not available	Duke, 1992 *
Antiembolic	not available	Duke, 1992 *
Antihistaminic	1 mg/kg	Duke, 1992 *
Antihypertensive	not available	Duke, 1992 *
Antiischemic	ED85=40-80 mg man	Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp.
Antimetastatic	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Antispasmodic	not available	Duke, 1992 *
Arteriodilator	not available	Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Calcium-Antagonist	not available	Leung, A. Y. and Foster, S. 1995. Encyclopedia of Common Natural Ingredients 2nd Ed. John Wiley & Sons, New York. 649 pp.
Cardiac	not available	Ozaki, Y. and Ma, J-P. 1989. Inhibitory Effects of Tetramethylpyrazine and Ferulic Acid on Spontaneous Movement of Rat Uterus in Situ. Chem. Pharm. Bull. 38(6): 1620-1623, 1990.
Cardiotonic	not available	Duke, 1992 *
Diuretic	not available	Duke, 1992 *
Hypotensive	20-May	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
Schistosomicide	not available	Duke, 1992 *

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Camellia sinensis	Leaf	not available	not available	not available	Jim Duke's personal files.
Capsicum annuum	Fruit	not available	not available	not available	Duke, 1992 *
Ephedra sinica	Shoot	not available	39.0	not available	Duke, 1992 *
Glycine max	Seed	not available	not available	not available	Chemical Constituents of Oriental Herbs (3 diff. books)
Glycyrrhiza glabra	Root	not available	not available	not available	Duke, 1992 *
Rheum palmatum	Rhizome	not available	1.0	not available	Duke, 1992 *