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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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MAKALUVAMINE-E

Chemical ID
MAKALUVAMINEE
Ubiquitous
No
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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Topoisomerase-II-Inhibitor IC50=310 uM Radisky, D. C., Radisky, E. S., Barrows, L. R., Copp, B. R., Kramer, R. A., Ireland, C. M. 1993. Novel Cytotoxic Topoisomerase II Inhibiting Pyrroloiminoquinones From Fijian Sponges of the Genus Zyzzya. J Amer Chem Soc, 115: 1632-1638.
Topoisomerase-II-Inhibitor MIC=133 ug/ml Barrows, L. R., Radisky, D. C., Copp, B. R., Swaffar, D. S., Kramer, R. A., Warters, R. L., Ireland, C. M. 1993. Makaluvamines, Marine Natural Products are Active Anti-Cancer Agents and DNA Topo II Inhibitors. Anticancer Drug Design, 8: 333-347.