Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical MAKALUVAMINE-A

Chemical ID
MAKALUVAMINEA
Ubiquitous
No

Select a Results View:

Download these results as:
CSV
XLSX
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Topoisomerase-II-Inhibitor IC50=41 uM Radisky, D. C., Radisky, E. S., Barrows, L. R., Copp, B. R., Kramer, R. A., Ireland, C. M. 1993. Novel Cytotoxic Topoisomerase II Inhibiting Pyrroloiminoquinones From Fijian Sponges of the Genus Zyzzya. J Amer Chem Soc, 115: 1632-1638.
Topoisomerase-II-Inhibitor MIC=13 ug/ml Barrows, L. R., Radisky, D. C., Copp, B. R., Swaffar, D. S., Kramer, R. A., Warters, R. L., Ireland, C. M. 1993. Makaluvamines, Marine Natural Products are Active Anti-Cancer Agents and DNA Topo II Inhibitors. Anticancer Drug Design, 8: 333-347.