Chemical ID
HARRINGTONINE
Ubiquitous
No
Dosage | Reference |
---|---|
LD50=4.3 mg/kg (ipr mus) | Huang, K. C. 1993. The Pharmacology of Chinese Herbs. CRC Press, Boca Raton, FL 388 pp. |
Activity | Dosage | Reference |
---|---|---|
Anticarcinomic | 0.5-1 ppm | Duke, 1992 * |
Antileukemic | (2 ppm), 2-4 mg | Martindale's 29th |
Antimelanomic | ED50=0.077 ug/ml | J. Ethnopharmacology, 32: 117. |
Antisarcomic | ED50=0.01 ug/ml | J. Ethnopharmacology, 32: 117. |
Antitumor (Breast) | ED50=0.017 ug/ml | J. Ethnopharmacology, 32: 117. |
Antitumor (Colon) | ED50=0.014 ug/ml | J. Ethnopharmacology, 32: 117. |
Antitumor (Lung) | ED50=0.036 ug/ml | J. Ethnopharmacology, 32: 117. |
DNA-Synthesis-Inhibitor | not available | Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp. |
Plant Name | Plant Part | Low Parts Per Million | High Parts Per Million | Standard Deviation | Reference |
---|---|---|---|---|---|
Cephalotaxus fortunei | Stem | not available | not available | not available | Duke, 1992 * |
Cephalotaxus harringtonii | Tissue Culture | 0.0 | 0.2 | not available | Duke, 1992 * |
Cephalotaxus harringtonii | Fruit | not available | 500.0 | not available | Duke, 1992 * |