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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. DEOXYPODOPHYLLOTOXIN

DEOXYPODOPHYLLOTOXIN

Chemical ID
DEOXYPODOPHYLLOTOXIN
Ubiquitous
No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Antiherpetic 414 ppb Bedows, E. and Hatfield, G.M. An Investigation of the Antiviral Activity of Podophyllum peltatum. J. Nat. Prod. 45: 725.
Antiherpetic IC50=0.025 uM *
Antileukemic 4.7 ppb *
Antimitotic Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antistomatitic IC50=0.025 uM *
Antitumor Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Antiviral IC50=0.025 uM *
Antiviral MIC=38 nM *
Artemicide 150 ppb *
Cytotoxic 4-400 ppm Wagner & Wolff, eds. 1977. New Natural Products (RS164. I56. 176)
Herbicide *
Insecticide *
Topoisomerase-II-Inhibitor IC50=186.5 uM Terada, T., et al. 1992. Antitumor Agents. I. DNA Topoisomerase II Inhibitory Activity and the Structural Relationship of Podophyllotoxin Derivatives as Antitumor Agents. Chem Pharm Bull, 40: 2720-2727.
Topoisomerase-II-Inhibitor 10 ug/ml Figgitt, D. P., Denyer, S. P., Dewick, P. M., Jaackson, D. E., Williams, P. Differential Sensitivity of Fungal Topoisomerases to Podophyllotoxin Derivatives. J Pharm Pharmacol Suppl, 41: 44pp.
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Anthriscus cerefolium Plant *
Juniperus communis Fruit *