Chemical COUMARIN | Dr. Duke's Phytochemical and Ethnobotanical Databases

Dr. Duke's Phytochemical and Ethnobotanical Databases

U.S. Department of Agriculture

Chemical ID

COUMARIN

Ubiquitous

No

List of known dosages
Dosage	Reference
LD50=202 (orl gpg)	Merck 11th Edition
LD50=293 (orl rat)	CRC Handbook of Medicinal Herbs and/or CRC Handbook of Proximate Analyses, Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=680 (orl rat)	Merck 11th Edition
LD50=720 (orl rat)

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity	Dosage	Reference
Hepatotoxic	100 mg/kg dog	Duke, 1992 *
Hepatotoxic	0.8-1.71 mM/kg orl rat	Duke, 1992 *
Hypnotic	not available	Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.
Hypoglycemic	250-1,000 mg/kg orl	Economic & Medicinal Plant Research, 6: 165
Immunostimulant	not available	Duke, 1992 *
Juvabional	not available	Jacobson, M., Glossary of Plant-Derived Insect Deterrents, CRC Press, Inc., Boca Raton, FL, 213 p, 1990.
Larvistat	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Lymphocytogenic	100 mg/day	Gawron, A., Gorski, G., Glowniak*, K. 1989. Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment. J. Pharm. Pharmacol. 42: 194-195, 1990.
Lymphokinetic	not available	Duke, 1992 *
Narcotic	not available	Duke, 1992 *
Ovicide	not available	Duke, 1992 *
Pesticide	not available	Duke, 1992 *
Phagocytotic	not available	Planta Medica, 56(6): 671, 1990.
Piscicide	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Respirodepressant	not available	Duke, 1992 *
Rodenticide	not available	Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
Sedative	not available	Schultes, R.E. De Plantis Toxicariis e Mundo Novo Tropicale Commentationes XXXVI. Justicia (Acanthaceae) as a Source of an Hallucinogenic Snuff. Economic Botany 44(1): 61-70, 1990.

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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name	Plant Part	Low Parts Per Million	High Parts Per Million	Standard Deviation	Reference
Vitis vinifera	Fruit	not available	not available	not available	List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Zea mays	Leaf	not available	not available	not available	Duke, J. A. Writeups or information summaries on approximately 2,000 economic plants, USDA, ARS, Beltsville, MD 20705.
Zizyphus jujuba	Leaf	not available	3000.0	-0.5	Duke, 1992 *