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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Chemical 4'-DEMETHYLPODOPHYLLOTOXIN

Chemical ID
4DEMETHYLPODOPHYLLOTOXIN
Ubiquitous
No

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List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Topoisomerase-II-Inhibitor 100 uM Lee, K. H., et al. 1989. Antitumor Agents. 107. New Cytotoxic 4-alkylamino Analogues of 4'-demethyl-epipodophyllotoxin as Inhibitors of Human DNA Topoisomerase II. J Natural Products, 52: 606-613.
Topoisomerase-II-Inhibitor 10 ug/ml Figgitt, D. P., Denyer, S. P., Dewick, P. M., Jaackson, D. E., Williams, P. Differential Sensitivity of Fungal Topoisomerases to Podophyllotoxin Derivatives. J Pharm Pharmacol Suppl, 41: 44pp.
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List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Podophyllum hexandrum Rhizome ANON. 1948-1976. The Wealth of India raw materials. Publications and Information Directorate, CSIR, New Delhi. 11 volumes.
Podophyllum peltatum Rhizome *