An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Chemical 1,8-CINEOLE

Chemical ID
18CINEOLE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,480 (orl rat) Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=3,480 mg/kg
LD50=>5,000 (dml rbt)
LD100=1,000 ug/ml
LD50=100 mg/kg (ims mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Expectorant not available Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 1-200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide not available Duke, 1992 *
Gastroprotective not available Duke, 1992 *
Gram(+)icide not available Duke, 1992 *
Gram(-)icide not available Duke, 1992 *
Hepatotonic not available Duke, 1992 *
Herbicide IC50=78 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypotensive not available Duke, 1992 *
Inflammatory inj Duke, 1992 *
Insectifuge not available Duke, 1992 *
Irritant not available Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant not available Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide not available Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Neurotoxic not available Duke, 1992 *
P450-Inducer not available Duke, 1992 *
Pediculicide 2.3 x pyrethrin Duke, 1992 *
Perfume not available Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide not available Duke, 1992 *
Rubefacient not available Martindale's 29th
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Isanthus brachiatus Plant not available not available not available Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Juniperus sabina Plant not available not available not available Duke, 1992 *
Lantana camara Shoot not available 27.0 -0.1 Duke, 1992 *
Laurus nobilis Leaf Essent. Oil 211400.0 620000.0 1.3 Duke, 1992 *
Laurus nobilis Fruit Essent. Oil 228000.0 283700.0 -0.9 Duke, 1992 *
Laurus nobilis Essential Oil not available not available not available Duke, 1992 *
Laurus nobilis Leaf 375.0 24800.0 2.7 Duke, 1992 *
Lavandula angustifolia Flower not available not available not available Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Lavandula latifolia Plant 1000.0 3434.0 0.4 Leung, A.Y., Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, John Wiley & Sons, New York, 1980.
Lavandula x hybrida Shoot 1750.0 2465.0 -0.1 Tucker, A.O., Maciarello, M.J., Angell, S., Espaillat, J.R., and French, E.C. 1993. The Essential Oil of Lavandula x hybrida Balb. ex Ging., a Distinct Hybrid from L. x heterophylla Poir. (Labiatae). J. Ess. Oil Res. 5: 443-445.
Lavandula x intermedia Plant 315.0 1110.0 -0.3 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Lepechinia calycina Plant not available 985.0 -0.3 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Levisticum officinale Root not available not available not available Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Lindera benzoin Shoot Essent. Oil 100000.0 160000.0 not available Tucker, A. O. and Debaggio, T. 2000. The Big Book of Herbs. Interweave Press, Inc. Loveland, CO. 688 pp.
Lindera benzoin Twig 315.0 320.0 not available Duke, 1992 *
Lippia alba Plant not available not available not available Grenand, P., Moretti, C., and Jacquemin, H. 1987. Pharmacopees Traditionnelles en Guyane. l'ORSTROM, Paris. 569 pp.
Litsea glaucescens Shoot 425.0 565.0 -0.1 Tucker, et al, EB46(1):21-24.1992
Lycopus virginicus Plant 7.0 18.0 -0.6 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Magnolia denudata Bark not available not available not available Duke, 1992 *
Magnolia denudata Bulb not available not available not available Duke, 1992 *