An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
  1. Home
  2. 1,8-CINEOLE

1,8-CINEOLE

Chemical ID
18CINEOLE
Ubiquitous
No
List of known dosages
Dosage Reference
LD50=2,480 (orl rat) Zebovitz, T. C. Ed. 1989. Part VII. Flavor and Fragrance Substances, in Keith L. H. and Walters, D.B., eds. Compendium of Safety Data Sheets for Research and Industrial Chemicals. VCH Publishers, New York. 3560-4253.
LD50=3,480 mg/kg
LD50=>5,000 (dml rbt)
LD100=1,000 ug/ml
LD50=100 mg/kg (ims mus) Hansel, R., Keller, K., Rimpler, H., and Schneider, G. eds. 1992. Hager's Handbuch der Pharmazeutischen Praxis, Drogen (A-D), 1209 pp., 1993 (E-O), 970 pp., 1994 (P-Z), 1196 pp. Springer-Verlag, Berlin.
Download these results as:
CSV
EXCEL
PDF
List of chemical activities.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Activity Dosage Reference
Expectorant Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
FLavor FEMA 1-200 Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Fungicide *
Gastroprotective *
Gram(+)icide *
Gram(-)icide *
Hepatotonic *
Herbicide IC50=78 uM Keeler, R.F. and Tu, A.T. eds. 1991. Toxicology of Plant and Fungal Compounds. (Handbook of Natural Toxins Vol. 6) Marcel Dekker, Inc. NY. 665 pp.
Hypotensive *
Inflammatory inj *
Insectifuge *
Irritant Rinzler, C. A. 1990. The Complete Book of Herbs, Spices and Condiments. Facts on File, New York. 199 pp.
Myorelaxant Newall, C. A., Anderson, L. A. and Phillipson, J. D. 1996. Herbal Medicine - A Guide for Health-care Professionals. The Pharmaceutical Press, London. 296pp.
Nematicide Nigg, H.N. and Seigler, D.S., eds. 1992. Phytochemical Resources for Medicine and Agriculture. Plenum Press, New York. 445 pp.
Neurotoxic *
P450-Inducer *
Pediculicide 2.3 x pyrethrin *
Perfume Aloe Research Council - Duke writeup of non-peer reviewd book by Coats and draft by Henry
Pesticide *
Rubefacient Martindale's 29th
Download these results as:
CSV
EXCEL
PDF
List of chemical plants.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Plant Name Plant Part Low Parts Per Million High Parts Per Million Standard Deviation Reference
Myristica fragrans Seed 440.0 5600.0 0.2 *
Myrtus communis Plant 135.0 2065.0 0.0 *
Myrtus communis Leaf 135.0 2250.0 -0.2 *
Nepeta racemosa Shoot 1150.0 -0.1 Baser, K.H.C., Ozek, T., Akgul, A. and Tumen, G. 1993. Composition of the Essential Oil of Nepeta racemosa Lam. J. Ess. Oil Res. 5: 215-7.
Nepeta racemosa Shoot 1150.0 -0.1 Baser, K.H.C., Ozek, T., Akgul, A. and Tumen, G. 1993. Composition of the Essential Oil of Nepeta racemosa Lam. J. Ess. Oil Res. 5: 215-7.
Nicotiana tabacum Leaf List, P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979.
Ocimum basilicum Plant 135.0 -0.5 Die Nahrung. Pino, J., Rosado, A., Goire, I., Roncal, E., and Garcia, I. 1993. Analysis of the Essential Oil from Cuban Basil. Die Nahrung 37:(5): 501-504.
Ocimum basilicum Plant 135.0 -0.5 Die Nahrung. Pino, J., Rosado, A., Goire, I., Roncal, E., and Garcia, I. 1993. Analysis of the Essential Oil from Cuban Basil. Die Nahrung 37:(5): 501-504.
Ocimum canum Shoot =ICMR(Indian Council of Medical Research).1976.Medicinal Plants of India.Vol.1.Indian Council of Med. Res.Cambridge Printing Works, New Delhi.487 pp;ICMR.1987.Medicinal Plants of India.Vol.2.Indian Council of Med. Res.Cambr. Printing Works,New Delhi.600pp
Ocimum gratissimum Plant 10.0 65.0 -0.5 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Ocimum gratissimum Shoot 690.0 -0.1 Vostrowsky, O., Garbe, W., Bestmann, H.J. and Maia, J.G.S. 1990. Essential Oil of Alfavaca, Ocimum gratissimum, from Brazilian Amazon. Zeitschr. Naturforschung 45(C): 1073-6.
Ocimum kilimandscharicum Flower 1130.0 1960.0 -0.2 Charles, D.J., and Simon, J.E. 1992. Essential Oil Constituents of Ocimum killimandscharicum Guerke. J. Ess. Oil Res., 4: 125-128.
Ocimum kilimandscharicum Shoot 715.0 6200.0 0.0 Charles, D.J., and Simon, J.E. 1992. Essential Oil Constituents of Ocimum killimandscharicum Guerke. J. Ess. Oil Res., 4: 125-128.
Ocimum tenuiflorum Leaf 35.0 1710.0 -0.3 *
Origanum minutiflorum Shoot 60.0 140.0 -0.1 Baser, K.H.C., Tumen, G., Sezik, E. 1991. The Essential Oil of Origanum minutiflorum O. Schwarz and P.H. Davis. J. Ess. Oil Res. 3: 445-446.
Origanum onites Plant 23.0 -0.6 Lawrence, B.M., Essential Oils 1976-1977, Essential Oils 1978, Essential Oils 1979-1980.
Origanum onites Shoot 0.0 -0.1 Biondi, D., Cianci, P., Geraci, C. and Ruberto, G. 1993. Antimicrobial Activity and Chemical Composition of Essential Oils from Sicilian Aromatic Plants. Flav. & Frag. J. 8: 331-7.
Origanum sipyleum Shoot 265.0 -0.1 Baser, K.H.C., Ozek, T., Kurkcuoglu, M. and Tumen, G. 1992. Composition of the Essential Oil of Origanum sipyleum of Turkish Origin. J. Ess. Oil Res. 4: 139-142.
Origanum sipyleum Shoot 20.0 -0.1 Baser, K.H.C., Ozek, T., Kurkcuoglu, M. and Tumen, G. 1992. Composition of the Essential Oil of Origanum sipyleum of Turkish Origin. J. Ess. Oil Res. 4: 139-142.
Origanum sipyleum Shoot 265.0 -0.1 Baser, K.H.C., Ozek, T., Kurkcuoglu, M. and Tumen, G. 1992. Composition of the Essential Oil of Origanum sipyleum of Turkish Origin. J. Ess. Oil Res. 4: 139-142.