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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Cytotoxic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PULCHELLIN ED50=1-2 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
PULVEROCHROMENOL *
PUNICIC-ACID *
QUADRIGEMINE EC100=8uM *
QUADRIGENIN *
QUASSIMARIN 1-4,000 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
QUERCETAGETIN-6,7,3',4'-TETRAMETHYLETHER *
QUERCETIN ED50=70 ug/ml Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
QUERCETIN IC82=100 ug/ml Planta Medica, 57: A113, 1991.
QUINICINE IC50=3.2 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUINIDINONE IC50=17.7 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE IC50=183 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
RADIATIN 0.39 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
RETUSIN ED50=>25 ug/ml Arisawa, M., Hayashi, T., Shimizu, M., Morita, N., Bai, H., Kuze, S., and Ito, Y. Isolation And Cytotoxicity Of Two New Flavonoids From Chrysosplenium grayanum And Related Flavonols. J. Natural Products, 54(3): 898-901, 1991.
RHEIN CD50=3.4 ug/ml *
RHOEADINE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ROBUSTAFLAVONE-4'-METHYL-ETHER Lin, L., Kuo, Y., Chou, C. 2000. Cytotoxic Biflavonoids from Selaginella delicatula. J. Natural Products, 63(5): 627-630.
ROLLINIASTATIN-1 9PS ED50=0.000045 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ROLLINIASTATIN-2 9PS ED50=0.00023 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ROLLINICIN 9PS ED50=0.000000029 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Avena sativa Oats 4 630
Averrhoa carambola Carambola; Star Fruit 1 0
Avicennia alba 2 760
Avicennia marina 1 12, 000
Avicennia officinalis 2 4, 720
Avicennia tomentosa 2 200
Azadirachta indica Neem 6 4, 010
Balanops australiana 1 360
Ballota nigra Black Horehound 5 2, 003
Banisteriopsis caapi Ayahuasca; Caapi; Yage; Soul Vine; Spirit Vine 2 0
Baptisia sp 1 0
Baptisia tinctoria Wild Indigo 3 0
Barosma betulina Buchu 1 0
Basella alba Vinespinach 2 0
Bauhinia vahlii 1 0
Berberis vulgaris Barberry 8 269, 200
Bertholletia excelsa Brazilnut; Brazilnut-Tree; Creamnut; Paranut 1 0
Beta vulgaris Beet; Beetroot; Sugar Beet; Garden Beet 4 0
Betula alba 1 0
Betula alleghaniensis 1 0