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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Cytotoxic

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
PULCHELLIN ED50=1-2 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
PULVEROCHROMENOL *
PUNICIC-ACID *
QUADRIGEMINE EC100=8uM *
QUADRIGENIN *
QUASSIMARIN 1-4,000 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
QUERCETAGETIN-6,7,3',4'-TETRAMETHYLETHER *
QUERCETIN ED50=70 ug/ml Matsukawa, Y., et al. The Effect of Quercetin and Other Flavonoids on Cell Cycle Progresssion and Growth of Human Gastric Cancer Cells. Planta Medica, 56(6): 677, 1990.
QUERCETIN IC82=100 ug/ml Planta Medica, 57: A113, 1991.
QUINICINE IC50=3.2 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUINIDINONE IC50=17.7 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
QUININE IC50=183 ug/ml Vlietinck, A.J. and Dommisse, R.A. eds. 1985. Advances in Medicinal Plant Research. Wiss. Verlag. Stuttgart.
RADIATIN 0.39 ppm Biosyn. Prod. Cancer Chemotherapy (Petit et al)
RETUSIN ED50=>25 ug/ml Arisawa, M., Hayashi, T., Shimizu, M., Morita, N., Bai, H., Kuze, S., and Ito, Y. Isolation And Cytotoxicity Of Two New Flavonoids From Chrysosplenium grayanum And Related Flavonols. J. Natural Products, 54(3): 898-901, 1991.
RHEIN CD50=3.4 ug/ml *
RHOEADINE Jeffery B. Harborne and H. Baxter, eds. 1983. Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor & Frost, London. 791 pp.
ROBUSTAFLAVONE-4'-METHYL-ETHER Lin, L., Kuo, Y., Chou, C. 2000. Cytotoxic Biflavonoids from Selaginella delicatula. J. Natural Products, 63(5): 627-630.
ROLLINIASTATIN-1 9PS ED50=0.000045 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ROLLINIASTATIN-2 9PS ED50=0.00023 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
ROLLINICIN 9PS ED50=0.000000029 ppm Rupprect, J. K., Hui, Y. H., and McLaughlin, J. L., Annonaceous acetogenins: a review, J. Nat. Prod, 53(2), 1990, 237-238.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Maackia amurensis 1 0
Machaerocereus gummosus 1 8, 000
Macleaya cordata Plume Poppy 1 0
Maclura pomifera Osage-Orange; Hedge Apple 5 31, 344
Macroptylium atropurpureum 1 0
Macroptylium bracteatum 1 10
Macroptylium lathyroides 1 0
Macroptylium martii 1 0
Macrotyloma axillare 1 0
Macrotyloma uniflora 1 0
Madhuca microphylla 1 1, 860
Madhuca nerifolia 1 1, 120
Magnolia denudata Hsin-I; Xin-Yi 2 0
Magnolia fargesii Hsin-I; Xin-Yi 2 0
Magnolia kobus Hsin-I; Xin-Yi 5 0
Magnolia officinalis Chinese Magnolia; Hou Pu; Magnolia-Bark 5 0
Mahonia aquifolium Oregon Grape; Blue Barberry; Holly Barberry; Holly Mahonia; Mountain Grape 4 360
Mahonia fargesii 1 0
Mahonia fortunei 1 0
Mahonia gracilipes 1 0