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Biological Activity COX-1-Inhibitor

List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
(+)-CATECHIN IC50=183-279 uM (cf indomethacin IC50=1 uM) Duke, 1992 *
(-)-EPIAFZELECHIN IC50=15 uM/ Min, K. R. et al. 1999. (-)-epiafzelechin: Cyclooxygenase-1 Inhibitor and Anti-Inflammatory Agent from Aerial Parts of Celastrus orbiculatus. Planta Med., 65(5): 460-462.
3,4-METHYLENE-DIOXYCINNAMIC-ACID-BORNYL-ESTER IC16=100 ug/ml Duke, 1992 *
AIPHANOL not available Duke, 1992 *
ANTHOCYANINS IC45=125 ug/ml Duke, 1992 *
APIGENIN IC65=1,000 uM Duke, 1992 *
BAICALEIN 100 ug/ml Fukutake, M., Yokota, S., Kawamura, H., Iizuka, A., Amagaya, S., Fukuda, K., Komatsu, Y. 1998. Inhibitory effect of Coptidis rhizoma adn Scutellariae radix on azoxymethane-induced aberrant crypt foci formation in rat colon. Biol Pharm Bull, 21(8): 814-817
BETA-CAROTENE IC78=50 ug/ml Duke, 1992 *
CATECHIN IC50=80 uM (cf indomethacin IC50=1 uM) Duke, 1992 *
CINNAMIC-ACID-BORNYL-ESTER IC66=100 ug/ml Duke, 1992 *
CIRSILINEOL IC37=1,000 uM Duke, 1992 *
CIRSIMARITIN IC50=1,000 uM Duke, 1992 *
CYANIDIN-3-O-GLUCOSIDE IC30=100 ug/ml Duke, 1992 *
DIRCA-PHENOLIC-GLUCOSIDE-5 125 ug/ml Ramsewak, R. S., Nair, M. G., De Witt, D. L., Mattson, W. G., Zasada, J. 1999. Phenolic Glycosides from Dirca palustris. J. Nat. Prod., 62(11): 1558-1561.
EUGENOL IC97=1,000 uM Duke, 1992 *
FLAVOKAWAIN-B IC77=100 ug/ml Duke, 1992 *
FLAVOKAWAIN-B IC55=12.5 ug/ml Duke, 1992 *
ISOTHYMONIN IC37=1,000 uM Duke, 1992 *
LAURIC-ACID IC40=100 Duke, 1992 *
MYRICETIN-3-O-BETA-D-GLUCURONIDE IC50=0.5 uM/ Hiermann, A., Schramm, H. W., Laufer, S. 1998. Anti-Inflammatory Activity of Myricetin-3--O-beta-d-glucuronide and Related Compounds. Inflamm. Res., 47(11): 421-427.
List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Echinacea purpurea Echinacea; Eastern Purple-Coneflower; Purple-Coneflower 1 6.6000001430511475
Echinacea spp Coneflower; Echinacea 2 4.400000095367432
Elaeagnus angustifolia Russian Olive; Silver Berry 1 0
Elaeagnus commutata Silver Berry 1 1.399999976158142
Elaeagnus umbellatus Russian Olive 1 30
Elaeis guineensis African Oil Palm 1 575
Eleocharis dulcis Water chestnut 1 0
Elettaria cardamomum Cardamom 1 0
Eleutherococcus senticosus Eleuthero Ginseng; Siberian Ginseng; Spiny Ginseng; Wu jia; Ci wu jia (Pinyin) 1 150
Elsholtzia blanda Bantaluki; Bantulsi 1 1.7999999523162842
Ephedra sinica Ma Huang; Chinese Ephedra 3 82
Equisetum arvense Field Horsetail; Horsetail 2 98
Eriobotrya japonica Loquat 1 68
Eriodictyon californicum Yerba Santa; California Yerba Santa; Hierba Santa; Mountain Balm; Bear's Weed; Consumptive's Weed; Tarweed; Gum Bush; Holy Herb 2 1, 818
Eryngium foetidum Culantro; Cilantro; False Coriander; Shadow-Beni; Stinkweed; Stinkdistel (Ger.) 1 300
Erythrina berteroana Pito 1 14
Erythrina fusca Coral Bean; Gallito 1 250
Erythroxylum coca Coca 1 7
Eucalyptus brassiana Brasses' Eucalyptus 1 0
Eucalyptus citriodora Lemon Eucalyptus; Lemon-Scented Gum; Spotted Gum; Citron-Scented Gum 1 0