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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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Antimalarial

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
NARDISINONE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NARDOPEROXIDE IC50=1.4 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NB-METHYLAFFINISINE IC50=5->5 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-A IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-B IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NEUROLENIN-C/D IC50=0.6 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBANDIOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMBIN IC50=50 ug/ml *
NIMBININ IC50=0.77 ug/ml *
NIMBOLIDE IC50=1.74 ug/mL *
NIMBOLIDE IC50=0.001 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NIMOCINOL IC50=50 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NOR-TILIACORINE-A IC50=0.56 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORFLUOROCURARINE IC50=129 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
NORTILIACORININE-A *
NYASOL IC50=12 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLEXOSTEMIN IC50=1.6-3.6 ug/ml Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
O-METHYLMACRALSTONINE IC50=0.9 uM Rukunga, G. and Simons, A. J. 2006. The Potential of Plants as a Source of Antimalarial Agents - A Review. Africa Herbal Antimalaria Meeting. PlantaPhile Publications, Berlin. 72 pp.
OBAMEGINE IC50=0.51 ug/ml (1/4 x chloroquine) *
OLEANOLIC-ACID IC50=70-89 ug/ml *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Tovomita pyrifolia 1 0
Triadenum japonicum 1 0
Tribulus terrestris Puncture-vine 3 0
Tridax procumbens Coatbuttons; Mexican daisy 1 0
Trifolium pratense Red Clover; Purple Clover; Peavine Clover; Cowgrass 2 168
Trigonella foenum-graecum Fenugreek; Greek Clover; Greek Hay; Bockshornklee (Ger.); Alholva (Sp.) 2 0
Trilisa odoratissima Carolina Vanilla; Deer's Tongue; Hound's Tongue; Vanilla Plant 1 0
Tripterygium wilfordiim Yellow Vine 1 0
Triticum aestivum Wheat 1 0
Tussilago farfara Coltsfoot 2 3, 600
Ulex europaeus Gorse 1 0
Umbellularia californica California Bay 1 40
Uncaria catechu Gambir; Pale Catechu 2 0
Uncaria guianensis Cat's Claw; Una de Gato; Garabato Colorado; Tambor Huasca; Ungunagi 2 0
Uncaria tomentosa Cat's Claw; Garabato Amarillo; Una de Gato 5 33, 480
Urginea maritima European Squill 1 0
Urtica dioica European Nettle; Stinging Nettle 4 26, 070
Uvaria sp. 2 0
Vaccinium corymbosum Blueberry 5 0
Vaccinium macrocarpon Cranberry; Large Cranberry; American Cranberry 3 750