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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture

Biological Activity 5-Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
ZINGERONE *
TROLOX IC50 (uM)=170 *
TRANS-TRANS-5-ETHYL-4,6,7-TRITHIA-2,8-DECADIENE-4-S-OXIDE *
TRANS-N-PROPYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER *
TRANS-METHYLSULPHINOTHIOIC-ACID-S-1-PROPENYLESTER *
TRANS-5-ETHYL-4,6,7-TRITHIA-2-DECENE-4-S-OXIDE *
SHOGAOL *
SANGUINARINE Mills, Simon and Bone, Kerry. 2000. Phytotherapy. Churchill
Livinston, Edinburgh.
RESVERATROL IC50=1-9 uM *
RESVERATROL IC50=48 uM *
QUERCETIN IC50 (uM)=4 *
PROPYL-GALLATE IC50 (uM)=5 *
PARTHENOLIDE *
OSTHOL *
NORDIHYDROGUAIARETIC-ACID *
NDGA IC50 (uM)=0.8 *
N-PROPYLSULPHINOTHIOIC-ACID-S-N-PROPYLESTER *
MYRCETIN IC50 (uM)=13 *
KAEMPFEROL IC50 (uM)=20 *
GAMMA-BOSWELLIC-ACID *
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List of Activity Plants.
Click on column headings to sort table by that column.
Plant Name Common Name Chemical Count Total Parts Per Million
Zingiber officinale Ginger 6 0
Zea mays Corn 1 0
Zanthoxylum clava-herculis Pepperbark; Southern Prickly Ash; Hercules'-Club; West Indian Yellowwood 1 0
Zanthoxylum americanum Northern Prickly Ash 1 0
Withania somnifera Ashwagandha 1 0
Vitis vinifera Grape; European Grape; Wine Grape; Grapevine; Vigne Vinifere (Fr.); Weinrebe (Ger.); Parra (Sp.); Vid (Sp.) 4 1, 446, 809.6000022888
Vitex agnus-castus Chaste-Tree 1 0
Viola tricolor Pansy; Wild Violet 1 0
Viola odorata Common Violet; Sweet Violet 2 0
Vigna radiata Green Gram; Mungbean 2 0
Vicia faba Broadbean; Faba Bean; Habas 1 0
Viburnum prunifolium Black Haw 2 0
Viburnum opulus Crampbark; European Cranberry Bush; Guelder Rose; Snowballbush 4 0
Vanilla planifolia Vanilla; Bourbon Vanilla 1 92
Valeriana officinalis Valerian; Common Valerian; Garden-Heliotrope 2 0
Vaccinium vitis-idaea Cowberry; Lingen; Lingonberry 3 0
Vaccinium myrtillus Bilberry; Whortleberry; Dwarf Bilberry 2 0
Vaccinium macrocarpon Cranberry; Large Cranberry; American Cranberry 2 750
Vaccinium corymbosum Blueberry 3 0
Urtica dioica European Nettle; Stinging Nettle 3 0