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Dr. Duke's Phytochemical and Ethnobotanical Databases
U.S. Department of Agriculture
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  2. 5-Lipoxygenase-Inhibitor

5-Lipoxygenase-Inhibitor

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List of activity chemicals.
Click on column headings to sort table by that column. *Unless otherwise noted all references are to (Duke, 1992)
Chemical Name Dosage Reference
3-HYDROXY-FLAVONE IC50 (uM)=16 *
BAICALEIN IC50=0.1-5 uM *
CAPSAICIN *
CARNOSOL IC50 (uM)=2 *
CURCUMIN *
FISETIN IC50 (uM)=11 *
KAEMPFEROL IC50 (uM)=20 *
MYRCETIN IC50 (uM)=13 *
NDGA IC50 (uM)=0.8 *
NORDIHYDROGUAIARETIC-ACID *
PROPYL-GALLATE IC50 (uM)=5 *
QUERCETIN IC50 (uM)=4 *
SHOGAOL *
TROLOX IC50 (uM)=170 *
ZINGERONE *
AESCULETIN IC50=0.1-5 uM *
ACETYL-BETA-BOSWELLIC-ACID 7 uM Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
ACETYL-11-KETO-BETA-BOSWELLIC-ACID 2 uM Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
ALPHA-BOSWELLIC-ACID *
BETA-BOSWELLIC-ACID 5 uM Sabinsa: A series of well documented proprietary PR booklets,
e.g.Sabinsa Corps. 1998. Bronchial Asthma - Its etiology and control with traditional herbal extracts. Sabinsa Corporation. Piscataway, NJ. 49 pp.
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List of Activity Plants.
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Plant Name Common Name Chemical Count Total Parts Per Million
Hordeum vulgare Barley; Barleygrass 2 0
Abelmoschus moschatus Ambrette; Musk Okra; Tropical Jewel Hibiscus; Muskmallow 2 0
Brassica oleracea var. italica Broccoli; Heading Broccoli; Sprouting Broccoli; Cape Broccoli; Purple Cauliflower; Asparagus Broccoli; Winter Broccoli; Calabrese 2 0
Tsuga canadensis Eastern Hemlock 1 0
Pinus mugo Dwarf Pine; Swiss Mountain Pine 2 0
Eupatorium perfoliatum Boneset 2 0
Macleaya cordata Plume Poppy 1 0
Araucaria bidwillii Monkey puzzle 1 0
Citrus reticulata Mandarin; Tangerine 1 0
Hamamelis virginiana Witch Hazel 2 0
Borago officinalis Borage; Beebread; Beeplant; Talewort 2 0
Thymus vulgaris Common Thyme; Garden Thyme; Thyme 1 0
Equisetum arvense Field Horsetail; Horsetail 2 0
Ligustrum lucidum Chinese Privet; Glossy Privet; Ligustri Fructus; Privet; White Waxtree 1 0
Anastatica hierochuntica Jericho Rose 1 0
Cinchona spp Quinine 1 0
Zingiber officinale Ginger 6 0
Prunus spinosa Blackthorn; Sloe 2 0
Barosma betulina Buchu 1 0
Teucrium botrys Field Germander 1 0